Recombinant Human TRAM/TICAM2 His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-78901

Novus Biologicals, part of Bio-Techne
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Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all TRAM/TICAM2 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-235 of Human TRAM/TICAM2

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMGIGKS KINSCPLSLS WGKRHSVDTS PGYHESDSKK SEDLSLCNVA EHSNTTEGPT GKQEGAQSVE EMFEEEAEEE VFLKFVILHA EDDTDEALRV QNLLQDDFGI KPGIIFAEMP CGRQHLQNLD DAVNGSAWTI LLLTENFLRD TWCNFQFYTS LMNSVNRQHK YNSVIPMRPL NNPLPRERTP FALQTINALE EESRGFPTQV ERIFQESVYK TQQTIWKETR NMVQRQFIA

Purity

>85%, by SDS-PAGE

Predicted Molecular Mass

29.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human TRAM/TICAM2 His Protein

SDS-PAGE: Recombinant Human TRAM/TICAM2 His Protein [NBP1-78901]

SDS-PAGE: Recombinant Human TRAM/TICAM2 His Protein [NBP1-78901]

SDS-Page: Recombinant Human TRAM/TICAM2 Protein [NBP1-78901] - 15% SDS-PAGE (3ug)

Formulation, Preparation and Storage

NBP1-78901
Formulation 20 mM Tris-HCl buffer (pH 8.0), 1 mM DTT, 10% glycerol, 0.1 M NaCl
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRAM/TICAM2

Toll TIR domain-containing adapter molecule 2, also known as TICAM2, is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TICAM-2, a cytoplasmic protein, physically bridges TLR4 and TICAM-1 and functionally transmits LPS-TLR4 signaling to TICAM-1, which in turn activates IRF-3. It is involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB. Recombinant human TICAM2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Long Name

TRIF-related Adapter Molecule

Alternate Names

TICAM2, TIRAP3, TIRP, Trif

Gene Symbol

TICAM2

Additional TRAM/TICAM2 Products

Product Documents for Recombinant Human TRAM/TICAM2 His Protein

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Recombinant Human TRAM/TICAM2 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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