Recombinant Human SMNDC1 His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-50891

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NBP1-50891-0.25mg
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Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all SMNDC1 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-238 of Human SMNDC1

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MSEDLAKQLA SYKAQLQQVE AALSGNGENE DLLKLKKDLQ EVIELTKDLL STQPSETLAS SDSFASTQPT HSWKVGDKCM AVWSEDGQCY EAEIEEIDEE NGTAAITFAG YGNAEVTPLL NLKPVEEGRK AKEDSGNKPM SKKEMIAQQR EYKKKKALKK AQRIKELEQE REDQKVKWQQ FNNRAYSKNK KGQVKRSIFA SPESVTGKVG VGTCGIADKP MTQYQDTSKY NVRHLMPQ

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

28.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human SMNDC1 His Protein

SDS-PAGE: Recombinant Human SMNDC1 His Protein [NBP1-50891]

SDS-PAGE: Recombinant Human SMNDC1 His Protein [NBP1-50891]

SDS-Page: Recombinant Human SMNDC1 Protein [NBP1-50891] - 15 % SDS-PAGE (3ug)

Formulation, Preparation and Storage

NBP1-50891
Formulation 20 mM Tris-HCl buffer (pH8.0), 10% glycerol, 1 mM DTT, 100 mM NaCl
Preservative No Preservative
Concentration 0.5 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SMNDC1

SMNDC1 (survival motor neuron domain containing 1) is an essential splicing factor required for spliceosome assembly that belongs to the SMN family. It contains one Tudor domain with significant similarity to SMN (Survival Motor Neuron) and is expressed in skeletal muscle, pancreas and heart, localizing to Cajal bodies and nuclear speckles. Mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. Recombinant human SMNDC1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

SMNRSMN-related protein, SPF30splicing factor 30, survival of motor neuron-related, survival motor neuron domain containing 1,30 kDa splicing factor SMNrp, Survival motor neuron domain-containing protein 1, survival of motor neuron-related-splicing factor 30

Gene Symbol

SMNDC1

Additional SMNDC1 Products

Product Documents for Recombinant Human SMNDC1 His Protein

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Recombinant Human SMNDC1 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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