Recombinant Mouse Prss28 Protein, CF
R&D Systems, part of Bio-Techne | Catalog # 4808-SE
Key Product Details
- R&D Systems NS0-derived Recombinant Mouse Prss28 Protein (4808-SE)
- Quality control testing to verify active proteins with lot specific assays by in-house scientists
- All R&D Systems proteins are covered with a 100% guarantee
Source
NS0
Accession #
Structure / Form
Pro form
Conjugate
Unconjugated
Applications
Enzyme Activity
Product Specifications
Source
Mouse myeloma cell line, NS0-derived mouse PRSS28 protein
Ala19-Gln274, with a C-terminal 10-His tag
Accession # Q924N9
Ala19-Gln274, with a C-terminal 10-His tag
Accession # Q924N9
Purity
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Endotoxin Level
<1.0 EU per 1 μg of the protein by the LAL method.
N-terminal Sequence Analysis
Ala19
Predicted Molecular Mass
30 kDa
SDS-PAGE
34 kDa, reducing conditions
Activity
Measured by its ability to cleave a peptide substrate, Suc-VPF-SBzl after activation by Thermolysin.
The specific activity is >15,000 pmol/min/µg, as measured under the described conditions.
The specific activity is >15,000 pmol/min/µg, as measured under the described conditions.
Formulation, Preparation and Storage
4808-SE
| Formulation | Supplied as a 0.2 μm filtered solution in Tris and NaCl. |
| Shipping | The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
Background: PRSS28
Mouse Prss28, also known as Implantation Serine Protease 1 (ISP1), belongs to the S1 serine proteinase family with a conserved Histidine-Aspartic Acid-Serine catalytic triad (1). It closely resembles the mouse mast cell tryptases, specifically MCP-6 and MCP-7 (1). It is co-expressed with ISP2/Prss29 in pre-implantation embryos and uterus (2). It is involved with embryo hatching and its activity is important for successful implantation (2).
References
- Tang, L. and D. E. Rancourt (2005) Gene 364:30.
- Sharma, N. et al. (2006) BMC Developmental Biology 6:61.
Long Name
Protease, Serine, 28
Alternate Names
ISP1
Entrez Gene IDs
114661 (Mouse)
Gene Symbol
PRSS28
UniProt
Additional PRSS28 Products
Product Documents for Recombinant Mouse Prss28 Protein, CF
Product Specific Notices for Recombinant Mouse Prss28 Protein, CF
For research use only
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