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Recombinant Mouse IFN-beta (Mammalian) Protein

Bio-Techne includes R&D Systems | Catalog # 12405-1

A New rm IFN-beta is Available! It has lower endotoxin specifications, is made in-house, and is priced competitively!
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12405-1

Key Product Details

Source

CHO

Accession #

Conjugate

Unconjugated

Applications

Bioactivity

Product Specifications

Predicted Molecular Mass

19.6 kDa

Formulation, Preparation and Storage

12405-1
Formulation

20 mM Sodium Phosphate, pH 6.4; 300 mM NaCl; 5% Glycerol; 0.1% bovine serum albumin (BSA)

Shipping The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage

After receipt, the product should be kept at -70°C or below for retention of full activity. Thaw product vial by incubation in cold tap water until just thawed - the contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum. Refreezing should be done on dry ice or in a dry ice/alcohol bath. Further dilution of the product should be in buffers containing protein such as 0.1% bovine serum albumin (BSA).

Background: IFN-beta

Interferon-beta (IFN-beta) is a cytokine that is produced by fibroblasts and pathogen-exposed dendritic cells, macrophages, and endothelial cells. It signals through the heterodimeric IFN-alpha/beta Receptor. IFN-beta-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis (EAE), a disease model of human multiple sclerosis (MS). Furthermore, IFN-beta has been shown to suppress the Th17 cell response in both MS and EAE and has commonly been used as a treatment for MS.

Long Name

Interferon beta

Alternate Names

IFB, IFF, IFNB, IFNB1, IFNbeta

Entrez Gene IDs

3456 (Human); 15977 (Mouse); 24481 (Rat)

Gene Symbol

IFNB1

UniProt

Additional IFN-beta Products

Product Documents for Recombinant Mouse IFN-beta (Mammalian) Protein

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Recombinant Mouse IFN-beta (Mammalian) Protein

For research use only