Recombinant Mouse IGF-I/IGF-1 Protein, CF Best Seller

Name: Recombinant Mouse IGF-I/IGF-1 Protein, CF
Brand: R&D Systems
SKU: 791-MG

Catalog # 791-MG | R&D Systems, Inc. a Bio-Techne Brand

Citations (74)

Product Datasheet / COA / SDS

Setting the standard in quality research reagents

Key Product Details

Source:	E. coli
Accession #:	Q8CAR0
Applications:	Bioactivity

View Full Technical Details for Recombinant Mouse IGF-I/IGF-1 Protein, CF

Technical Data
Citations (74) / Reviews

Product Specifications for Recombinant Mouse IGF-I/IGF-1 Protein, CF

Source	E. coli-derived mouse IGF-I/IGF-1 protein Gly33-Ala102
Purity	>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin level	<0.10 EU per 1 μg of the protein by the LAL method.
N-terminal sequence Analysis	Gly33
Predicted Molecular Mass	7.6 kDa
SDS-PAGE	7.6 kDa
Activity	Measured in a serum-free cell proliferation assay using MCF‑7 human breast cancer cells. Karey, K.P. et al. (1988) Cancer Research 48:4083. The ED₅₀ for this effect is 0.4-2 ng/mL.

Scientific Data Examples for Recombinant Mouse IGF-I/IGF-1 Protein, CF

	Recombinant Mouse IGF-I/IGF-1 Protein Bioactivity Recombinant Mouse IGF-I/IGF-1 (Catalog # 791-MG) stimulates cell proliferation in a serum-free assay using the MCF-7 human breast cancer cell line. The ED₅₀ for this effect is 0.4-2 ng/mL.
	Recombinant Mouse IGF-I/IGF-1 Protein SDS-PAGE 1 µg/lane of Recombinant Mouse IGF-I/IGF-1 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 8 kDa.

Formulation, Preparation and Storage

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

791-MG

Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	Reconstitute at 100 μg/mL in sterile PBS. Reconstitution Buffer Available: Size / Price Qty Loading... RB01:
Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage:	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: IGF-I/IGF-1

Insulin-like growth factor I, also known as somatomedin C, is the dominant effector of growth hormone and is structurally homologous to proinsulin. Mouse IGF-I/IGF-1 is synthesized as two precursor isoforms with alternate N- and C-terminal propeptides (1). These isoforms are differentially expressed by various tissues (1). The 7.6 kDa mature IGF-I/IGF-1 is identical between isoforms and is generated by proteolytic removal of the N- and C-terminal regions. Mature mouse IGF-I/IGF-1 shares 94% and 99% aa sequence identity with human and rat IGF-I/IGF-1, respectively (2), and exhibits cross-species activity. It shares 60% aa sequence identity with mature mouse IGF-II/IGF-2. Circulating IGF-I/IGF-1 is produced by hepatocytes, while local IGF-I/IGF-1 is produced by many other tissues in which it has paracrine effects (1). IGF-I/IGF-1 induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally (3). IGF-I/IGF-1 regulates glucose and fatty acid metabolism, steroid hormone activity, and cartilage and bone metabolism (4-7). It plays an important role in muscle regeneration and tumor progression (1, 8). IGF-I/IGF-1 binds IGF-I R, IGF-II R, and the insulin receptor, although its effects are mediated primarily by IGF-I R (9). IGF-I/IGF-1 association with IGF binding proteins increases its plasma half-life and modulates its interactions with receptors (10).

Item	Value
References	Philippou, A. et al. (2007) In Vivo 21:45. Bell, G.I. et al. (1986) Nucleic Acids Res. 14:7873. Guvakova, M.A. (2007) Int. J. Biochem. Cell Biol. 39:890. Clemmons, D.R. (2006) Curr. Opin. Pharmacol. 6:620. Bluher, S. et al. (2005) Best Pract. Res. Clin. Endocrinol. Metab. 19:577. Garcia-Segura, L.M. et al. (2006) Neuroendocrinology 84:275. Malemud, C.J. (2007) Clin. Chim. Acta 375:10. Samani, A.A. et al. (2007) Endocrine Rev. 28:20. LeRoith, D. and S. Yakar (2007) Nat. Clin. Pract. Endocrinol. Metab. 3:302. Denley, A. et al. (2005) Cytokine Growth Factor Rev. 16:421.
Long Name	Insulin-like Growth Factor I/Insulin-like Growth Factor 1
Entrez Gene IDs	3479 (Human); 16000 (Mouse); 24482 (Rat)
Alternate Names	IBP1, IGF-1, IGF-I, IGF-IA, IGF-IB, IGF1, IGF1A, IGFI, MGF, Mechano growth factor, Somatomedin A, Somatomedin C, insulin-like growth factor 1, insulin-like growth factor 1 (somatomedin C), insulin-like growth factor I, insulin-like growth factor IA, insulin-like growth factor IB, somatomedin-C

Citations for Recombinant Mouse IGF-I/IGF-1 Protein, CF (74)

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Citations are publications that use Bio-Techne products. Selected citations for Recombinant Mouse IGF-I/IGF-1 Protein, CF include:

Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Andries et al. (2023-05-24), Immune stimulation recruits a subset of pro-regenerative macrophages to the retina that promotes axonal regrowth of injured neurons Acta neuropathologica communications
PMID: 37226256
Species: Mouse
Sample Types: Organoids
Applications: Cell Culture

Haensel et al. (2023-05-10), Skin basal cell carcinomas assemble a pro-tumorigenic spatially organized and self-propagating Trem2+ myeloid niche Nature communications
PMID: 37164949
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

KW Southerlan et al. (2023-04-03), Pro-inflammatory macrophages impair skeletal muscle regeneration in ischemic-damaged limbs by inducing precocious differentiation of satellite cells bioRxiv : the preprint server for biology, 2023-00(0).
PMID: 37066299
Species: Mouse
Sample Types: Organoid
Applications: Bioassay

X Hong et al. (2022-12-15), Kir4.1 channel activation in NG2 glia contributes to remyelination in ischemic stroke EBioMedicine, 2022-187(0):104406.
PMID: 36527899
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

R Lesage et al. (2022-11-09), An integrated in silico-in vitro approach for identifying therapeutic targets against osteoarthritis Bmc Biology, 2022-120(1):253.
PMID: 36352408
Species: Mouse
Sample Types: Organoids
Applications: Bioassay

A Hiroto et al. (2022-11-02), Stromal androgen signaling acts as tumor niches to drive prostatic basal epithelial progenitor-initiated oncogenesis Nature Communications, 2022-113(1):6552.
PMID: 36323713
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

L Wang et al. (2022-09-29), RNA-seq transcriptomic analysis of 4-octyl itaconate repressing myogenic differentiation Archives of biochemistry and biophysics, 2022-00(0):109420.
PMID: 36183843
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

MRF Gosselin et al. (2022-09-27), Loss of full-length dystrophin expression results in major cell-autonomous abnormalities in proliferating myoblasts Elife, 2022-011(0).
PMID: 36164827
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

ALM Caldwell et al. (2022-08-30), Aberrant astrocyte protein secretion contributes to altered neuronal development in multiple models of neurodevelopmental disorders Nature Neuroscience, 2022-025(9):1163-1178.
PMID: 36042312
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

SJ Cha et al. (2022-01-25), Identification of Key Determinants of Cerebral Malaria Development and Inhibition Pathways MBio, 2022-00(0):e0370821.
PMID: 35073748
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

R Deshycka et al. (2021-11-03), Engineered red blood cells carrying PCSK9 inhibitors persistently lower LDL and prevent obesity PLoS ONE, 2021-116(11):e0259353.
PMID: 34731223
Species: Transgenic Mouse
Sample Types: In Vivo
Applications: In Vivo

P Maity et al. (2021-08-31), Persistent JunB activation in fibroblasts disrupts stem cell niche interactions enforcing skin aging Cell Reports, 2021-036(9):109634.
PMID: 34469740
Species: Mouse
Sample Types: Recombinant Protein
Applications: Western Blot Control

HJ Kok et al. (2021-07-19), Muscle insulin-like growth factor-I modulates murine craniofacial bone growth European cells materials, 2021-07-19;41(0):72-89.
PMID: 34279041
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

M Mohrin et al. (2021-02-09), Inhibition of longevity regulator PAPP-A modulates tissue homeostasis via restraint of mesenchymal stromal cells Aging Cell, 2021-00(0):e13313.
PMID: 33561324
Species: Mouse
Sample Types: Organoid
Applications: Bioassay

M Kubota et al. (2021-01-19), Greater epithelial ridge cells are the principal organoid-forming progenitors of the mouse cochlea Cell Reports, 2021-034(3):108646.
PMID: 33472062
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

JB Conart et al. (2020-11-26), Insulin inhibits inflammation-induced cone death in retinal detachment J Neuroinflammation, 2020-117(1):358.
PMID: 33243251
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

J Xu et al. (2020-10-30), Embryonic stem cell-derived mesenchymal stem cells promote colon epithelial integrity and regeneration by elevating circulating IGF-1 in colitis mice Theranostics, 2020-110(26):12204-12222.
PMID: 33204338
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

T Hioki et al. (2020-08-30), Resveratrol suppresses insulin-like growth factor I-induced osteoblast migration: attenuation of the p44/p42 MAP kinase pathway Biosci. Biotechnol. Biochem., 2020-00(0):1-12.
PMID: 32862787
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

AL Gill et al. (2019-12-11), Primary Neurons and Differentiated NSC-34 Cells Are More Susceptible to Arginine-Rich ALS Dipeptide Repeat Protein-Associated Toxicity than Non-Differentiated NSC-34 and CHO Cells Int J Mol Sci, 2019-120(24).
PMID: 31835664
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

S Li et al. (2019-11-14), TSLP protects against liver I/R injury via activation of the PI3K/Akt pathway JCI Insight, 2019-14(22).
PMID: 31723054
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

T Abe et al. (2019-10-19), Food deprivation during active phase induces skeletal muscle atrophy via IGF-1 reduction in mice Arch. Biochem. Biophys., 2019-10(0):108160.
PMID: 31639326
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

MW Laschke et al. (2019-09-27), Insulin-like growth factor 1 stimulates the angiogenic activity of adipose tissue-derived microvascular fragments J Tissue Eng, 2019-010(0):2041731419879.
PMID: 31632630
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

SK Nandakumar et al. (2019-05-09), Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis Elife, 2019-08(0).
PMID: 31070582
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

I Meln et al. (2019-04-05), Dietary calories and lipids synergistically shape adipose tissue cellularity during postnatal growth Mol Metab, 2019-024(0):139-148.
PMID: 31003943
Species: Mouse
Sample Types: Biofilm
Applications: Bioassay

T Oyanagi et al. (2019-01-23), Insulin-like growth factor 1 modulates bioengineered tooth morphogenesis Sci Rep, 2019-09(1):368.
PMID: 30675004
Species: Mouse

L Qian et al. (2018-12-04), Reduced production of laminin by hepatic stellate cells contributes to impairment in oval cell response to liver injury in aged mice Aging (Albany NY), 2018-10(0).
PMID: 30513510
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

SY Lee et al. (2018-11-16), Glucose metabolism induced by Bmp signaling is essential for murine skeletal development Nat Commun, 2018-19(1):4831.
PMID: 30446646
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

LE Hillers et al. (2018-10-12), Obesity-Activated Adipose-Derived Stromal Cells Promote Breast Cancer Growth and Invasion Neoplasia, 2018-120(11):1161-1174.
PMID: 30317122
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

AM Lager et al. (2018-09-13), Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells Nat Commun, 2018-09(1):3708.
PMID: 30213958
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A Rasheed et al. (2018-05-08), Loss of the Liver X Receptors Disrupts the Balance of Hematopoietic Populations, With Detrimental Effects on Endothelial Progenitor Cells J Am Heart Assoc, 2018-07(10).
PMID: 29739800
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

L Decourtye et al. (2018-02-21), Impact of insulin on primary arcuate neurons culture is dependent on early-postnatal nutritional status and neuronal subpopulation PLoS ONE, 2018-013(2):e0193196.
PMID: 29466413
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

NJ Huang et al. (2017-09-04), Genetically engineered red cells expressing single domain camelid antibodies confer long-term protection against botulinum neurotoxin Nat Commun, 2017-08(1):423.
PMID: 28871080
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

R Cintron-Co et al. (2017-08-21), Insulin-like growth factor 1 receptor regulates hypothermia during calorie restriction Proc. Natl. Acad. Sci. U.S.A., 2017-00(0).
PMID: 28827363
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

T Iki et al. (2017-06-29), Microarray analyses of otospheres derived from the cochlea in the inner ear identify putative transcription factors that regulate the characteristics of otospheres PLoS ONE, 2017-012(6):e0179901.
PMID: 28662075
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

M Akiel et al. (2017-06-15), IGFBP7 Deletion Promotes Hepatocellular Carcinoma Cancer Res., 2017-00(0).
PMID: 28619711
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

R Garg et al. (2017-04-11), Protein Kinase C Epsilon Cooperates with PTEN Loss for Prostate Tumorigenesis through the CXCL13-CXCR5 Pathway Cell Rep, 2017-019(2):375-388.
PMID: 28402859
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

L Chen et al. (2017-03-15), Expression of antisense of microRNA-26a-5p in mesenchymal stem cells increases their therapeutic effects against cirrhosis Am J Transl Res, 2017-09(3):1500-1508.
PMID: 28386375
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

S Schaller et al. (2017-03-07), Novel combinatorial screening identifies neurotrophic factors for selective classes of motor neurons Proc. Natl. Acad. Sci. U.S.A, 2017-0114(12):E2486-E2493.
PMID: 28270618
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

G Valenti et al. (2017-02-15), Cancer stem cells regulate cancer-associated fibroblasts via activation of Hedgehog signaling in mammary gland tumors Cancer Res, 2017-00(0).
PMID: 28202523
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016-11-29), EZH1 and EZH2 promote skeletal growth by repressing inhibitors of chondrocyte proliferation and hypertrophy Nat Commun, 2016-17(0):13685.
PMID: 27897169
Species: Mouse
Sample Types: Whole Cells

Aiko Inoue (2016-11-29), Exercise restores muscle stem cell mobilization, regenerative capacity and muscle metabolic alterations via adiponectin/AdipoR1 activation in SAMP10 mice J Cachexia Sarcopenia Muscle, 2016-10(0).
PMID: 27897419
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

(2016-10-26), The Semaphorin 4D-RhoA-Akt Signal Cascade Regulates Enamel Matrix Secretion in Coordination with Cell Polarization During Ameloblast Differentiation J Bone Miner Res, 2016-10(0).
PMID: 27218883
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016-10-18), Bmi1 Loss in the Organ of Corti Results in p16ink4a Upregulation and Reduced Cell Proliferation of Otic Progenitors In Vitro PLoS ONE, 2016-111(10):e0164579.
PMID: 27755610
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

MC Fernandez et al. (2016-10-12), The type I insulin-like growth factor regulates the liver stromal response to metastatic colon carcinoma cells Oncotarget, 2016-18(32):52281-52293.
PMID: 28881729
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

L R Batista-Si (2016-06-10), Mycobacterium leprae-induced Insulin-like Growth Factor I attenuates antimicrobial mechanisms, promoting bacterial survival in macrophages Sci Rep, 2016-06(0):27632.
PMID: 27282338
Species: Mouse
Sample Types: Protein
Applications: Bioassay

Thor Tejada (2016-06-06), IGF-1 degradation by mouse mast cell protease 4 promotes cell death and adverse cardiac remodeling days after a myocardial infarction Proc Natl Acad Sci USA, 2016-00(0).
PMID: 27274047
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Bioassay

T Tando et al. (2016-04-15), Smad2/3 Proteins Are Required for Immobilization-induced Skeletal Muscle Atrophy J. Biol. Chem., 2016-0291(23):12184-94.
PMID: 27129272
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Esen E et al. (2015-07-14), PTH Promotes Bone Anabolism by Stimulating Aerobic Glycolysis via IGF Signaling. J Bone Miner Res, 2015-030(11):1959-68.
PMID: 25990470
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Barkho B et al. (2015-03-27), Proliferation of cultured mouse choroid plexus epithelial cells. PLoS ONE, 2015-010(3):e0121738.
PMID: 25815836
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Shaw A et al. (2015-01-28), TGFbeta signaling in myeloid cells regulates mammary carcinoma cell invasion through fibroblast interactions. PLoS ONE, 2015-010(1):e0117908.
PMID: 25629162
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Chen H et al. (2014-08-28), A novel molecule Me6TREN promotes angiogenesis via enhancing endothelial progenitor cell mobilization and recruitment. Sci Rep, 2014-04(0):6222.
PMID: 25164363
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Wang X et al. (2014-06-11), Intra-myocardial injection of both growth factors and heart derived Sca-1+/CD31- cells attenuates post-MI LV remodeling more than does cell transplantation alone: neither intervention enhances functionally significant cardiomyocyte regeneration. PLoS ONE, 2014-09(2):e95247.
PMID: 24919180
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Lou et al. (2014-05-29), Comparing the cultivated cochlear cells derived from neonatal and adult mouse. J Transl Med, 2014-012(0):150.
PMID: 24884939
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Harvey A et al. (2014-05-07), Calorie restriction decreases murine and human pancreatic tumor cell growth, nuclear factor-kappaB activation, and inflammation-related gene expression in an insulin-like growth factor-1-dependent manner. PLoS ONE, 2014-09(5):e94151.
PMID: 24804677
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Jiang X et al. (2014-04-09), HGF signaling impacts severity of Pseudomonas aeruginosa keratitis. Invest Ophthalmol Vis Sci, 2014-055(4):2180-90.
PMID: 24618323
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Wang Z et al. (2014-02-13), G(i)alpha proteins exhibit functional differences in the activation of ERK1/2, Akt and mTORC1 by growth factors in normal and breast cancer cells. Cell Commun Signal, 2014-012(0):10.
PMID: 24521094
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Rodgers B et al. (2014-01-01), Myostatin stimulates, not inihibits, C2C12 myoblast proliferation. Endocrinology, 2014-0155(3):670-5.
PMID: 24424069
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Wei W et al. (2013-11-26), Recombinant insulin-like growth factor-1 activates satellite cells in the mouse urethral rhabdosphincter. BMC Urol, 2013-113(0):62.
PMID: 24279352
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Wrann C et al. (2013-10-10), Exercise induces hippocampal BDNF through a PGC-1alpha/FNDC5 pathway. Cell Metab, 2013-118(5):649-59.
PMID: 24120943
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Yang J et al. (2013-09-27), BMP4 is required for the initial expression of MITF in melanocyte precursor differentiation from embryonic stem cells. Exp Cell Res, 2013-0320(1):54-61.
PMID: 24080013
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Osuka S et al. (2013-04-01), IGF1 receptor signaling regulates adaptive radioprotection in glioma stem cells. Stem Cells, 2013-031(4):627-40.
PMID: 23335250
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Guo T et al. (2013-01-10), Factors expressed by murine embryonic pancreatic mesenchyme enhance generation of insulin-producing cells from hESCs. Diabetes, 2013-062(5):1581-92.
PMID: 23305648
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Tucker B et al. (2012-12-27), Use of a synthetic xeno-free culture substrate for induced pluripotent stem cell induction and retinal differentiation. Stem Cells Transl Med, 2012-12(1):16-24.
PMID: 23283489
Species: Mouse
Sample Types: In Vivo
Applications: Bioassay

Takehara et al. (2012-11-19), The restorative effects of adipose-derived mesenchymal stem cells on damaged ovarian function. Lab Invest, 2012-193(2):181-93.
PMID: 23212100
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Zhao H et al. (2012-05-28), Age-Dependent Neuroimmune Modulation of IGF-1R in the Traumatic Mice. Immun Ageing, 2012-09(1):12.
PMID: 22640633
Sample Types: N/A
Applications: ELISA (Standard)

Mehta HH et al. (2011-06-22), IGFBP-3 is a metastasis suppression gene in prostate cancer. Cancer Res., 2011-071(15):5154-63.
PMID: 21697285
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Sanchez-Alavez M et al. (2011-02-17), Insulin-like Growth Factor 1-mediated Hyperthermia Involves Anterior Hypothalamic Insulin Receptors. J. Biol. Chem., 2011-0286(17):14983-90.
PMID: 21330367
Species: Rat
Sample Types: In Vivo
Applications: In Vivo

Chen DY et al. (2011-01-27), A critical role for IGF-II in memory consolidation and enhancement. Nature, 2011-0469(7331):491-7.
PMID: 21270887
Sample Types: N/A
Applications: ELISA (Standard)

Yamada PM et al. (2010-10-06), Evidence of a role for insulin-like growth factor binding protein (IGFBP)-3 in metabolic regulation. Endocrinology, 2010-1151(12):5741-50.
PMID: 20926583
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Hu J et al. (2009-08-18), Blockade of Wnt signaling inhibits angiogenesis and tumor growth in hepatocellular carcinoma. Cancer Res., 2009-069(17):6951-9.
PMID: 19690140
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Ostrovsky O et al. (2009-01-21), The chaperone activity of GRP94 toward insulin-like growth factor II is necessary for the stress response to serum deprivation. Mol. Biol. Cell, 2009-020(6):1855-64.
PMID: 19158397
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, In Vivo

Ashare A et al. (2008-04-24), Insulin-like growth factor-1 improves survival in sepsis via enhanced hepatic bacterial clearance. Am. J. Respir. Crit. Care Med., 2008-0178(2):149-57.
PMID: 18436791
Sample Types: N/A
Applications: ELISA (Standard)

Raina K et al. (2007-11-15), Dietary feeding of silibinin inhibits prostate tumor growth and progression in transgenic adenocarcinoma of the mouse prostate model. Cancer Res., 2007-167(22):11083-91.
PMID: 18006855
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Butovsky O et al. (2005-11-16), Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells. Mol. Cell. Neurosci., 2005-131(1):149-60.
PMID: 16297637

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