A 784168

Tocris Bioscience, part of Bio-Techne | Catalog # 4319

Potent and selective TRPV1 antagonist
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Key Product Details

Description

Potent and selective TRPV1 antagonist

View all TRPV Antagonists »

Product Description

A 784168 is a potent TRPV1 antagonist (IC50 = 25 nM for inhibition of TRPV1 activation by 50 nM capsaicin). Displays no activity against a range of receptors, including TRPA1, GABA, opioid, and purinergic receptors.

Product Specifications

Molecular Weight

479.40

Formula

C19H15F6N3O3S

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

3,6-Dihydro-3'-(trifluoromethyl)-N-[4-[(trifluoromethyl)sulfonyl]phenyl]-[1(2H),2'-bipyridine]-4-carboxamide

CAS Number

824982-41-4

PubChem ID

11420211

InChI Key

SDUAWRFBHRAFBM-UHFFFAOYSA-N

SMILES

O=C(NC3=CC=C(S(=O)(C(F)(F)F)=O)C=C3)C(CC2)=CCN2C1=C(C(F)(F)F)C=CC=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 47.94 100
Ethanol 23.97 50

Preparing Stock Solutions for A 784168

The following data is based on the product molecular weight 479.40

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.09 mL 10.43 mL 20.86 mL
5 mM 0.42 mL 2.09 mL 4.17 mL
10 mM 0.21 mL 1.04 mL 2.09 mL
50 mM 0.04 mL 0.21 mL 0.42 mL

Calculators

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Product Documents for A 784168

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for A 784168

For research use only

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