7-Hydroxy-DPAT hydrobromide

Name: 7-Hydroxy-DPAT hydrobromide
Brand: Tocris Bioscience
SKU: 0706

Tocris Bioscience a Bio-Techne Brand

Catalog # 0706

COA / SDS

Discontinued Product

0706 has been discontinued. View all Dopamine D3 Receptor Agonists products.

Key Product Details

Description:	Dopamine agonist (D₃ ≥ D₂ D₄)
Chemical Name:	(±)-7-Hydroxy-2-dipropylaminotetralin hydrobromide
Purity:	≥99% (HPLC)
Molecular Weight:	328.28

View Full Technical Details for 7-Hydroxy-DPAT hydrobromide

Biological Activity for 7-Hydroxy-DPAT hydrobromide

7-Hydroxy-DPAT hydrobromide is a D₃ dopamine receptor agonist (K_i values are ~ 1, 10, 650 and ~ 5000 nM for D₃, D₂, D₄ and D₁ receptors respectively).

8-Hydroxy Isomer also available.

Technical Data for 7-Hydroxy-DPAT hydrobromide

M. Wt	328.28
Formula	C₁₆H₂₅NO.HBr
Storage	Desiccate at +4°C
Purity	≥99% (HPLC)
CAS Number	76135-30-3
PubChem ID	11957566
InChi Key	ODNDMTWHRYECKX-UHFFFAOYSA-N
Smiles	Br.CCCN(CCC)C1CCC2=CC=C(O)C=C2C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for 7-Hydroxy-DPAT hydrobromide

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	32.83	100

Preparing Stock Solutions for 7-Hydroxy-DPAT hydrobromide

The following data is based on the product molecular weight 328.28.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.05 mL	15.23 mL	30.46 mL
5 mM	0.61 mL	3.05 mL	6.09 mL
10 mM	0.30 mL	1.52 mL	3.05 mL
50 mM	0.06 mL	0.30 mL	0.61 mL

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Reconstitution Calculator

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References for 7-Hydroxy-DPAT hydrobromide

References are publications that support the biological activity of the product.

Levesque Aminotetralin drugs and D₃ receptor fuctions. Biochem.Pharmacol. 1996 PMID: 8759022
Seeman and Van Tol DA receptor pharmacology. TiPS 1994 PMID: 7940991
Daly and Waddington Behavioural effects of the D₃ DA receptor agonist 7-OH-DPAT in relation to other D₂-like agonists. Neuropharmacology 1993 PMID: 8321432
Levesque Identification, characterization, and localization of the DA D₃ receptor in rat brain using [³H]-7-hydroxy-N,N-di-n-propyl-2-aminotetralin. Proc.Natl.Acad.Sci.U.S.A. 1992 PMID: 1518841

Citations for 7-Hydroxy-DPAT hydrobromide

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7-Hydroxy-DPAT hydrobromide

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Biological Activity for 7-Hydroxy-DPAT hydrobromide

Technical Data for 7-Hydroxy-DPAT hydrobromide

Solubility for 7-Hydroxy-DPAT hydrobromide

Preparing Stock Solutions for 7-Hydroxy-DPAT hydrobromide

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for 7-Hydroxy-DPAT hydrobromide

Citations for 7-Hydroxy-DPAT hydrobromide

Product Documents for 7-Hydroxy-DPAT hydrobromide

COA

Certificate of Analysis

SDS

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