Deferoxamine mesylate
Tocris Bioscience, part of Bio-Techne | Catalog # 5764
Iron chelator; also hypoxia mimetic and neuroprotectant
Key Product Details
Description
Iron chelator; also hypoxia mimetic and neuroprotectant
Product Description
Deferoxamine mesylate is an iron chelator. Also hypoxia mimetic and inhibitor of ferroptosis. Has neuroprotective effects in animal models of stroke, traumatic brain injury and neurodegenerative diseases.Product Specifications
Molecular Weight
656.79
Formula
C25H48N6O8.CH4O3S
Storage
Store at -20°C
Chemical Name
N4-[5-[[4-[[5-(Acetylhydroxyamino)pentyl]amino-1,4-dioxobutyl]hydroxyamino]pentyl]-N1-(5-aminopentyl)-N1-hydroxybutanediamide methanesulfonate
CAS Number
138-14-7
PubChem ID
62881
InChI Key
IDDIJAWJANBQLJ-UHFFFAOYSA-N
SMILES
ON(C(CCC(NCCCCCN(C(CCC(NCCCCCN(O)C(C)=O)=O)=O)O)=O)=O)CCCCCN.CS(=O)(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 65.68 | 100 |
Preparing Stock Solutions
for Deferoxamine mesylate
The following data is based on the product molecular weight 656.79
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.52 mL | 7.61 mL | 15.23 mL |
| 5 mM | 0.30 mL | 1.52 mL | 3.05 mL |
| 10 mM | 0.15 mL | 0.76 mL | 1.52 mL |
| 50 mM | 0.03 mL | 0.15 mL | 0.30 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Kosyakovsky Quantifying intranasally administered deferoxamine in rat brain tissue with mass spectrometry. ACS Chem.Neurosci. 2019 PMID: 31573798
- Chau Identification of novel small molecule inhibitors of hypoxia-inducible factor-1 that differentially block hypoxia-inducible factor-1 activity and hypoxia-inducible factor-1alpha induction in response to hypoxic stress and growth factors. Cancer Res. 2005 PMID: 15930314
Product Specific Notices for Deferoxamine mesylate
For research use only
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