A 412997 dihydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 4552

Selective D4 agonist
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Key Product Details

Description

Selective D4 agonist

View all Dopamine D4 Receptor Agonists »

Product Description

A 412997 dihydrochloride is a selective agonist for the dopamine D4 receptor (Ki values are 7.9 and 12.1 nM for human D4 and rat D4 receptors). Displays no affinity (<1000 nM) for other dopamine receptors. Shows efficacy in rat models of ADHD and short-term memory.

Product Specifications

Molecular Weight

382.33

Formula

C19H23N3O.2HCl

Storage

Desiccate at RT

Purity

≥98% (HPLC)

Chemical Name

N-(3-Methylphenyl)-4-(2-pyridinyl)-1-piperidineacetamide

CAS Number

1347744-96-0

PubChem ID

90488953

InChI Key

KIGNSSHMCNBHQX-UHFFFAOYSA-N

SMILES

O=C(CN2CCC(C3=CC=CC=N3)CC2)NC1=CC=CC(C)=C1.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 38.23 100
DMSO 19.12 50

Preparing Stock Solutions for A 412997 dihydrochloride

The following data is based on the product molecular weight 382.33

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.62 mL 13.08 mL 26.16 mL
5 mM 0.52 mL 2.62 mL 5.23 mL
10 mM 0.26 mL 1.31 mL 2.62 mL
50 mM 0.05 mL 0.26 mL 0.52 mL

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Background References

References are publications that support the biological activity of the product.

Product Documents for A 412997 dihydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for A 412997 dihydrochloride

For research use only

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