α,β-Methyleneadenosine 5'-triphosphate trisodium salt

Name: α , β -Methyleneadenosine 5'-triphosphate trisodium salt
Brand: Tocris Bioscience
SKU: 3209
Rating: 4 (1 reviews)

Tocris Bioscience a Bio-Techne Brand

Catalog # 3209

Citations (2)

(1)

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Key Product Details

Description:	Non-selective P2 agonist
Alternative Names:	α,β-meATP
Chemical Name:	α,β-Methyleneadenosine 5'-triphosphate trisodium salt
Purity:	≥98% (HPLC)
Molecular Weight:	571.15

View Full Technical Details for α,β-Methyleneadenosine 5'-triphosphate trisodium salt

Biological Activity

α,β-Methyleneadenosine 5'-triphosphate trisodium salt is a P2-purinoceptor agonist. Also shown to inhibit adenylate cyclase (K_i = 0.5 mM).

Technical Data

M. Wt	571.15
Formula	C₁₁H₁₅N₅Na₃O₁₂P₃
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	1343364-54-4
PubChem ID	90488813
InChi Key	CBAGKCWFSRTVER-MTQUBGKESA-K
Smiles	O[C@@H]1[C@@H](COP(CP([O-])(OP([O-])(O)=O)=O)([O-])=O)O[C@@H](N3C2=NC=NC(N)=C2N=C3)[C@@H]1O.[Na+].[Na+].[Na+]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	57.12	100

Preparing Stock Solutions

The following data is based on the product molecular weight 571.15.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.75 mL	8.75 mL	17.51 mL
5 mM	0.35 mL	1.75 mL	3.50 mL
10 mM	0.18 mL	0.88 mL	1.75 mL
50 mM	0.04 mL	0.18 mL	0.35 mL

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Reconstitution Calculator

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References

References are publications that support the biological activity of the product.

Burnstock and Kennedy Is there a basis for distinguishing two types of P2-purinoceptor? Gen.Pharmacol 1985 PMID: 2996968
Krug α,β-Methylene-adenosine 5'-triphosphate. J.Biol.Chem. 1973 PMID: 4686923

Citations for α,β-Methyleneadenosine 5'-triphosphate trisodium salt (2)

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Citations are publications that use Bio-Techne products. Selected citations for α,β-Methyleneadenosine 5'-triphosphate trisodium salt include:

Palygin et al. (2018) Characterization of purinergic receptor expression in ARPKD cystic epithelia. Purinergic Signal. 14:485
PMID: 30417216
Haanes and Edvinsson (2014) Expression and characterization of purinergic receptors in rat middle meningeal artery-potential role in migraine. PLoS One. 9:e108782
PMID: 25265286

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P2 agonist

Name: Anonymous

Species: Human

P2X1 and P2X3 agonist, the product works as expected.

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Product Documents

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.