Ac₄GalN6yne

Product Description

Ac₄GalN6yne is a cell-permeable alkyne-containing monosaccharide building block. It can be used in Bio-Orthogonal Cell-specific Tagging of Glycoproteins (BOCTAG) technique. In this strategy, cells carrying an artificial biosynthetic pathway (B. longum NahK and mut-AGX1) can generate alkyne-tagged UDP-GalN6yne, that are then used by glycosyltransferases to chemically tag the glycoproteome. Ac₄GalN6yne can be used for bioorthogonal labelling in vitro and mouse models.

Solubility

Preparing Stock Solutions for Ac₄GalN6yne

The following data is based on the product molecular weight 441.43

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.2 mM	11.33 mL	56.63 mL	113.27 mL
1 mM	2.27 mL	11.33 mL	22.65 mL
2 mM	1.13 mL	5.66 mL	11.33 mL
10 mM	0.23 mL	1.13 mL	2.27 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Cioce Cell-specific bioorthogonal tagging of glycoproteins. Nat.Commun. 2022 PMID: 36284108