Recombinant Mouse SCF Protein Best Seller

Name: Recombinant Mouse SCF Protein
Brand: R&D Systems
SKU: 455-MC
Rating: 4 (5 reviews)

Catalog # 455-MC | R&D Systems, Inc. a Bio-Techne Brand

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Citations (177)

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Setting the standard in quality research reagents

Key Product Details

Source:	E. coli
Accession #:	Q78ED8
Applications:	Bioactivity

View Full Technical Details for Recombinant Mouse SCF Protein

Technical Data
Citations (177) / Reviews (5)

Product Specifications for Recombinant Mouse SCF Protein

Source	E. coli-derived mouse SCF/c-kit Ligand protein Lys26-Ala189, with an N-terminal Met
Purity	>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Endotoxin level	<0.10 EU per 1 μg of the protein by the LAL method.
N-terminal sequence Analysis	Met
Predicted Molecular Mass	18.6 kDa
SDS-PAGE	18.6 kDa
Activity	Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. Kitamura, T. et al. (1989) J. Cell Physiol. 140:323. The ED₅₀ for this effect is 2.5-10 ng/mL.

Scientific Data Examples for Recombinant Mouse SCF Protein

	Recombinant Mouse SCF Protein Bioactivity Recombinant Mouse SCF/c-kit Ligand (Catalog # 455-MC) stimulates cell proliferation of the TF-1 human erythroleukemic cell line. The ED₅₀ for this effect is 2.5-10 ng/mL.
	Recombinant Mouse SCF Protein SDS-PAGE 1 μg/lane of Recombinant Mouse SCF/c-kit was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 19 kDa.

Formulation, Preparation and Storage

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

455-MC

Carrier

Formulation	Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Reconstitution	Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage:	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

455-MC/CF

Carrier Free

Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	Reconstitute at 100 μg/mL in sterile PBS.
Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage:	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: SCF/c-kit Ligand

Stem cell factor (SCF), also known as c-kit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28 - 40 kDa type I transmembrane glycoprotein (1). It promotes the survival, differentiation, and mobilization of multiple cell types including myeloid, erythroid, megakaryocytic, lymphoid, germ cell, and melanocyte progenitors (1 - 7). SCF is a primary growth and activation factor for mast cells and eosinophils (8). Mature mouse SCF consists of a 189 amino acid (aa) extracellular domain (ECD), a 23 aa transmembrane segment, and a 36 aa cytoplasmic tail (9). The ECD shows both N-linked and O-linked glycosylation (10). Proteolytic cleavage at two alternate sites in the extracellular juxtamembrane region releases a 25 kDa soluble molecule which is comparable to the only form produced by Steel-dickie mutant mice (11, 12). An alternately spliced isoform of mouse SCF lacks 28 aa that encompasses the primary proteolytic recognition site (13). Within the ECD of the short isoform (corresponding to this recombinant protein), mouse SCF shares 93% aa sequence identity with rat SCF and 72% - 75% with canine, feline, and human SCF. Rat SCF is active on mouse and human cells, but human SCF is only weakly active on mouse cells (14). Noncovalent dimers of transmembrane or soluble SCF interact with the receptor tyrosine kinase SCF R/c-kit to trigger receptor dimerization and signaling (15). SCF assists in the recovery of cardiac function following myocardial infarction by increasing the number of cardiomyocytes and vascular channels (16).

Item	Value
References	Ashman, L.K. (1999) Int. J. Biochem. Cell Biol. 31:1037. Sette, C. et al. (2000) Int. J. Dev. Biol. 44:599. Yoshida, H. et al. (2001) J. Invest. Dermatol. Symp. Proc. 6:1. Erlandsson, A. et al. (2004) Exp. Cell Res. 301:201. Kapur, R. et al. (2002) Blood 100:1287. Wang, C.-H. et al. (2007) Arterioscler. Thromb. Vasc. Biol. 27:540. Bashamboo, A. et al. (2006) J. Cell Sci. 119:3039. Reber, L. et al. (2006) Eur. J. Pharmacol. 533:327. Huang, E. et al. (1990) Cell 63:225. Arakawa, T. et al. (1991) J. Biol. Chem. 266:18942. Majumdar, M.K. et al. (1994) J. Biol. Chem. 269:1237. Brannan, C.I. et al. (1991) Proc. Natl. Acad. Sci. 88:4671. Flanagan, J.G. et al. (1991) Cell 64:1025. Martin, F.H. et al. (1990) Cell 63:203. Lemmon, M.A. et al. (1997) J. Biol. Chem. 272:6311. Kanellakis, P. et al. (2006) Cardiovasc. Res. 70:117.
Long Name	Stem Cell Factor
Entrez Gene IDs	4254 (Human); 17311 (Mouse); 60427 (Rat); 403507 (Canine); 493937 (Feline)
Alternate Names	DCUA, DFNA69, DKFZp686F2250, FPH2, FPHH, KIT ligand, KITLG, KL-1, Kitl, MGF, MGFSHEP7, Mast cell growth factor, SCF, SCFStem cell factor, SFc-Kit ligand, SHEP7, SLF, c-kit Ligand, familial progressive hyperpigmentation 2, steel factor

Citations for Recombinant Mouse SCF Protein (177)

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Citations are publications that use Bio-Techne products. Selected citations for Recombinant Mouse SCF Protein include:

Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Williams et al. (2023-05-27), Nore1 inhibits age-associated myeloid lineage skewing and clonal hematopoiesis, but facilitates termination of emergency (stress) granulopoiesis The Journal of biological chemistry
PMID: 37247756
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Lee et al. (2023-05-13), Endothelial cell-derived stem cell factor promotes lipid accumulation through c-Kit-mediated increase of lipogenic enzymes in brown adipocytes Nature communications
PMID: 37179330
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

H Huang et al. (2023-03-30), The RNA-binding protein hnRNP F is required for the germinal center B cell response Nature Communications, 2023-014(1):1731.
PMID: 36997512
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

X Cui et al. (2023-03-16), Latexin regulates sex dimorphism in hematopoiesis via gender-specific differential expression of microRNA 98-3p and thrombospondin 1 Cell Reports, 2023-042(3):112274.
PMID: 36933218
Species: Human
Sample Types: Transfected Whole Cells
Applications: Bioassay

M Shono et al. (2023-02-23), Induction of primordial germ cell-like cells from common marmoset embryonic stem cells by inhibition of WNT and retinoic acid signaling Scientific Reports, 2023-013(1):3186.
PMID: 36823310
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

X Liu et al. (2022-12-01), IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia Embo Molecular Medicine, 2022-10(0):e15631.
PMID: 36453131
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

M Uslu et al. (2022-07-11), Competitive inhibition of IL-2/IL-2R has a dual effect on HSC ex vivo expansion and IL-2R (CD25) content International immunopharmacology, 2022-0110(0):109035.
PMID: 35834953
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Y Hayashi et al. (2022-05-10), MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis Cell Reports, 2022-039(6):110805.
PMID: 35545056
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

J Jeong et al. (2022-04-26), BAP1 shapes the bone marrow niche for lymphopoiesis by fine-tuning epigenetic profiles in endosteal mesenchymal stromal cells Cell Death and Differentiation, 2022-00(0).
PMID: 35473985
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Q Zhang et al. (2022-02-08), Mosaic loss of chromosome Y promotes leukemogenesis and clonal hematopoiesis JCI Insight, 2022-07(3).
PMID: 35132955
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

BE Thacker et al. (2022-01-14), Multiplex genome editing of mammalian cells for producing recombinant heparin Metabolic engineering, 2022-00(0).
PMID: 35038554
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

R Deshycka et al. (2021-11-03), Engineered red blood cells carrying PCSK9 inhibitors persistently lower LDL and prevent obesity PLoS ONE, 2021-116(11):e0259353.
PMID: 34731223
Species: Rabbit
Sample Types: Whole Cells
Applications: Bioassay

T Kobayashi et al. (2021-10-12), Tracing the emergence of primordial germ cells from bilaminar disc rabbit embryos and pluripotent stem cells Cell Reports, 2021-137(2):109812.
PMID: 34644585
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

HZ Guo et al. (2021-10-08), Leukemic progenitor cells enable immunosuppression and post-chemotherapy relapse via IL-36-inflammatory monocyte axis Science Advances, 2021-17(41):eabg4167.
PMID: 34623912
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

SR Naidu et al. (2021-10-01), Chromatin remodeling subunit BRM and valine regulate hematopoietic stem/progenitor cell function and self-renewal via intrinsic and extrinsic effects Leukemia, 2021-10(0).
PMID: 34599272
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Y Ishikura et al. (2021-09-07), Inï¿½vitro reconstitution of the whole male germ-cell development from mouse pluripotent stem cells Cell Stem Cell, 2021-00(0).
PMID: 34496297
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

C Zhao et al. (2021-08-27), Acute myeloid leukemia cell-derived extracellular vesicles carrying microRNA-548ac regulate hematopoietic function via the TRIM28/STAT3 pathway Cancer Gene Therapy, 2021-00(0).
PMID: 34453123
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

K Yamamoto et al. (2021-08-24), A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells Cell Reports, 2021-036(8):109576.
PMID: 34433054
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

N Ohashi et al. (2021-06-17), GLT1 gene delivery based on bone marrow-derived cells ameliorates motor function and survival in a mouse model of ALS Scientific Reports, 2021-011(1):12803.
PMID: 34140581
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

F Herbst et al. (2021-05-21), The balance between the intronic miR-342 and its host gene Evl determines hematopoietic cell fate decision Leukemia, 2021-00(0).
PMID: 34021250
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

J Lu et al. (2021-03-29), Declined miR-181a-5p expression is associated with impaired natural killer cell development and function with aging Aging Cell, 2021-00(0):e13353.
PMID: 33780118
Applications: Bioassay

AK Persaud et al. (2021-02-23), Facilitative lysosomal transport of bile acids alleviates ER stress in mouse hematopoietic precursors Nature Communications, 2021-012(1):1248.
PMID: 33623001
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

X Wang et al. (2021-02-19), Formative pluripotent stem cells show features of epiblast cells poised for gastrulation Cell Research, 2021-00(0).
PMID: 33608671
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

S Takashima et al. (2021-01-15), Myocyte-specific enhancer factor 2c triggers transdifferentiation of adipose tissue-derived stromal cells into spontaneously beating cardiomyocyte-like cells Scientific Reports, 2021-011(1):1520.
PMID: 33452355
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

RA Cardenas et al. (2021-01-08), SNAP23 is essential for platelet and mast cell development and required in connective tissue mast cells for anaphylaxis The Journal of Biological Chemistry, 2021-0296(0):100268.
PMID: 33837726
Species: Transgenic Mouse
Sample Types: Spheroid
Applications: Bioassay

AE Engler et al. (2020-12-29), Airway-Associated Macrophages in Homeostasis and Repair Cell Reports, 2020-133(13):108553.
PMID: 33378665
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Y Hong et al. (2020-12-09), Authentication of Primary Murine Cell Lines by a Microfluidics-Based Lab-On-Chip System Biomedicines, 2020-18(12).
PMID: 33317212
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

K Spinler et al. (2020-11-26), A stem cell reporter based platform to identify and target drug resistant stem cells in myeloid leukemia Nat Commun, 2020-111(1):5998.
PMID: 33243988
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

T Trinh et al. (2020-11-07), Leptin receptor, a surface marker for a subset of highly engrafting long-term functional hematopoietic stem cells Leukemia, 2020-10(0).
PMID: 33159180
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

M Girotra et al. (2020-11-03), In Vivo Pre-Instructed HSCs Robustly Execute Asymmetric Cell Divisions In Vitro Int J Mol Sci, 2020-121(21).
PMID: 33153113
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

M Wada et al. (2020-09-20), Exï¿½Vivo Gene Therapy Treats Bone Complications of Mucopolysaccharidosis Type II Mouse Models through Bone Remodeling Reactivation Mol Ther Methods Clin Dev, 2020-019(0):261-274.
PMID: 33102618
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

H Huang et al. (2020-08-31), Covalent inhibition of NSD1 histone methyltransferase Nat. Chem. Biol., 2020-00(0).
PMID: 32868895
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay, Cell Culture

V Peng et al. (2020-08-19), E proteins orchestrate dynamic transcriptional cascades implicated in the suppression of the differentiation of group 2 innate lymphoid cells J. Biol. Chem., 2020-00(0).
PMID: 32817168
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

C Cho et al. (2020-08-17), Cancer-associated fibroblasts downregulate type I interferon receptor to stimulate intratumoral stromagenesis Oncogene, 2020-00(0).
PMID: 32807917
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

NV Bogert et al. (2020-08-13), A novel approach to genetic engineering of T-cell subsets by hematopoietic stem cell infection with a bicistronic lentivirus Sci Rep, 2020-010(1):13740.
PMID: 32792615
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

L Garcia-Per et al. (2020-03-31), Successful Preclinical Development of Gene Therapy for Recombinase-Activating Gene-1-Deficient SCID Mol Ther Methods Clin Dev, 2020-017(0):666-682.
PMID: 32322605
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

C Yamashiro et al. (2020-03-30), Generation of human oogonia from induced pluripotent stem cells in culture Nat Protoc, 2020-015(4):1560-1583.
PMID: 32231324
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

S Kreutmair et al. (2020-03-17), Existence of reprogrammed lymphoma stem cells in a murine ALCL-like model Leukemia, 2020-00(0).
PMID: 32203142
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A Yoshimi et al. (2020-02-12), Genetic basis for iMCD-TAFRO Oncogene, 2020-00(0).
PMID: 32051554
Species: Mouse
Sample Types: Plasma
Applications: Multiplex Standard

JM Bertho et al. (2019-12-27), Hto, Tritiated Amino Acid Exposure and External Exposure Induce Differential Effects on Hematopoiesis and Iron Metabolism Sci Rep, 2019-19(1):19919.
PMID: 31882739
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

T Fukushima et al. (2019-12-17), Discrimination of Dormant and Active Hematopoietic Stem Cells by G0 Marker Reveals Dormancy Regulation by Cytoplasmic Calcium Cell Rep, 2019-129(12):4144-4158.e7.
PMID: 31851939
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

S Nair et al. (2019-07-03), Adult stem cell deficits drive Slc29a3 disorders in mice Nat Commun, 2019-010(1):2943.
PMID: 31270333
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

XU Haiqian et al. (2019-06-27), Adipose derived stem cells promote tumor metastasis in breast Cancer cells by stem cell factor inhibition of miR20b Cell. Signal., 2019-062(0):109350.
PMID: 31254605
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

R Magadmi et al. (2019-06-18), Secretion of Mast Cell Inflammatory Mediators Is Enhanced by CADM1-Dependent Adhesion to Sensory Neurons Front Cell Neurosci, 2019-013(0):262.
PMID: 31275114
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay

ML Capitano et al. (2019-05-20), Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signaling J. Clin. Invest., 2019-0130(0):2555-2570.
PMID: 31107242
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

YL Chang et al. (2019-05-14), Lipocalin 2: A New Antimicrobial in Mast Cells Int J Mol Sci, 2019-020(10).
PMID: 31091692
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

SK Nandakumar et al. (2019-05-09), Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis Elife, 2019-08(0).
PMID: 31070582
Species: Mouse
Sample Types: cell culture
Applications: cell culture media

MJ Delás et al. (2019-04-16), lncRNA Spehd Regulates Hematopoietic Stem and Progenitor Cells and Is Required for Multilineage Differentiation Cell Rep, 2019-027(3):719-729.e6.
PMID: 30995471
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

S Mayers et al. (2019-04-15), Establishment of an erythroid progenitor cell line capable of enucleation achieved with an inducible c-Myc vector BMC Biotechnol., 2019-019(1):21.
PMID: 30987611
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

C Li et al. (2019-04-11), Homoharringtonine exhibits potent anti-tumor effect and modulates DNA epigenome in acute myeloid leukemia by targeting SP1/TET1/5hmC Haematologica, 2019-00(0).
PMID: 30975912
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

N Vannini et al. (2019-03-07), The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance Cell Stem Cell, 2019-024(3):405-418.e7.
PMID: 30849366
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

AD Senft et al. (2019-03-06), Genetic dissection of Nodal and Bmp signalling requirements during primordial germ cell development in mouse Nat Commun, 2019-010(1):1089.
PMID: 30842446
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

N Maio et al. (2019-02-14), Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis Haematologica, 2019-00(0).
PMID: 30765471
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

F Ribezzo et al. (2019-01-16), Rps14, Csnk1a1 and miRNA145/miRNA146a deficiency cooperate in the clinical phenotype and activation of the innate immune system in the 5q- syndrome Leukemia, 2019-00(0).
PMID: 30651631
W Fonseca et al. (2019-01-07), Group 2 innate lymphoid cells (ILC2) are regulated by stem cell factor during chronic asthmatic disease Mucosal Immunol, 2019-012(2):445-456.
PMID: 30617299
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

JE Choi et al. (2018-12-28), Botulinum toxin blocks mast cells and prevents rosacea like inflammation J. Dermatol. Sci., 2018-10(0).
PMID: 30658871
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

E Sanchez et al. (2018-12-18), Syntaxin 3, but not Syntaxin 4, is required for mast cell regulated exocytosis, where it plays a primary role mediating compound exocytosis J. Biol. Chem., 2018-10(0).
PMID: 30563839
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Z He et al. (2018-12-05), Mast cells are essential intermediaries in regulating IL-33/ST2 signaling for an immune network favorable to mucosal healing in experimentally inflamed colons Cell Death Dis, 2018-19(12):1173.
PMID: 30518915
Species: Mouse

Applications: Cell Culture

Y Kimizuka et al. (2018-11-12), Brief Exposure of Skin to Near-Infrared Laser Modulates Mast Cell Function and Augments the Immune Response J. Immunol., 2018-10(0).
PMID: 30420435
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

AD Senft et al. (2018-08-21), Combinatorial Smad2/3 Activities Downstream of Nodal Signaling Maintain Embryonic/Extra-Embryonic Cell Identities during Lineage Priming Cell Rep, 2018-024(8):1977-1985.e7.
PMID: 30134160
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

SK Sweeney et al. (2018-07-27), Tracking embryonic hematopoietic stem cells to the bone marrow: nanoparticle options to evaluate transplantation efficiency Stem Cell Res Ther, 2018-09(1):204.
PMID: 30053892
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Y Heshmati et al. (2018-07-25), The histone chaperone NAP1L3 is required for haematopoietic stem cell maintenance and differentiation Sci Rep, 2018-08(1):11202.
PMID: 30046127
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

H Tokuo et al. (2018-07-11), Myosin X is required for efficient melanoblast migration and melanoma initiation and metastasis Sci Rep, 2018-08(1):10449.
PMID: 29993000
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

P Wünsche et al. (2018-07-05), Mapping Active Gene-Regulatory Regions in Human Repopulating Long-Term HSCs Cell Stem Cell, 2018-023(1):132-146.e9.
PMID: 29979988
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

X Jin et al. (2018-06-14), Iron overload impairs normal hematopoietic stem and progenitor cells through reactive oxygen species and shortens survival in myelodysplastic syndrome mice Haematologica, 2018-00(0).
PMID: 29903757
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

SK Tasian et al. (2018-06-08), Mutation-specific signaling profiles and kinase inhibitor sensitivities of juvenile myelomonocytic leukemia revealed by induced pluripotent stem cells Leukemia, 2018-00(0).
PMID: 29884903
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

JP Sasine et al. (2018-06-07), Wild-type Kras expands and exhausts hematopoietic stem cells JCI Insight, 2018-03(11).
PMID: 29875320
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

M Reitz et al. (2018-06-05), Interleukin-9 promotes early mast cell-mediated expulsion of Strongyloides ratti but is dispensable for generation of protective memory Sci Rep, 2018-08(1):8636.
PMID: 29872093
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A Rasheed et al. (2018-05-08), Loss of the Liver X Receptors Disrupts the Balance of Hematopoietic Populations, With Detrimental Effects on Endothelial Progenitor Cells J Am Heart Assoc, 2018-07(10).
PMID: 29739800
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

HT Fang et al. (2018-04-18), Global H3.3 dynamic deposition defines its bimodal role in cell fate transition Nat Commun, 2018-09(1):1537.
PMID: 29670118
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

C Sahin et al. (2018-04-15), Bone Marrow-Derived Cells Trafficking to the Oviduct: Effect of Ischemia-Reperfusion Injury Reprod Sci, 2018-00(0):1933719118770.
PMID: 29658434
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

R Nagase et al. (2018-04-11), Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation J. Exp. Med., 2018-00(0).
PMID: 29643185
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

BA Gutierrez et al. (2018-03-29), Munc18-2, but not Munc18-1 or Munc18-3, controls compound and single-vesicle regulated exocytosis in mast cells J. Biol. Chem., 2018-00(0).
PMID: 29599294
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

JS Dahlin et al. (2018-03-27), A single cell hematopoietic landscape resolves eight lineage trajectories and defects in Kit mutant mice Blood, 2018-00(0).
PMID: 29588278
Species: Mouse
Sample Types: Whole Cells
Applications: Differentiation, Differentiation

R Ramachandr et al. (2018-03-23), A Study and Review of Effects of Botulinum Toxins on Mast Cell Dependent and Independent Pruritus Toxins (Basel), 2018-010(4).
PMID: 29570628
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

MA Cherian et al. (2018-03-14), An activating mutation of interferon regulatory factor 4 (IRF4) in adult T cell leukemia J. Biol. Chem., 2018-00(0).
PMID: 29540473
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

YY Wang et al. (2018-03-09), In vivo selection with lentiviral expression of Bcl2T69A/S70A/S87Amutant in hematopoietic stem cell-transplanted mice Gene Ther., 2018-00(0).
PMID: 29523881
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

H Wang et al. (2018-02-20), The E3 ubiquitin ligase Triad1 influences development of Mll-Ell-induced acute myeloid leukemia Oncogene, 2018-00(0).
PMID: 29459712
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Q Cai et al. (2018-02-13), Combinations of antioxidants and/or of epigenetic enzyme inhibitors allow for enhanced collection of mouse bone marrow hematopoietic stem cells in ambient air Blood Cells Mol. Dis., 2018-00(0).
PMID: 29422232
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

M Bachmann et al. (2018-01-31), An unexpected protective role of low affinity allergen-specific IgG via the inhibitory receptor Fc?RIIb J. Allergy Clin. Immunol., 2018-00(0).
PMID: 29391255
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

K Dai et al. (2018-01-29), Kbtbd2 inhibits the cytotoxic activity of immortalized NK cells through down-regulating mTOR signaling in a mouse hepatocellular carcinoma model Eur. J. Immunol., 2018-00(0).
PMID: 29331106
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

X Jiang et al. (2017-12-13), Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia Nat Commun, 2017-18(1):2099.
PMID: 29235481
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

NJ Huang et al. (2017-09-04), Genetically engineered red cells expressing single domain camelid antibodies confer long-term protection against botulinum neurotoxin Nat Commun, 2017-08(1):423.
PMID: 28871080
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

D Sainz de l et al. (2017-07-05), Metabolic Reprogramming, Autophagy, and Reactive Oxygen Species Are Necessary for Primordial Germ Cell Reprogramming into Pluripotency Oxid Med Cell Longev, 2017-02017(0):4745252.
PMID: 28757909
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Q Bernard et al. (2017-06-27), Interaction of primary mast cells with Borrelia burgdorferi (sensu stricto): role in transmission and dissemination in C57BL/6 mice Parasit Vectors, 2017-010(1):313.
PMID: 28655322
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Y Chen et al. (2017-06-12), MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia Cancer Cell, 2017-031(6):755-770.e6.
PMID: 28609655
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

T Maetzig et al. (2017-06-01), Lentiviral Fluorescent Genetic Barcoding for Multiplex Fate Tracking of Leukemic Cells Mol Ther Methods Clin Dev, 2017-06(0):54-65.
PMID: 28664166
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

H Ohta et al. (2017-05-30), In vitro expansion of mouse primordial germ cell-like cells recapitulates an epigenetic blank slate EMBO J., 2017-00(0).
PMID: 28559416
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

J Huang et al. (2017-05-12), Lentivector Iterations and Pre-Clinical Scale-Up/Toxicity Testing: Targeting Mobilized CD34(+) Cells for Correction of Fabry Disease Mol Ther Methods Clin Dev, 2017-05(0):241-258.
PMID: 28603745
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Y Zhao et al. (2017-05-09), Small molecule p300/catenin antagonist enhances hematopoietic recovery after radiation PLoS ONE, 2017-012(5):e0177245.
PMID: 28486541
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

S Shukla et al. (2017-04-10), Progenitor T-cell differentiation from hematopoietic stem cells using Delta-like-4 and VCAM-1 Nat. Methods, 2017-014(5):531-538.
PMID: 28394335
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A Itoh-Nakad et al. (2017-03-07), A Bach2-Cebp Gene Regulatory Network for the Commitment of Multipotent Hematopoietic Progenitors Cell Rep, 2017-018(10):2401-2414.
PMID: 28273455
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

B Guo et al. (2017-03-06), Glucocorticoid hormone-induced chromatin remodeling enhances human hematopoietic stem cell homing and engraftment Nat. Med, 2017-00(0).
PMID: 28263313
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

JL Weaver et al. (2017-02-14), Hematopoietic pannexin 1 function is critical for neuropathic pain Sci Rep, 2017-07(0):42550.
PMID: 28195232
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

AJ Garton et al. (2017-01-30), Anti-KIT Monoclonal Antibody Treatment Enhances the Anti-Tumor Activity of Immune Checkpoint Inhibitors by Reversing Tumor-Induced Immunosuppression Mol. Cancer Ther, 2017-00(0).
PMID: 28138031
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Y Han et al. (2017-01-30), Mesenchymal Cell Reprogramming in Experimental MPLW515L Mouse Model of Myelofibrosis PLoS ONE, 2017-012(1):e0166014.
PMID: 28135282
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

KZ Oben et al. (2017-01-12), Radiation Induced Apoptosis of Murine Bone Marrow Cells Is Independent of Early Growth Response 1 (EGR1) PLoS ONE, 2017-012(1):e0169767.
PMID: 28081176
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016-12-06), Inï¿½Vitro Derivation and Propagation of Spermatogonial Stem Cell Activity from Mouse Pluripotent Stem Cells Cell Rep, 2016-117(10):2789-2804.
PMID: 27926879
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016-12-05), Dickkopf-1 promotes hematopoietic regeneration via direct and niche-mediated mechanisms Nat. Med, 2016-10(0).
PMID: 27918563
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016-11-24), The non-canonical Wnt receptor Ryk regulates hematopoietic stem cell repopulation in part by controlling proliferation and apoptosis Cell Death Dis, 2016-17(11):e2479.
PMID: 27882948
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016-11-21), Pot1 OB-fold mutations unleash telomere instability to initiate tumorigenesis Oncogene, 2016-10(0).
PMID: 27869160
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016-11-21), Reprogramming mouse fibroblasts into engraftable myeloerythroid and lymphoid progenitors Nat Commun, 2016-17(0):13396.
PMID: 27869129
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016-09-14), Chronic myelogenous leukemia initiating cells require Polycomb group protein EZH2 Cancer Discov, 2016-00(0).
PMID: 27630126
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016-08-18), Arid3b Is Critical for B Lymphocyte Development PLoS ONE, 2016-011(8):e0161468.
PMID: 27537840
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016-08-03), Systemic Ablation of MMP9 Triggers Invasive Growth and Metastasis of Pancreatic Cancer via Deregulation of IL-6 Expression in the Bone Marrow Mol Cancer Res, 2016-00(0).
PMID: 27489361
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016-07-21), Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency Stem Cell Reports, 2016-00(0).
PMID: 27453007
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016-07-18), Reprogramming Mï¿½ller glia via in vivo cell fusion regenerates murine photoreceptors J Clin Invest, 2016-00(0).
PMID: 27427986
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Franziska Ruf (2016-06-30), Loss of Sfrp2 in the Niche Amplifies Stress-Induced Cellular Responses, and Impairs the in Vivo Regeneration of the Hematopoietic Stem Cell Pool Stem Cells, 2016-00(0).
PMID: 27299503
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016-05-09), Gene Therapy Induces Antigen-Specific Tolerance in Experimental Collagen-Induced Arthritis PLoS ONE, 2016-011(5):e0154630.
PMID: 27159398
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016-05-02), Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins Nat. Med., 2016-022(6):672-8.
PMID: 27135740
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

X Jiang et al. (2016-04-26), miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia Nat Commun, 2016-07(0):11452.
PMID: 27116251
Species: Chicken
Sample Types: Whole Cells
Applications: Bioassay

L Dimitrov et al. (2016-04-21), Germline Gene Editing in Chickens by Efficient CRISPR-Mediated Homologous Recombination in Primordial Germ Cells PLoS ONE, 2016-011(4):e0154303.
PMID: 27099923
Species: Chicken
Sample Types: Whole Cells
Applications: Bioassay

PA Leighton et al. (2016-03-31), Generation of chickens expressing Cre recombinase Transgenic Res, 2016-00(0).
PMID: 27034267
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

von Wnuck Lipinski K et al. (2016-01-22), Hepatocyte Nuclear Factor 1A Is a Cell-Intrinsic Transcription Factor Required for B Cell Differentiation and Development in Mice. J Immunol, 2016-0196(4):1655-65.
PMID: 26800876
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Gonzalez Roldan N et al. (2015-12-09), CD252 regulates mast cell mediated, CD1d-restricted NKT-cell activation in mice. Eur J Immunol, 2015-146(2):432-9.
PMID: 26564814
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

O Iijima et al. (2015-11-19), Prevention of Lethal Murine Hypophosphatasia by Neonatal Ex Vivo Gene Therapy Using Lentivirally Transduced Bone Marrow Cells Hum. Gene Ther, 2015-126(12):801-12.
PMID: 26467745
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Huan J et al. (2015-06-25), Coordinate regulation of residual bone marrow function by paracrine trafficking of AML exosomes. Leukemia, 2015-029(12):2285-95.
PMID: 26108689
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Liu D et al. (2015-06-22), Inhibition of Donor-Reactive CD8+ T Cell Responses by Selective CD28 Blockade Is Independent of Reduced ICOS Expression. PLoS ONE, 2015-010(6):e0130490.
PMID: 26098894
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Sato T et al. (2015-06-12), In Vitro Spermatogenesis in Explanted Adult Mouse Testis Tissues. PLoS ONE, 2015-010(6):e0130171.
PMID: 26065832
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Schumacher A et al. (2015-06-09), Angptl4 is upregulated under inflammatory conditions in the bone marrow of mice, expands myeloid progenitors, and accelerates reconstitution of platelets after myelosuppressive therapy. J Hematol Oncol, 2015-08(0):64.
PMID: 26054961
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Wang H et al. (2015-04-20), HoxA10 Terminates Emergency Granulopoiesis by Increasing Expression of Triad1. J Immunol, 2015-0194(11):5375-87.
PMID: 25895533
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Kim P et al. (2015-04-13), Flow-induced protein kinase A-CREB pathway acts via BMP signaling to promote HSC emergence. J Exp Med, 2015-0212(5):633-48.
PMID: 25870201
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Begonja A et al. (2015-04-02), FlnA binding to PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes and platelets. Blood, 2015-0126(1):80-8.
PMID: 25838348
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Suzuki et al. (2015-03-19), In vivo regulation of erythropoiesis by chemically inducible dimerization of the erythropoietin receptor intracellular domain. PLoS ONE, 2015-010(3):e0119442.
PMID: 25790231
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Miyawaki K et al. (2015-03-01), CD41 marks the initial myelo-erythroid lineage specification in adult mouse hematopoiesis: redefinition of murine common myeloid progenitor. Stem Cells, 2015-033(3):976-87.
PMID: 25446279
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Goldenson B et al. (2015-02-10), Aurora kinase A is required for hematopoiesis but is dispensable for murine megakaryocyte endomitosis and differentiation. Blood, 2015-0125(13):2141-50.
PMID: 25670627
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Wang L et al. (2015-02-06), The role of Lin28b in myeloid and mast cell differentiation and mast cell malignancy. Leukemia, 2015-029(6):1320-30.
PMID: 25655194
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Mayle A et al. (2015-01-22), Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation. Blood, 2015-0125(4):629-38.
PMID: 25416277
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Bando J et al. (2014-12-15), Identification and distribution of developing innate lymphoid cells in the fetal mouse intestine. Nat Immunol, 2014-116(2):153-60.
PMID: 25501629
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Bender M et al. (2014-12-02), Dynamin 2-dependent endocytosis is required for normal megakaryocyte development in mice. Blood, 2014-1125(6):1014-24.
PMID: 25468568
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Li B et al. (2014-10-20), Targeted 25-hydroxyvitamin D3 1alpha-hydroxylase adoptive gene therapy ameliorates dss-induced colitis without causing hypercalcemia in mice. Mol Ther, 2014-123(2):339-51.
PMID: 25327179
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Illert et al. (2014-09-24), Grb10 is involved in BCR-ABL-positive leukemia in mice. Leukemia, 2014-029(4):858-68.
PMID: 25249015
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Chen H et al. (2014-08-28), A novel molecule Me6TREN promotes angiogenesis via enhancing endothelial progenitor cell mobilization and recruitment. Sci Rep, 2014-04(0):6222.
PMID: 25164363
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Luyten A et al. (2014-08-15), Active enhancers are delineated de novo during hematopoiesis, with limited lineage fidelity among specified primary blood cells. Genes Dev, 2014-028(16):1827-39.
PMID: 25128499
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Liu X et al. (2014-08-13), The DNA binding property of PML/RARA but not the integrity of PML nuclear bodies is indispensable for leukemic transformation. PLoS ONE, 2014-09(8):e104906.
PMID: 25119106
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Boettcher S et al. (2014-07-02), Endothelial cells translate pathogen signals into G-CSF-driven emergency granulopoiesis. Blood, 2014-0124(9):1393-403.
PMID: 24990886
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Kim E et al. (2014-07-01), Embryonic stem cell-derived haematopoietic progenitor cells down-regulate the CD3 xi chain on T cells, abrogating alloreactive T cells. Immunology, 2014-0142(3):421-30.
PMID: 24527810
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Bettini M et al. (2014-06-18), TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential. J Immunol, 2014-0193(2):571-9.
PMID: 24943217
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Fukuda et al. (2014-06-06), Survivin modulates genes with divergent molecular functions and regulates proliferation of hematopoietic stem cells through Evi-1. Leukemia, 2014-029(2):433-40.
PMID: 24903482
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Patnode M et al. (2014-06-02), Leukotriene B4 amplifies eosinophil accumulation in response to nematodes. J Exp Med, 2014-0211(7):1281-8.
PMID: 24889202
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Nakahara F et al. (2014-05-13), Hes1 promotes blast crisis in chronic myelogenous leukemia through MMP-9 upregulation in leukemic cells. Blood, 2014-0123(25):3932-42.
PMID: 24825862
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Nagareddy P et al. (2014-05-06), Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity. Cell Metab, 2014-019(5):821-35.
PMID: 24807222
Species: Rabbit
Sample Types: Whole Cells
Applications: Bioassay

Nam T et al. (2014-04-23), Critical role for NAD glycohydrolase in regulation of erythropoiesis by hematopoietic stem cells through control of intracellular NAD content. J Biol Chem, 2014-0289(23):16362-73.
PMID: 24759100
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Park S et al. (2014-04-07), Computational promoter modeling identifies the modes of transcriptional regulation in hematopoietic stem cells. PLoS ONE, 2014-09(4):e93853.
PMID: 24710559
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Hiragun T et al. (2014-04-02), Establishment of a mast cell line, NCL-2, without Kit mutation, derived from NC mouse bone marrow. FEBS Open Bio, 2014-04(0):342-6.
PMID: 24918047
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Wallington-Beddoe C et al. (2014-03-31), Sphingosine kinase 2 promotes acute lymphoblastic leukemia by enhancing MYC expression. Cancer Res, 2014-074(10):2803-15.
PMID: 24686171
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Krutikov K et al. (2014-02-26), Ectopic TLX1 expression accelerates malignancies in mice deficient in DNA-PK. PLoS ONE, 2014-09(2):e89649.
PMID: 24586935
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Chung et al. (2014-02-14), Gene therapy delivery of myelin oligodendrocyte glycoprotein (MOG) via hematopoietic stem cell transfer induces MOG-specific B cell deletion. J Immunol, 2014-0192(6):2593-601.
PMID: 24532581
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Zimdahl et al. (2014-02-02), Lis1 regulates asymmetric division in hematopoietic stem cells and in leukemia. Nat Genet, 2014-046(3):245-52.
PMID: 24487275
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Reber L et al. (2014-01-22), Mast cells contribute to bleomycin-induced lung inflammation and injury in mice through a chymase/mast cell protease 4-dependent mechanism. J Immunol, 2014-0192(4):1847-54.
PMID: 24453258
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Roderick et al. (2014-01-06), c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells. Blood, 2014-0123(7):1040-50.
PMID: 24394663
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

North et al. (2014-01-05), Modulation of Ras signaling alters the toxicity of hydroquinone, a benzene metabolite and component of cigarette smoke. BMC Cancer, 2014-014(0):6.
PMID: 24386979
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Zhang H et al. (2014-01-01), Expression of podocalyxin separates the hematopoietic and vascular potentials of mouse embryonic stem cell-derived mesoderm. Stem Cells, 2014-032(1):191-203.
PMID: 24022884
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Yamamizu K et al. (2013-11-27), Identification of transcription factors for lineage-specific ESC differentiation. Stem Cell Reports, 2013-11(6):545-59.
PMID: 24371809
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Yang J et al. (2013-09-27), BMP4 is required for the initial expression of MITF in melanocyte precursor differentiation from embryonic stem cells. Exp Cell Res, 2013-0320(1):54-61.
PMID: 24080013
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Pereira C et al. (2013-06-13), Induction of a hemogenic program in mouse fibroblasts. Cell Stem Cell, 2013-013(2):205-18.
PMID: 23770078
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Sandig H et al. (2013-03-06), IL-33 causes selective mast cell tolerance to bacterial cell wall products by inducing IRAK1 degradation. Eur J Immunol, 2013-043(4):979-88.
PMID: 23404570
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Jeong H et al. (2012-12-03), The critical role of mast cell-derived hypoxia-inducible factor-1alpha in human and mice melanoma growth. Int J Cancer, 2012-1132(11):2492-501.
PMID: 23161568
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Kinzfogl J et al. (2011-05-31), Neurexophilin 1 suppresses the proliferation of hematopoietic progenitor cells. Blood, 2011-0118(3):565-75.
PMID: 21628410
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Cook BD et al. (2011-04-22), Smad1 signaling restricts hematopoietic potential after promoting hemangioblast commitment. Blood, 2011-0117(24):6489-97.
PMID: 21515822
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Artus J et al. (2010-09-08), A role for PDGF signaling in expansion of the extra-embryonic endoderm lineage of the mouse blastocyst. Development, 2010-0137(20):3361-72.
PMID: 20826533
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Izawa K et al. (2009-06-26), An activating and inhibitory signal from an inhibitory receptor LMIR3/CLM-1: LMIR3 augments lipopolysaccharide response through association with FcRgamma in mast cells. J. Immunol., 2009-0183(2):925-36.
PMID: 19561101
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Dolgachev VA et al. (2009-01-15), Role of stem cell factor and bone marrow-derived fibroblasts in airway remodeling. Am. J. Pathol., 2009-0174(2):390-400.
PMID: 19147822
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Kerenyi MA et al. (2008-08-11), Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1. Blood, 2008-0112(9):3878-88.
PMID: 18694996
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Zhang P et al. (2008-05-15), The lineage-c-Kit+Sca-1+ cell response to Escherichia coli bacteremia in Balb/c mice. Stem Cells, 2008-026(7):1778-86.
PMID: 18483422
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay

Huynh H et al. (2008-03-27), Insulin-like growth factor-binding protein 2 secreted by a tumorigenic cell line supports ex vivo expansion of mouse hematopoietic stem cells. Stem Cells, 2008-026(6):1628-35.
PMID: 18369099
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Milenkovic N et al. (2007-12-06), Nociceptive tuning by stem cell factor/c-Kit signaling. Neuron, 2007-156(5):893-906.
PMID: 18054864
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Yamaguchi Y et al. (2007-11-15), IL-17B and IL-17C are associated with TNF-alpha production and contribute to the exacerbation of inflammatory arthritis. J. Immunol., 2007-1179(10):7128-36.
PMID: 17982105
Species: Human, Mouse, Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Whole Cells
Applications: Bioassay

Rajesh</LastName><ForeNam D</Initial et al. (2007-02-01), Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells. Stem Cells, 2007-025(2):490-9.
PMID: 17284653
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Yuan W et al. (2006-09-28), Commonly dysregulated genes in murine APL cells. Blood, 2006-0109(3):961-70.
PMID: 17008535
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Schmidt-Ott KM et al. (2006-07-31), c-kit delineates a distinct domain of progenitors in the developing kidney. Dev. Biol., 2006-0299(1):238-49.
PMID: 16942767
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Young MR (2006-07-01), Cytokine-containing gelfoam implants at a postsurgical tumor excision site to stimulate local immune reactivity. Int. J. Cancer, 2006-0119(1):133-8.
PMID: 16450395
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Braun BS et al. (2006-05-23), Somatic activation of a conditional KrasG12D allele causes ineffective erythropoiesis in vivo. Blood, 2006-0108(6):2041-4.
PMID: 16720837
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Yilmaz OH et al. (2005-10-11), SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity. Blood, 2005-1107(3):924-30.
PMID: 16219798
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Hofmann MC et al. (2005-02-01), Immortalization of mouse germ line stem cells. Stem Cells, 2005-023(2):200-10.
PMID: 15671143
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Gyotoku E et al. (2001-11-01), The IL-6 family cytokines, interleukin-6, interleukin-11, oncostatin M, and leukemia inhibitory factor, enhance mast cell growth through fibroblast-dependent pathway in mice. Arch. Dermatol. Res., 2001-1293(10):508-14.
PMID: 11820727
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Gardner RV et al. (1998-01-01), Stem cell factor improves the repopulating ability of primitive hematopoietic stem cells after sublethal irradiation (and, to a lesser extent) after bone marrow transplantation in mice. Involvement of ?-defensin 130 (DEFB130) in the macrophage microbicidal mechanisms for killing Plasmodium falciparum, 1998-016(2):112-9.
PMID: 9554035

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