2-Methylthioadenosine triphosphate tetrasodium salt

Name: 2-Methylthioadenosine triphosphate tetrasodium salt
Brand: Tocris Bioscience
SKU: 1062

Tocris Bioscience, part of Bio-Techne | Catalog # 1062

Citations (8)

COA / SDS

Non-selective P2 agonist

Key Product Details

Description:	Non-selective P2 agonist
Alternative Names:	2-Methylthio-ATP
Chemical Name:	2-Methylthioadenosine-5'-triphosphate tetrasodium salt
Purity:	≥98% (HPLC)
Molecular Weight:	641.2

View Full Technical Details for 2-Methylthioadenosine triphosphate tetrasodium salt

Technical Data
Citations

Biological Activity for 2-Methylthioadenosine triphosphate tetrasodium salt

2-Methylthioadenosine triphosphate tetrasodium salt is a P2 purinoceptor agonist.

Technical Data for 2-Methylthioadenosine triphosphate tetrasodium salt

M. Wt	641.2
Formula	C₁₁H₁₄N₅Na₄O₁₃P₃S
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	100020-57-3
PubChem ID	16218831
InChi Key	UEEFBRHXFDJPTA-KWIZKVQNSA-J
Smiles	NC1=C2C(N([C@@H]3O[C@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)[C@@H](O)[C@H]3O)C=N2)=NC(SC)=N1.[Na+].[Na+].[Na+].[Na+]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for 2-Methylthioadenosine triphosphate tetrasodium salt

Solubility

Soluble in water (supplied pre-dissolved at a concentration of 10mM)

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References for 2-Methylthioadenosine triphosphate tetrasodium salt

References are publications that support the biological activity of the product.

McMurray Purinoceptor subtypes mediating contraction and relaxation of marmoset urinary bladder smooth muscle. Br.J.Pharmacol. 1998 PMID: 9605564
Cusack Specific but non-competitive inhibition by 2-alkylthioanalogues of adenosine 5'-monophosphate and adenosine 5'-triphosphate of human platelet aggregation induced by adenosine 5'-diphosphate. Br.J.Pharmacol. 1982 PMID: 7186826
Khakh International Union of Pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunits. Pharmacol.Rev. 2001 PMID: 11171941
Burnstock Studies on the stereoselectivity of the P₂-purinoreceptor. Br.J.Pharmacol. 1983 PMID: 6317121