ABP 688

Name: ABP 688
Brand: Tocris Bioscience
SKU: 5229

Tocris Bioscience, part of Bio-Techne | Catalog # 5229

Citations (6)

COA / SDS

High affinity human mGlu5 antagonist

Discontinued Product

5229 has been discontinued. View all Group I mGluR Antagonists products.

Key Product Details

Description:	High affinity human mGlu₅ antagonist
Chemical Name:	3-[2-(6-Methyl-2-pyridinyl)ethynyl]-2-cyclohexene-1-one O-methyloxime
Purity:	≥98% (HPLC)
Molecular Weight:	240.3

View Full Technical Details for ABP 688

Technical Data
Citations

Biological Activity for ABP 688

ABP 688 is a high affinity human mGlu₅ receptor antagonist (K_i = 1.7 nM). Inhibits glutamate-induced calcium release from L(tk-) cells expressing human mGlu₅ receptors (IC₅₀ = 2.3 nM).

Technical Data for ABP 688

M. Wt	240.3
Formula	C₁₅H₁₆N₂O
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	924298-51-1
PubChem ID	11481862
InChi Key	CNNZLFXCUQLKOB-BMRADRMJSA-N
Smiles	CC1=CC=CC(C#CC(CCC2)=C/C2=N/OC)=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for ABP 688

References are publications that support the biological activity of the product.

Hintermann ABP688, a novel selective and high affinity ligand for the labeling of mGlu₅ receptors: identification, in vitro pharmacology, pharmacokinetic and biodistribution studies. Bioorg.Med.Chem. 2007 PMID: 17110115

ABP 688

Tocris Bioscience, part of Bio-Techne | Catalog # 5229

Key Product Details

Biological Activity for ABP 688

Technical Data for ABP 688

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for ABP 688

Product Documents for ABP 688

COA

Certificate of Analysis

SDS

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