Recombinant Human TIP30 His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-50847

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NBP1-50847-0.1mg
NBP1-50847-0.5mg
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Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all TIP30 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-242 of Human TIP30

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MAETEALSKL REDFRMQNKS VFILGASGET GRVLLKEILE QGLFSKVTLI GRRKLTFDEE AYKNVNQEVV DFEKLDDYAS AFQGHDVGFC CLGTTRGKAG AEGFVRVDRD YVLKSAELAK AGGCKHFNLL SSKGADKSSN FLYLQVKGEV EAKVEELKFD RYSVFRPGVL LCDRQESRPG EWLVRKFFGS LPDSWARGHS VPVVTVVRAM LNNVVRPRDK QMELLENKAI HDLGKAHGSL KP

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

29.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human TIP30 His Protein

SDS-PAGE: Recombinant Human TIP30 His Protein [NBP1-50847]

SDS-PAGE: Recombinant Human TIP30 His Protein [NBP1-50847]

SDS-Page: Recombinant Human TIP30 Protein [NBP1-50847] - 15 % SDS-PAGE (3ug)

Formulation, Preparation and Storage

NBP1-50847
Formulation 20 mM Tris-HCl buffer (pH 8.0), 10% glycerol, 1 mM DTT
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TIP30

HTATIP2, also known as TIP30, is a member of the short-chain dehydrogenases/reductases (SDR) family. It acts as a tumor suppressor participating in metabolic suppression, inhibition of angiogenesis and induces the expression of apoptosis related genes Bad and Siva. HTATIP2 interacts with the activation domain of HIV-1 TAT and enhances its transcription by phosphorylating RNA polymerase II (Pol II). Defects in This protein are associated with hepatocellular carcinomas and apoptotic resistant tumor cells, suggesting a potential use for HTATIP2 in antitumor therapy. Recombinant human HTATIP2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques

Alternate Names

30 kDa HIV-1 TAT-interacting protein, CC3oxidoreductase HTATIP2, EC 1.1.1, EC 1.1.1.-, FLJ26963, HIV-1 Tat interactive protein 2, 30 kDa, HIV-1 Tat interactive protein 2, 30kDa, HIV-1 TAT-interactive protein 2, SDR44U1, Tat-interacting protein (30kD), TIP30short chain dehydrogenase/reductase family 44U, member 1

Gene Symbol

HTATIP2

Additional TIP30 Products

Product Documents for Recombinant Human TIP30 His Protein

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Recombinant Human TIP30 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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