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Bio-Techne includes Tocris Bioscience | Catalog # 0680

Potent melatonin agonist
Potent melatonin agonist

Key Product Details

Description: Potent melatonin agonist
Chemical Name: N-[2-(5-Methoxy-2-phenylindol-3-yl)ethyl]acetamide
Purity: ≥98% (HPLC)
Molecular Weight: 308.38

Citations for 2-Phenylmelatonin (3)

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Customer Reviews for 2-Phenylmelatonin (1)

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  • Highly recommended for in vitro stabilization and crystallization of melatonin receptors
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    After trying many other melatonin receptor ligands, this has become our gold standard for stabilizing MT1 and MT2 melatonin GPCRs for in vitro studies. Given its high potency, relatively low micromolar concentrations are sufficient to achieve the desired effect. We found that it sufficiently stabilizes MTRs for crystallization purposes. Additionally, in cell based GPCR activity assays, it is able to achieve an efficacy as high as, or higher, than the endogenous ligand melatonin. Highly recommended if you value maximum stabilization and/or efficacy
    Dissolves well in DMSO

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Product Documents for 2-Phenylmelatonin

Certificate of Analysis

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