Alprostadil

Tocris Bioscience, part of Bio-Techne | Catalog # 1620

Prostaglandin. Vasodilator and antiplatelet agent in vivo
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Key Product Details

Description

Prostaglandin. Vasodilator and antiplatelet agent in vivo

Alternative Names

PGE1,Prostaglandin E1

View all Additional Prostanoid Receptor Compounds »

Product Description

Alprostadil is a prostaglandin with some selectivity for EP3 and EP4 receptors (Ki values are 1.1, 2.1, 36, 10 and 33 nM for mouse EP3, EP4, EP1, EP2 and IP receptors respectively). Inhibits platelet aggregation and is a vasodilator in vivo.

Product Specifications

Molecular Weight

354.49

Formula

C20H34O5

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

(11α,13E,15S)-11,15-Dihydroxy-9-oxo-prost-13-en-1-oic acid

CAS Number

745-65-3

PubChem ID

5280723

InChI Key

GMVPRGQOIOIIMI-DWKJAMRDSA-N

SMILES

CCCCC[C@H](O)/C=C/[C@@H]1[C@H](C(C[C@H]1O)=O)CCCCCCC(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
Ethanol 17.72 50

Preparing Stock Solutions for Alprostadil

The following data is based on the product molecular weight 354.49

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 5.64 mL 28.21 mL 56.42 mL
2.5 mM 1.13 mL 5.64 mL 11.28 mL
5 mM 0.56 mL 2.82 mL 5.64 mL
25 mM 0.11 mL 0.56 mL 1.13 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for Alprostadil

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Alprostadil

For research use only

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