3-Aminobenzamide

Name: 3-Aminobenzamide
Brand: Tocris Bioscience
SKU: 0788

Catalog # 0788

Citations (1)

COA / SDS

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Key Product Details

Description:	PARP inhibitor
Alternative Names:	3-ABA
Molecular Weight:	136.15

View Full Technical Details for 3-Aminobenzamide

Biological Activity

3-Aminobenzamide is an inhibitor of poly(ADP-ribose) polymerase, which protects cells from UV-B-induced apoptosis via influence on the cytoskeleton.

Technical Data

M. Wt	136.15
Formula	C₇H₈N₂O
Storage	Store at RT
CAS Number	3544-24-9
PubChem ID	1645
InChi Key	GSCPDZHWVNUUFI-UHFFFAOYSA-N
Smiles	NC(=O)C1=CC=CC(N)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water		100

Preparing Stock Solutions

The following data is based on the product molecular weight 136.15.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	7.34 mL	36.72 mL	73.45 mL
5 mM	1.47 mL	7.34 mL	14.69 mL
10 mM	0.73 mL	3.67 mL	7.34 mL
50 mM	0.15 mL	0.73 mL	1.47 mL

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Reconstitution Calculator

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References

References are publications that support the biological activity of the product.

Cuzzocrea Beneficial effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase in a rat model of splanchnic artery occlusion and reperfusion. Br.J.Pharmacol. 1997 PMID: 9249240
Malorni 3-Aminobenzamide protects cells from UV-B-induced apoptosis by acting on cytoskeleton and substrate adhesion. Biochem.Biophys.Res.Commun. 1995 PMID: 7864864

Citations for 3-Aminobenzamide (1)

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Citations are publications that use Bio-Techne products. Selected citations for 3-Aminobenzamide include:

Pakula et al. (2019) The Epithelial-Mesenchymal Transition Initiated by Malignant Ascites Underlies the Transmesothelial Invasion of Ovarian Cancer Cells. Int J Mol Sci. 20
PMID: 30609691

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