Tocris Bioscience a Bio-Techne Brand
Key Product Details
|Description:||Potent melatonin agonist|
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Citations for 2-Phenylmelatonin (3)
Citations are publications that use Bio-Techne products. Selected citations for 2-Phenylmelatonin include:
Stauch et al.
Structural basis of ligand recognition at the human MT1 melatonin receptor
Johansson et al.
XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity.
Akoume et al.
A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression.
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Customer Reviews for 2-Phenylmelatonin (1)
Species: HumanAssay Type: In VitroAfter trying many other melatonin receptor ligands, this has become our gold standard for stabilizing MT1 and MT2 melatonin GPCRs for in vitro studies. Given its high potency, relatively low micromolar concentrations are sufficient to achieve the desired effect. We found that it sufficiently stabilizes MTRs for crystallization purposes. Additionally, in cell based GPCR activity assays, it is able to achieve an efficacy as high as, or higher, than the endogenous ligand melatonin. Highly recommended if you value maximum stabilization and/or efficacyDissolves well in DMSO
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