Simple Plex Control for Human/Mouse/Rat/NHP GDF-8
R&D Systems, part of Bio-Techne | Catalog # 898090
Control for use with Human/Mouse/Rat/NHP GDF-8 Simple Plex Assay Cartridge Kit.
Key Product Details
Species
Human, Mouse, Rat, Non-human Primate
Product Summary for Simple Plex Control for Human/Mouse/Rat/NHP GDF-8
INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human/mouse/rat GDF-8 concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.”
Formulation, Preparation, and Storage
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
Background: GDF-8/Myostatin
GDF-8/Myostatin is a secreted protein that is expressed in developing and adult skeletal muscle. It controls myoblast proliferation and is a potent negative regulator of skeletal muscle mass. It is upregulated in mechanically-stressed cardiomyocytes and induces the skeletal muscle wasting which is common in heart failure. The GDF-8 propeptide is cleaved from GDF-8 but remains associated and functions as an inhibitor of mature GDF-8. GDF-8 activity can also be inhibited through its association with Follistatin, FLRG, Decorin, or GASP-1. Active GDF-8 signals through a receptor complex containing Activin RIIB and either Activin RIB/ALK-4 or TGF-beta RI/ALK-5.
Long Name
Growth Differentiation Factor 8
Alternate Names
GDF8, MSLHP, MSTN, Myostatin
Gene Symbol
MSTN
Additional GDF-8/Myostatin Products
Product Documents for Simple Plex Control for Human/Mouse/Rat/NHP GDF-8
Product Specific Notices for Simple Plex Control for Human/Mouse/Rat/NHP GDF-8
For research use only
Loading...
Loading...
Loading...