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1400W dihydrochloride

Tocris Bioscience a Bio-Techne Brand

iNOS Inhibitors Small Molecule
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Key Product Details

Description: Potent, highly selective iNOS inhibitor
Chemical Name: N-[[3-(Aminomethyl)phenyl]methyl]-ethanimidamide dihydrochloride
Purity: ≥99% (HPLC)
Molecular Weight: 250.17

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Citations for 1400W dihydrochloride (9)

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Customer Reviews for 1400W dihydrochloride (3)

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  • Inhibition of iNOS by 1400W
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: primary BMDM
    Macrophages were treated with LPS (10 ng/mL) and IFN-y (20 ng/mL) for 24h in the presence of 1400W (100 uM)
    1400W dihydrochloride Serum 1415
  • 1400W inhibits iNOS expression induced by LPS
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: Macrophages
    RAW macrophages were treated with 200 ng/ml LPS alone or after pre-treatment with 1 μM 1400W (30 min pre-incubation) for 8 h to follow iNOS expression using Western blot. LPS treatment elevated iNOS expression while 1400W pretreatment significantly blunted this effect.
    1400W dihydrochloride Serum 1415
  • iNOS inhibitor
    Name: Anonymous
    Species: Mouse
    Assay Type: Ex Vivo
    Used as iNOS inhibitor for organ bath experiments with rat and mouse aorta
    Good solubility and stability

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Product Documents for 1400W dihydrochloride

Certificate of Analysis

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