Adenine
Tocris Bioscience, part of Bio-Techne | Catalog # 4202
Adenine receptor agonist
Product Description
Adenine is a high affinity adenine receptor agonist (Ki = 18 nM at rat adenine receptor). Inhibits forskolin-stimulated cAMP formation in CHO cells transfected with the adenine receptor; also stimulates GTPγS binding (pEC50 values are 8.54 and 7.21 respectively).Product Specifications
Molecular Weight
171.59
Formula
C5H5N5.HCl
Storage
Desiccate at RT
Purity
≥99% (HPLC)
Chemical Name
6-Aminopurine hydrochloride
CAS Number
2922-28-3
PubChem ID
76219
InChI Key
UQVDQSWZQXDUJB-UHFFFAOYSA-N
SMILES
NC1=C2C(NC=N2)=NC=N1.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 17.16 | 100 | |
| DMSO | 17.16 | 100 |
Preparing Stock Solutions
for Adenine
The following data is based on the product molecular weight 171.59
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 5.83 mL | 29.14 mL | 58.28 mL |
| 5 mM | 1.17 mL | 5.83 mL | 11.66 mL |
| 10 mM | 0.58 mL | 2.91 mL | 5.83 mL |
| 50 mM | 0.12 mL | 0.58 mL | 1.17 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Bender Characterization of an orphan G protein-coupled receptor localized in the dorsal root ganglia reveals adenine as a signaling molecule. Proc.Natl.Acad.Sci.
- Gorzalka Evidence for the functional expression and pharmacological characterization of adenine receptors in native cells and tissues. Mol.Pharmacol. 2005 PMID: 15604413
Product Specific Notices for Adenine
For research use only
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