Cyclofenil
Tocris Bioscience, part of Bio-Techne | Catalog # 3999
Selective estrogen receptor modulator (SERM)
Discontinued Product
3999 has been discontinued.
View all Estrogen and Related Receptor Modulators products.
Key Product Details
Description
Selective estrogen receptor modulator (SERM)
Product Description
Non-steroidal selective estrogen receptor modulator (SERM). Displays higher affinity for estrogen receptor β (ERβ) than for ERα.Product Specifications
Molecular Weight
364.43
Formula
C23H24O4
Storage
Store at +4°C
Purity
≥99% (HPLC)
Chemical Name
4,4'-(Cyclohexylidenemethylene)bisphenol 1,1'-diacetate
CAS Number
2624-43-3
PubChem ID
2898
InChI Key
GVOUFPWUYJWQSK-UHFFFAOYSA-N
SMILES
CC(OC(C=C3)=CC=C3/C(C2=CC=C(OC(C)=O)C=C2)=C1/CCCCC1)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 3.64 | 10 |
Preparing Stock Solutions
for Cyclofenil
The following data is based on the product molecular weight 364.43
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.44 mL | 137.20 mL | 274.40 mL |
| 0.5 mM | 5.49 mL | 27.44 mL | 54.88 mL |
| 1 mM | 2.74 mL | 13.72 mL | 27.44 mL |
| 5 mM | 0.55 mL | 2.74 mL | 5.49 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Seo Fluorine-substituted cyclofenil derivatives as estrogen receptor ligands: synthesis and structure-affinity relationship study of potential PET agents for imaging estrogen receptors in breast cancer. J.Med.Chem. 2006 PMID: 16610793
- Kieser Characterization of the pharmacore properties of novel selective estrogen receptor downregulators (SERDs). J.Med.Chem. 2010 PMID: 20334372
Product Specific Notices for Cyclofenil
For research use only
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