NVS-CECR2-1
Tocris Bioscience, part of Bio-Techne | Catalog # 5744
Potent and selective CECR2 inhibitor
Key Product Details
Description
Potent and selective CECR2 inhibitor
Product Description
NVS-CECR2-1 is a potent and selective CECR2 (cat eye syndrome chromosome region, candidate 2) inhibitor (IC50 = 47 nM). Selective for CECR2 over a panel of bromodomains.A concentration of 1 μM is recommended for use in cellular assays.
Licensing Information
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the NVS-CECR2-1 probe summary on the SGC website.Product Specifications
Molecular Weight
495.68
Formula
C27H37N5O2S
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
N-Cyclopropyl-2-(propylsulfonyl)-6-(1-(2,2,6,6-tetramethylpiperidin-4-yl)-1H-indol-5-yl)pyrimidin-4-amine
CAS Number
1992047-61-6
PubChem ID
117072550
InChI Key
XVECNLUKQDKOST-UHFFFAOYSA-N
SMILES
CC(C1)(C)NC(C)(C)CC1N2C=CC3=C2C=CC(C4=NC(S(=O)(CCC)=O)=NC(NC5CC5)=C4)=C3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 49.57 | 100 |
Preparing Stock Solutions
for NVS-CECR2-1
The following data is based on the product molecular weight 495.68
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.02 mL | 10.09 mL | 20.17 mL |
| 5 mM | 0.40 mL | 2.02 mL | 4.03 mL |
| 10 mM | 0.20 mL | 1.01 mL | 2.02 mL |
| 50 mM | 0.04 mL | 0.20 mL | 0.40 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Product Specific Notices for NVS-CECR2-1
For research use only
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