7-NINA

Name: 7-NINA
Brand: Tocris Bioscience
SKU: 0800

Tocris Bioscience, part of Bio-Techne | Catalog # 0800

Citations (26)

COA / SDS

Non-selective NOS inhibitor. Sodium salt of 7-nitroindazole (Cat. No. 0602)

Discontinued Product

0800 has been discontinued. View all Additional NOS Inhibitors products.

Key Product Details

Description:	Non-selective NOS inhibitor. Sodium salt of 7-nitroindazole (Cat. No. 0602)
Chemical Name:	7-Nitroindazole monosodium salt
Purity:	≥98%
Molecular Weight:	185.12

View Full Technical Details for 7-NINA

Technical Data
Citations

Biological Activity for 7-NINA

7-NINA is a sodium salt of the non-selective NOS inhibitor 7-nitroindazole (Cat. No. 0602).

Technical Data for 7-NINA

M. Wt	185.12
Formula	C₇H₄N₃O₂Na
Storage	Desiccate at -20°C
Purity	≥98%
CAS Number	161467-34-1
PubChem ID	16760594
InChi Key	DJMLKKIIBMJGIQ-UHFFFAOYSA-N
Smiles	[Na+].[O-][N+](=O)C1=C2[N-]N=CC2=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for 7-NINA

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	9.26	50

Preparing Stock Solutions for 7-NINA

The following data is based on the product molecular weight 185.12.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	10.80 mL	54.02 mL	108.04 mL
2.5 mM	2.16 mL	10.80 mL	21.61 mL
5 mM	1.08 mL	5.40 mL	10.80 mL
25 mM	0.22 mL	1.08 mL	2.16 mL

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Reconstitution Calculator

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References for 7-NINA

References are publications that support the biological activity of the product.

Silva Increased striatal DA efflux in vivo following inhibition of cerebral nitric oxide synthase by the novel monosodium salt of 7-nitroindazole. Br.J.Pharmacol. 1995 PMID: 7533610
O'Neill Neuroprotective effects of 7-nitroindazole in the gerbil model of global cerebral ischaemia. Eur.J.Pharmacol. 1996 PMID: 8884206