Recombinant Human VPS24 His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-72349

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NBP1-72349-0.5mg
NBP1-72349-100ug
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Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all VPS24 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-222 of Human VPS24

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGLFGKTQEK PPKELVNEWS LKIRKEMRVV DRQIRDIQRE EEKVKRSVKD AAKKGQKDVC IVLAKEMIRS RKAVSKLYAS KAHMNSVLMG MKNQLAVLRV AGSLQKSTEV MKAMQSLVKI PEIQATMREL SKEMMKAGII EEMLEDTFES MDDQEEMEEE AEMEIDRILF EITAGALGKA PSKVTDALPE PEPPGAMAAS EDEEEEEEAL EAMQSRLATL RS

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

27.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human VPS24 His Protein

SDS-PAGE: Recombinant Human VPS24 His Protein [NBP1-72349]

SDS-PAGE: Recombinant Human VPS24 His Protein [NBP1-72349]

SDS-Page: Recombinant Human VPS24 His Protein [NBP1-72349] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

Formulation, Preparation and Storage

NBP1-72349
Formulation 20 mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1 M NaCl, 1 mM DTT
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: VPS24

VPS24, also known as Charged multivesicular body protein 3(CHMP3), belongs to the vacuolar sorting protein family and function as chromatin modifying proteins. It associates directly with CHMP2 and CHMP4 for the disassembly of ESCRT-III complex in an ATP-dependent manner. During HIV-1 infection, the virus uses the ESCRT-III complex to mediate budding and exocytosis of viral proteins. Overexpression of VPS24 strongly inhibits HIV-1 release. Recombinant human VPS24 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Alternate Names

CGI-149, CHMP325.1 protein, Chromatin-modifying protein 3, hVps24, member 3,25.1, NEDFFLJ38114, vacuolar protein sorting 24 (yeast), vacuolar protein sorting 24 homolog (S. cerevisiae)

Gene Symbol

CHMP3

Additional VPS24 Products

Product Documents for Recombinant Human VPS24 His Protein

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Recombinant Human VPS24 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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