APC 366

Tocris Bioscience, part of Bio-Techne | Catalog # 2511

Tryptase inhibitor
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Key Product Details

Description

Tryptase inhibitor

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Product Description

APC 366 is a selective inhibitor of mast cell tryptase (Ki = 7.1 μM) that inhibits tryptase-induced histamine release from human tonsil and lung cells. Reduces airway inflammation and blocks postchallenge airway hyperresponsiveness in vivo.

Product Specifications

Molecular Weight

440.50

Formula

C22H28N6O4

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

N-(1-Hydroxy-2-naphthoyl)-L-arginyl-L-prolinamide

CAS Number

158921-85-8

PubChem ID

177340

InChI Key

SKYWIMYOGAWOMB-IRXDYDNUSA-N

SMILES

OC2=C(C(N[C@@H](CCCNC(N)=N)C(N3[C@H]([C@](N)=O)CCC3)=O)=O)C=CC1=CC=CC=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 5mg/ml in 20% ethanol / water

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Background References

References are publications that support the biological activity of the product.

Product Documents for APC 366

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for APC 366

For research use only

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