Does Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha Protein (Catalog # 350-NS or Catalog # 350-NS/CF) contain any tags?

Name: Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha
Brand: R&D Systems
SKU: 350-NS
Rating: 5 (4 reviews)

Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha Protein (Catalog # 350-NS or Catalog # 350-NS/CF) does not contain any tags. Please refer to the Source section on the product-specific page for sequence information.

Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha

R&D Systems, Inc. a Bio-Techne Brand

Catalog # 350-NS

Citations (169)

(4)

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Setting the standard in quality research reagents

Key Product Details

Source:	E. coli
Accession #:	P48061
Applications:	Bioactivity

View Full Technical Details for Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha

Product Specifications for Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha

Source	E. coli-derived CXCL12/SDF-1 alpha protein Lys22-Lys89
Purity	>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Endotoxin level	<0.01 EU per 1 μg of the protein by the LAL method.
N-terminal sequence Analysis	Lys22
Predicted Molecular Mass	8.0 kDa
SDS-PAGE	7 kDa, reducing conditions.
Activity	Measured by its ability to chemoattract 5-10 day cultured human peripheral blood lymphocytes (PBL). The ED₅₀ for this effect is 3‑9 ng/mL. Measured by its ability to chemoattract BaF3 mouse pro‑B cells transfected with human CXCR4. The ED₅₀ for this effect is 0.15‑0.6 ng/mL.

Scientific Data Examples for Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha

	Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha Bioactivity Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha (Catalog # 350-NS) chemoattracts the BaF3 mouse pro-B cells transfected with human CXCR4. The ED₅₀ for this effect is 0.15-0.6 ng/mL.
	Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha SDS-PAGE 1 μg/lane of Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 7 kDa.

Formulation, Preparation and Storage

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

350-NS

Carrier

Formulation	Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
Reconstitution	Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage:	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

350-NS/CF

Carrier Free

Formulation	Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA.
Reconstitution	Reconstitute at 100 μg/mL in sterile PBS.
Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage:	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

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The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: CXCL12/SDF-1 alpha

SDF-1 alpha and SDF-1 beta are the first cytokines initially identified using the signal sequence trap cloning strategy from a mouse bone-marrow stromal cell line. These proteins were subsequently also cloned from a human stromal cell line as cytokines that supported the proliferation of a stromal cell-dependent pre-B-cell line.
SDF-1 alpha and SDF-1 beta cDNAs encode precursor proteins of 89 and 93 amino acid residues, respectively. SDF-1 alpha and SDF-1 beta are encoded by a single gene and arise by alternative splicing. The two proteins are identical except for the four amino acid residues that are present in the carboxy-terminus of SDF-1 beta and absent from SDF-1 alpha. The amino acid sequence of SDF-1/PBSF identified the protein to be a member of the chemokine alpha subfamily that lacks the ELR domain. Unlike other known chemokine alpha and beta subfamily members that cluster on chromosomes 4 and 17, respectively, SDF-1/PBSF was mapped to chromosome 10q11.1. SDF-1/PBSF is highly conserved between species, with only one amino acid substitution between the mature human and mouse proteins. SDF-1/PBSF has been found to be a chemoattractant for T-lymphocytes and monocytes, but not neutrophils. SDF-1/PBSF was shown to be a ligand for CXCR4 (fusin/LESTR) receptor that functions as a co-receptor for lymphocyte-tropic HIV-1 strains. SDF-1/PBSF has been found to be a powerful inhibitor of infection by lymphocyte-tropic HIV-1 strains.

Item	Value
References	Tashiro, K. et al. (1993) Science 261:600. Bleul, C. et al. (1996) Nature 382:829. Oberlin, E. et al. (1996) Nature 382:833.
Entrez Gene IDs	6387 (Human); 20315 (Mouse); 493806 (Feline)
Alternate Names	CXCL12 chemokine (C-X-C motif) ligand 12, CXCL12/SDF-1 alpha, IRH, PBSF, SCYB12, SDF1, SDF1 alpha, SDF1B, SDF1a, TLSF, TPAR1

Citations for Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha (169)

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Citations are publications that use Bio-Techne products. Selected citations for Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha include:

Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

ML Capitano et al. (2022), DEK, a nuclear protein, is chemotactic for hematopoietic stem/progenitor cells acting through CXCR2 and Galphai signaling Journal of leukocyte biology, 0(0).
PMID: 35137444
Species: Human
Sample Types: Whole Cell
Applications: Bioassay

TA Burley et al. (2022), Elucidation of Focal Adhesion Kinase as a Modulator of Migration and Invasion and as a Potential Therapeutic Target in Chronic Lymphocytic Leukemia Cancers, 14(7).
PMID: 35406371
Species: Mouse
Sample Types: Bone Marrow Lavage Fluid
Applications: ELISA Control

C Fielding et al. (2022), Cholinergic signals preserve haematopoietic stem cell quiescence during regenerative haematopoiesis Nature Communications, 13(1):543.
PMID: 35087060
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Mastrogiov et al. (2022), The tumor suppressor adenomatous polyposis coli regulates T lymphocyte migration Science Advances, 8(15):eabl5942.
PMID: 35417240
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Xu et al. (2022), Discovery of Small Molecule Activators of Chemokine Receptor CXCR4 That Improve Diabetic Wound Healing International Journal of Molecular Sciences, 23(4).
PMID: 35216311
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Leng et al. (2022), Inflammation down regulates stromal cell-derived factor 1alpha in the early phase of pulpitis Cytokine, 158(0):155983.
PMID: 35930964
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Tobiume et al. (2022), Analysis of the chemotactic factors for tumor-infiltrating fibrocytes and their prognostic significances in lung cancer Oncology Letters, 24(5):417.
PMID: 36245829
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

X Yuan et al. (2022), SDF?1alpha/CXCR4 signaling promotes capillary tube formation of human retinal vascular endothelial cells by activating ERK1/2 and PI3K pathways inï¿½vitro Molecular Medicine Reports, 26(4).
PMID: 35946444
Species: Rat
Sample Types: Whole Tissue
Applications: Bioassay

K Bassand et al. (2021), miR-126-3p is essential for CXCL12-induced angiogenesis Journal of Cellular and Molecular Medicine, 0(0).
PMID: 34117709
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Yuzuriha et al. (2021), Extracellular laminin regulates hematopoietic potential of pluripotent stem cells through integrin &beta1-ILK-&beta-catenin-JUN axis Stem Cell Research, 53(0):102287.
PMID: 33813173
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Berrazouan et al. (2021), VLA-4 Induces Chemoresistance of T Cell Acute Lymphoblastic Leukemia Cells via PYK2-Mediated Drug Efflux Cancers, 13(14).
PMID: 34298726
Species: Mouse
Sample Types: Organoid
Applications: Bioassay

LA Ridge et al. (2021), Dual role for CXCL12 signaling in semilunar valve development Cell Reports, 36(8):109610.
PMID: 34433040
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

T Radaszkiew et al. (2021), RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy Elife, 10(0).
PMID: 34702444
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

W Feng et al. (2021), CXCL12-mediated HOXB5 overexpression facilitates Colorectal Cancer metastasis through transactivating CXCR4 and ITGB3 Theranostics, 11(6):2612-2633.
PMID: 33456563
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JY Kim et al. (2021), CXCR4 uses STAT3-mediated slug expression to maintain radioresistance of non-small cell lung cancer cells: emerges as a potential prognostic biomarker for lung cancer Cell Death Disease, 2021;12(1):48.
PMID: 33414415
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Y Fu et al. (2021), CD27-CD38+ B cells accumulated in early HIV infection exhibit transitional profile and promote HIV disease progression Cell Reports, 36(2):109344.
PMID: 34260905
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

H Levy-Baraz et al. (2020), Brief ex vivo Fas-ligand incubation attenuates GvHD without compromising stem cell graft performance Bone Marrow Transplant., 0(0).
PMID: 32433499
Species: Human

Applications: Functional Assay

L Chen et al. (2020), CXCR4 upregulation is an indicator of sensitivity to B-cell receptor/PI3K blockade and a potential resistance mechanism in B-cell receptor-dependent diffuse large B-cell lymphomas Haematologica, 105(5):1361-1368.
PMID: 31471373
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Y Wang et al. (2020), LRCH1 suppresses migration of CD4+ T cells and refers to disease activity in ulcerative colitis Int J Med Sci, 17(5):599-608.
PMID: 32210709
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

AA Chimote et al. (2020), A Compartmentalized Reduction in Membrane-Proximal Calmodulin Reduces the Immune Surveillance Capabilities of CD8+ T Cells in Head and Neck Cancer Front Pharmacol, 11(0):143.
PMID: 32184726
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

H Cho et al. (2020), iPSC-derived endothelial cell response to hypoxia via SDF1a/CXCR4 axis facilitates incorporation to revascularize ischemic retina JCI Insight, 5(6).
PMID: 32213707
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

D Biasci et al. (2020), CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response Proc Natl Acad Sci U S A, 0(0).
PMID: 33127761
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Fumagalli et al. (2020), The atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication Nat Commun, 11(1):4855.
PMID: 32978390
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

PR Norden et al. (2020), Control of endothelial tubulogenesis by Rab and Ral GTPases, and apical targeting of caveolin-1-labeled vacuoles PLoS ONE, 15(6):e0235116.
PMID: 32569321
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Lim et al. (2020), Glutathione dynamics determine the therapeutic efficacy of mesenchymal stem cells for graft-versus-host disease via CREB1-NRF2 pathway Sci Adv, 6(16):eaba1334.
PMID: 32490200
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

H Iseoka et al. (2020), Role and therapeutic effects of skeletal muscle-derived non-myogenic cells in a rat myocardial infarction model Stem Cell Res Ther, 11(1):69.
PMID: 32070429
Species: Human
Sample Types: Protein
Applications: Bioassay

J O'Dwyer et al. (2020), Development of a Sustained Release Nano-In-Gel Delivery System for the Chemotactic and Angiogenic Growth Factor Stromal-Derived Factor 1alpha Pharmaceutics, 12(6).
PMID: 32512712
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MJ Costa et al. (2019), Optimal design, anti-tumour efficacy and tolerability of anti-CXCR4 antibody drug conjugates Sci Rep, 9(1):2443.
PMID: 30792442
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Li et al. (2019), Activation of MAPK signaling by CXCR7 leads to enzalutamide resistance in prostate cancer Cancer Res., 0(0).
PMID: 30952632
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

W Liu et al. (2019), RhoGDI2 positively regulates the Rho GTPases activation in response to the ?2 outside-in signaling in T cells adhesion and migration on ICAM-1 J. Leukoc. Biol., 0(0).
PMID: 31075185
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

ML Capitano et al. (2019), Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signaling J. Clin. Invest., 130(0):2555-2570.
PMID: 31107242
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

C Ieranò et al. (2019), CXCL12 loaded-dermal filler captures CXCR4 expressing melanoma circulating tumor cells Cell Death Dis, 10(8):562.
PMID: 31332163
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Yang et al. (2019), TCF12 promotes the tumorigenesis and metastasis of hepatocellular carcinoma via upregulation of CXCR4 expression Theranostics, 9(20):5810-5827.
PMID: 31534521
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

NM Belle et al. (2019), TFF3 interacts with LINGO2 to regulate EGFR activation for protection against colitis and gastrointestinal helminths Nat Commun, 10(1):4408.
PMID: 31562318
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

F Caccuri et al. (2019), The Synthetic Dipeptide Pidotimod Shows a Chemokine-Like Activity through CXC Chemokine Receptor 3 (CXCR3) Int J Mol Sci, 20(21).
PMID: 31653015
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

LA Callender et al. (2019), Mitochondrial mass governs the extent of human T cell senescence Aging Cell, 0(0):e13067.
PMID: 31788930
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

PD Fromm et al. (2019), Distinguishing human peripheral blood CD16+ myeloid cells based on phenotypic characteristics J. Leukoc. Biol., 0(0).
PMID: 31749181
Species: Human
Sample Types: Recombinant Protein
Applications: Positive Control

DJ Wessels et al. (2019), Reciprocal signaling and direct physical interactions between fibroblasts and breast cancer cells in a 3D environment PLoS ONE, 14(6):e0218854.
PMID: 31233557
Sample Types: Whole Cells
Applications: Bioassay

F Jahan et al. (2018), Phosphorylation of the ?-chain in the integrin LFA-1 enables ?2-chain phosphorylation and ?-actinin binding required for cell adhesion J. Biol. Chem., 0(0).
PMID: 29903913
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

TI Moore et al. (2018), Measuring Integrin Conformational Change on the Cell Surface with Super-Resolution Microscopy Cell Rep, 22(7):1903-1912.
PMID: 29444440
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

W Tang et al. (2018), Interleukin-25 and eosinophils progenitor cell mobilization in allergic asthma Clin Transl Allergy, 8(0):5.
PMID: 29456832
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JJ Gell et al. (2018), PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation Stem Cell Res, 27(0):46-56.
PMID: 29324254
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Patalano et al. (2018), CXCL12/CXCR4-Mediated Procollagen Secretion Is Coupled To Cullin-RING Ubiquitin Ligase Activation Sci Rep, 8(1):3499.
PMID: 29472636
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Y Nam et al. (2018), Intraperitoneal infusion of mesenchymal stem cell attenuates severity of collagen antibody induced arthritis PLoS ONE, 13(6):e0198740.
PMID: 29879214
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

KM Dvorak et al. (2018), Carcinoma associated fibroblasts (CAFs) promote breast cancer motility by suppressing mammalian Diaphanous-related formin-2 (mDia2) PLoS ONE, 13(3):e0195278.
PMID: 29596520
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

T Ohta et al. (2018), Simple Physical Model Unravels Influences of Chemokine on Shape Deformation and Migration of Human Hematopoietic Stem Cells Sci Rep, 8(1):10630.
PMID: 30006633
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

E Vågesjö et al. (2018), Accelerated wound healing in mice by on-site production and delivery of CXCL12 by transformed lactic acid bacteria Proc. Natl. Acad. Sci. U.S.A., 0(0).
PMID: 29432190
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SYN Jamaludin et al. (2018), Assessment of CXC ligand 12-mediated calcium signalling and its regulators in basal-like breast cancer cells Oncol Lett, 15(4):4289-4295.
PMID: 29541196
BL Benson et al. (2018), Biomimetic post-capillary venule expansions for leukocyte adhesion studies Sci Rep, 8(1):9328.
PMID: 29921896
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

W He et al. (2018), Targeting CXC motif chemokine receptor 4 inhibits the proliferation, migration and angiogenesis of lung cancer cells Oncol Lett, 16(3):3976-3982.
PMID: 30128017
Species: Human
Sample Types: Whole Cells

S Mamand et al. (2018), Comparison of interleukin-2-inducible kinase (ITK) inhibitors and potential for combination therapies for T-cell lymphoma Sci Rep, 8(1):14216.
PMID: 30242208
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Y Bao et al. (2018), A feed-forward loop between nuclear translocation of CXCR4 and HIF-1? promotes renal cell carcinoma metastasis Oncogene, 0(0).
PMID: 30177838
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

LF Pavon et al. (2018), Tropism of mesenchymal stem cell toward CD133+ stem cell of glioblastoma in vitro and promote tumor proliferation in vivo Stem Cell Res Ther, 9(1):310.
PMID: 30413179
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JE Yoon et al. (2018), Senescent fibroblasts drive ageing pigmentation: ?A potential therapeutic target for senile lentigo Theranostics, 8(17):4620-4632.
PMID: 30279727
Species: Feline
Sample Types: Whole Cells
Applications: Bioassay

JL Rojo et al. (2018), Stromal-derived factor 1 directly promotes genes expressed within the ovulatory cascade in feline cumulus oocyte complexes J. Assist. Reprod. Genet., 0(0).
PMID: 29516335
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

H Sun et al. (2018), Transmission of integrin ?7 transmembrane domain topology enables gut lymphoid tissue development J. Cell Biol., 0(0).
PMID: 29535192
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Giarra et al. (2018), Engineering of thermoresponsive gels as a fake metastatic niche Carbohydr Polym, 191(0):112-118.
PMID: 29661298
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

H Plešingero et al. (2017), Expression of COBLL1 encoding novel ROR1 binding partner is robust predictor of survival in chronic lymphocytic leukemia Haematologica, 0(0).
PMID: 29122990
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

XJ Li et al. (2017), Mechanisms of CXCR7 induction in malignant melanoma development Oncol Lett, 14(4):4106-4114.
PMID: 28943917
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Veenstra et al. (2017), Frontline Science: CXCR7 mediates CD14(+)CD16(+) monocyte transmigration across the blood brain barrier: a potential therapeutic target for NeuroAIDS J. Leukoc. Biol., 0(0).
PMID: 28754798
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

PJ Stewart-Hu et al. (2017), Technical Advance: New in vitro method for assaying the migration of primary B cells using an endothelial monolayer as substrate J. Leukoc. Biol., 0(0).
PMID: 28637896
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

E Crompot et al. (2017), Extracellular vesicles of bone marrow stromal cells rescue chronic lymphocytic leukemia B-cells from apoptosis, enhance their migration and induce gene expression modifications Haematologica, 0(0).
PMID: 28596280
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

W Chen et al. (2017), Directional delivery of RSPO1 by mesenchymal stem cells ameliorates radiation-induced intestinal injury Cytokine, 95(0):27-34.
PMID: 28214675
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

H Al Faruque et al. (2017), Stepwise inhibition of T cell recruitment at post-capillary venules by orally active desulfated heparins in inflammatory arthritis PLoS ONE, 12(4):e0176110.
PMID: 28419144
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

X Liu et al. (2017), Endothelial progenitor cell dysfunction in acute exacerbation of chronic obstructive pulmonary disease Mol Med Rep, 0(0).
PMID: 28849108
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Zhang et al. (2017), CXCL12 enhances angiogenesis through CXCR7 activation in human umbilical vein endothelial cells Sci Rep, 7(1):8289.
PMID: 28811579
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JH Kim et al. (2017), Downregulation of UHRF1 increases tumor malignancy by activating the CXCR4/AKT-JNK/IL-6/Snail signaling axis in hepatocellular carcinoma cells Sci Rep, 7(1):2798.
PMID: 28584306
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Park et al. (2017), Directional migration of mesenchymal stem cells under an SDF-1? gradient on a microfluidic device PLoS ONE, 12(9):e0184595.
PMID: 28886159
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Müller et al. (2017), Designed cell consortia as fragrance-programmable analog-to-digital converters Nat. Chem. Biol, 0(0).
PMID: 28092361
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2017), MicroRNA expression profiles and networks in CXCL12?stimulated human endometrial stromal cells Mol Med Rep, 15(1):249-255.
PMID: 27959395
Species: Human
Sample Types: Antibody
Applications: Enzyme Assay

DI Bromage et al. (2017), A novel recombinant antibody specific to full-length stromal derived factor-1 for potential application in biomarker studies PLoS ONE, 12(4):e0174447.
PMID: 28379992
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

D Kobayashi et al. (2017), Regulation of CCR7-dependent cell migration throughï¿½CCR7 homodimer formation Sci Rep, 7(1):8536.
PMID: 28819198
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Z Jiang et al. (2017), Protein profiling identified key chemokines that regulate the maintenance of human pluripotent stem cells Sci Rep, 7(1):14510.
PMID: 29109449
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

C Wang et al. (2017), Hepatitis B virus X protein promotes the stem-like properties of OV6(+) cancer cells in hepatocellular carcinoma Cell Death Dis, 8(1):e2560.
PMID: 28102846
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Xu et al. (2017), Vascular CXCR4 expression promotes vessel sprouting and sensitivity to sorafenib treatment in hepatocellular carcinoma Clin. Cancer Res, 0(0).
PMID: 28223275
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Strazza et al. (2017), PLC?1 regulates SDF-1?-induced lymphocyte adhesion and migration to sites of inflammation Proc. Natl. Acad. Sci. U.S.A, 0(0).
PMID: 28213494
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

W Oliva-Oliv et al. (2017), Different response to hypoxia of adipose-derived multipotent cells from obese subjects with and without metabolic syndrome PLoS ONE, 12(11):e0188324.
PMID: 29166648
Species: Human
Sample Types: Recombinant Protein
Applications: Bioassay

R Desplantes et al. (2017), Affinity biosensors using recombinant native membrane proteins displayed on exosomes: application to botulinum neurotoxin B receptor Sci Rep, 7(1):1032.
PMID: 28432329
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Drouillard et al. (2017), Human Naive and Memory T Cells Display Opposite Migratory Responses to Sphingosine-1 Phosphate J. Immunol., 0(0).
PMID: 29237776
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Moslem et al. (2017), Kindlin-2 Modulates the Survival, Differentiation, and Migration of Induced Pluripotent Cell-Derived Mesenchymal Stromal Cells Stem Cells Int, 2017(0):7316354.
PMID: 28163724
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MT Logun et al. (2016), Glioma Cell Invasion is Significantly Enhanced in Composite Hydrogel Matrices Composed of Chondroitin 4- and 4,6-Sulfated Glycosaminoglycans J Mater Chem B Mater Biol Med, 4(36):6052-6064.
PMID: 28217304
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Patricia Freund (2016), Cannabinoid Receptors Are Overexpressed in CLL but of Limited Potential for Therapeutic Exploitation PLoS ONE, 11(6):e0156693.
PMID: 27248492
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016), Macrophage Migration Inhibitory Factor-CXCR4 Receptor Interactions: Evidence for Partial Allosteric Agonism in Comparison to CXCL12 J Biol Chem, 0(0).
PMID: 27226569
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016), HEREGULIN/ErbB3 SIGNALING ENHANCES CXCR4-DRIVEN Rac1 ACTIVATION AND BREAST CANCER CELL MOTILITY VIA HIF-1? Mol Cell Biol, 0(0).
PMID: 27185877
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016), SDF-1?-induced dual pairs of E-selectin/ligand mediate endothelial progenitor cell homing to critical ischemia Sci Rep, 6(0):34416.
PMID: 27713493
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Velasquez et al. (2016), Pannexin1 Channels Are Required for Chemokine-Mediated Migration of CD4+ T Lymphocytes: Role in Inflammation and Experimental Autoimmune Encephalomyelitis J Immunol, 0(0).
PMID: 27076682
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Xudong Shi (2016), Local CXCR4 Up-regulation in Injured Arterial Wall Contributes to Intimal Hyperplasia Stem Cells, 0(0).
PMID: 27340942
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Renren Bai (2016), Development of CXCR4 modulators by virtual HTS of a novel amide-sulfamide compound library Eur J Med Chem, 126(0):464-475.
PMID: 27914361
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Amber N Stratman (2016), Mural-Endothelial cell-cell interactions stabilize the developing zebrafish dorsal aorta Development, 0(0).
PMID: 27913637
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Janovska P et al. (2016), Autocrine Signaling by Wnt-5a Deregulates Chemotaxis of Leukemic Cells and Predicts Clinical Outcome in Chronic Lymphocytic Leukemia. Clin Cancer Res, 22(2):459-69.
PMID: 26240275
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Heinzmann D et al. (2015), The Novel Extracellular Cyclophilin A (CyPA) - Inhibitor MM284 Reduces Myocardial Inflammation and Remodeling in a Mouse Model of Troponin I -Induced Myocarditis. PLoS ONE, 10(4):e0124606.
PMID: 25894208
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Ray P et al. (2015), CXCL12-gamma in primary tumors drives breast cancer metastasis. Oncogene, 34(16):2043-51.
PMID: 24909174
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Williams D et al. (2015), JAM-A and ALCAM are therapeutic targets to inhibit diapedesis across the BBB of CD14+CD16+ monocytes in HIV-infected individuals. J Leukoc Biol, 97(2):401-12.
PMID: 25420915
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Walsh T et al. (2015), SDF-1alpha is a novel autocrine activator of platelets operating through its receptor CXCR4. Cell Signal, 27(1):37-46.
PMID: 25283599
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Chang T et al. (2015), Bortezomib inhibits expression of TGF-beta1, IL-10, and CXCR4, resulting in decreased survival and migration of cutaneous T cell lymphoma cells. J Immunol, 194(6):2942-53.
PMID: 25681335
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Ilkow C et al. (2015), Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity. Nat Med, 21(5):530-6.
PMID: 25894825
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Boudot A et al. (2014), COUP-TFI modifies CXCL12 and CXCR4 expression by activating EGF signaling and stimulates breast cancer cell migration. BMC Cancer, 14(0):407.
PMID: 24906407
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Vermi W et al. (2014), slanDCs selectively accumulate in carcinoma-draining lymph nodes and marginate metastatic cells. Nat Commun, 5(0):3029.
PMID: 24398631
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Zucco L et al. (2014), Circulating angiogenic cell dysfunction in patients with hereditary hemorrhagic telangiectasia. PLoS ONE, 9(2):e89927.
PMID: 24587130
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Westerweel et al. (2014), Impaired endothelial progenitor cell mobilization and dysfunctional bone marrow stroma in diabetes mellitus. PLoS ONE, 8(3):e60357.
PMID: 23555959
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Richter R et al. (2014), Identification and characterization of circulating variants of CXCL12 from human plasma: effects on chemotaxis and mobilization of hematopoietic stem and progenitor cells. Stem Cells Dev, 23(16):1959-74.
PMID: 24708339
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Ruiz E et al. (2014), A paracrine network regulates the cross-talk between human lung stem cells and the stroma. Nat Commun, 5(0):3175.
PMID: 24430801
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Ugarte-Berzal E et al. (2014), A novel CD44-binding peptide from the pro-matrix metalloproteinase-9 hemopexin domain impairs adhesion and migration of chronic lymphocytic leukemia (CLL) cells. J Biol Chem, 289(22):15340-9.
PMID: 24739387
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Krook M et al. (2014), Stress-induced CXCR4 promotes migration and invasion of ewing sarcoma. Mol Cancer Res, 12(6):953-64.
PMID: 24651452
Species: N/A
Sample Types: Chip
Applications: Bioassay

Hoellenriegel J et al. (2014), The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization. Blood, 123(7):1032-9.
PMID: 24277076
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Gharaee-Kermani M et al. (2014), Complex cellular composition of solitary fibrous tumor of the prostate. Am J Pathol, 184(3):732-9.
PMID: 24434011
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Butschkau et al. (2014), Protein z exerts pro-angiogenic effects and upregulates CXCR4. PLoS ONE, 9(12):e113554.
PMID: 25474349
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Coggins N et al. (2014), CXCR7 controls competition for recruitment of beta-arrestin 2 in cells expressing both CXCR4 and CXCR7. PLoS ONE, 9(6):e98328.
PMID: 24896823
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Lessey-Morillon E et al. (2014), The RhoA guanine nucleotide exchange factor, LARG, mediates ICAM-1-dependent mechanotransduction in endothelial cells to stimulate transendothelial migration. J Immunol, 192(7):3390-8.
PMID: 24585879
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Lo H et al. (2014), TNF-alpha induces CXCL1 chemokine expression and release in human vascular endothelial cells in vitro via two distinct signaling pathways. Acta Pharmacol Sin, 35(3):339-50.
PMID: 24487964
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Chigaev A et al. (2014), Carbon monoxide down-regulates alpha4beta1 integrin-specific ligand binding and cell adhesion: a possible mechanism for cell mobilization. BMC Immunol, 15(0):52.
PMID: 25367365
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Watson H et al. (2014), Heparan sulfate inhibits hematopoietic stem and progenitor cell migration and engraftment in mucopolysaccharidosis I. J Biol Chem, 289(52):36194-203.
PMID: 25359774
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cheng et al. (2013), Distinct angiogenesis roles and surface markers of early and late endothelial progenitor cells revealed by functional group analyses. BMC Genomics, 14(0):182.
PMID: 23496821
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Akimoto et al. (2013), Umbilical cord blood-derived mesenchymal stem cells inhibit, but adipose tissue-derived mesenchymal stem cells promote, glioblastoma multiforme proliferation. Stem Cells Dev, 22(9):1370-86.
PMID: 23231075
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Rossi E et al. (2013), Endothelial endoglin is involved in inflammation: role in leukocyte adhesion and transmigration. Blood, 121(2):403-15.
PMID: 23074273
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Wen W et al. (2013), Oligomannurarate sulfate inhibits CXCL12/SDF-1-mediated proliferation and invasion of human tumor cells in vitro. Acta Pharmacol Sin, 34(12):1554-9.
PMID: 24141568
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Smith A et al. (2013), Hematopoietic stem cell cytokines and fibroblast growth factor-2 stimulate human endothelial cell-pericyte tube co-assembly in 3D fibrin matrices under serum-free defined conditions. PLoS ONE, 8(12):e85147.
PMID: 24391990
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Hoque et al. (2013), PCaAnalyser: a 2D-image analysis based module for effective determination of prostate cancer progression in 3D culture. PLoS ONE, 8(11):e79865.
PMID: 24278197
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tai Y et al. (2012), Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma. Blood, 120(9):1877-87.
PMID: 22689860
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2012), Targeting of CD34+CD38- cells using Gemtuzumab ozogamicin (Mylotarg) in combination with tipifarnib (Zarnestra) in Acute Myeloid Leukaemia. BMC Cancer, 12(0):431.
PMID: 23013471
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Wilson TR et al. (2012), Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature, 487(7408):505-9.
PMID: 22763448
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Badr G et al. (2011), Thymoquinone inhibits the CXCL12-induced chemotaxis of multiple myeloma cells and increases their susceptibility to Fas-mediated apoptosis. PLoS ONE, 6(9):e23741.
PMID: 21912642
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Fujita-Sato S et al. (2011), Structural basis of digoxin that antagonizes RORgamma t receptor activity and suppresses Th17 cell differentiation and interleukin (IL)-17 production. J. Biol. Chem., 286(36):31409-17.
PMID: 21733845
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Yasumoto K et al. (2011), The EGFR ligands amphiregulin and heparin-binding egf-like growth factor promote peritoneal carcinomatosis in CXCR4-expressing gastric cancer. Clin. Cancer Res., 17(11):3619-30.
PMID: 21482691
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Burton VJ et al. (2011), Delay of migrating leukocytes by the basement membrane deposited by endothelial cells in long-term culture. Exp. Cell Res., 317(3):276-92.
PMID: 21056557
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Fujio M et al. (2011), Stromal cell-derived factor-1 enhances distraction osteogenesis-mediated skeletal tissue regeneration through the recruitment of endothelial precursors. Bone, 49(4):693-700.
PMID: 21741502
Species: Rat
Sample Types: In Vivo
Applications: In Vivo

Benamar K et al. (2011), Analgesic efficacy of buprenorphine in the presence of high levels of SDF-1alpha/CXCL12 in the brain. Drug Alcohol Depend, 114(2):246-8.
PMID: 21112161
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Charles J et al. (2010), Characterization of circulating dendritic cells in melanoma: role of CCR6 in plasmacytoid dendritic cell recruitment to the tumor. J. Invest. Dermatol., 130(6):1646-56.
PMID: 20220766
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Hachehouche LN et al. (2010), Implication of discoidin domain receptor 1 in T cell migration in three-dimensional collagen. Mol. Immunol., 47(9):1866-9.
PMID: 20353877
Species: Human
Sample Types: Whole Cells
Applications: Binding Assay

Berahovich RD et al. (2010), CXCR7 protein is not expressed on human or mouse leukocytes. J. Immunol., 185(9):5130-9.
PMID: 20889540
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Kenig S et al. (2010), Glioblastoma and endothelial cells cross-talk, mediated by SDF-1, enhances tumour invasion and endothelial proliferation by increasing expression of cathepsins B, S, and MMP-9. Cancer Lett., 289(1):53-61.
PMID: 19700239
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Sengupta N et al. (2010), Paracrine modulation of CXCR4 by IGF-1 and VEGF: implications for choroidal neovascularization. Invest. Ophthalmol. Vis. Sci., 51(5):2697-704.
PMID: 20007826
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Boniface K et al. (2009), Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling. J. Exp. Med., 206(3):535-48.
PMID: 19273625
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Crawford Y et al. (2009), PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment. Cancer Cell, 15(1):21-34.
PMID: 19111878
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Stratman AN et al. (2009), Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation. Blood, 114(24):5091-101.
PMID: 19822899
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Skrzeczynska-Moncznik J et al. (2009), Potential role of chemerin in recruitment of plasmacytoid dendritic cells to diseased skin. Biochem. Biophys. Res. Commun., 380(2):323-7.
PMID: 19168032
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Struyf S et al. (2009), Citrullination of CXCL12 differentially reduces CXCR4 and CXCR7 binding with loss of inflammatory and anti-HIV-1 activity via CXCR4. J. Immunol., 182(1):666-74.
PMID: 19109200
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Zhu Y et al. (2009), CXCR3 activation by lentivirus infection suppresses neuronal autophagy: neuroprotective effects of antiretroviral therapy. FASEB J., 23(9):2928-41.
PMID: 19380511
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Hartl D et al. (2008), Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. J. Immunol., 181(11):8053-67.
PMID: 19017998
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Kerfoot SM et al. (2008), Exogenous stromal cell-derived factor-1 induces modest leukocyte recruitment in vivo. Am. J. Physiol. Heart Circ. Physiol., 294(6):H2524-34.
PMID: 18424631
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Ouwehand K et al. (2008), CXCL12 is essential for migration of activated Langerhans cells from epidermis to dermis. Eur. J. Immunol., 38(11):3050-9.
PMID: 18924211
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Shojaei F et al. (2007), Bv8 regulates myeloid-cell-dependent tumour angiogenesis. Nature, 450(7171):825-31.
PMID: 18064003
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Bayry J et al. (2007), Human dendritic cells acquire a semimature phenotype and lymph node homing potential through interaction with CD4+CD25+ regulatory T cells. J. Immunol., 178(7):4184-93.
PMID: 17371975
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Schreiber TH et al. (2007), Shear flow-dependent integration of apical and subendothelial chemokines in T-cell transmigration: implications for locomotion and the multistep paradigm. Blood, 109(4):1381-6.
PMID: 17038526
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Kaminski A et al. (2007), Endothelial NOS is required for SDF-1alpha/CXCR4-mediated peripheral endothelial adhesion of c-kit+ bone marrow stem cells. Lab. Invest., 88(1):58-69.
PMID: 18040270
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Meyer EH et al. (2007), iNKT cells require CCR4 to localize to the airways and to induce airway hyperreactivity. J. Immunol., 179(7):4661-71.
PMID: 17878364
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Whole Cells
Applications: Bioassay

Isakova IA et al. (2007), Age- and dose-related effects on MSC engraftment levels and anatomical distribution in the central nervous systems of nonhuman primates: identification of novel MSC subpopulations that respond to guidance cues in brain. Stem Cells, 25(12):3261-70.
PMID: 17932418
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Park EJ et al. (2007), Aberrant activation of integrin alpha4beta7 suppresses lymphocyte migration to the gut. J. Clin. Invest., 117(9):2526-38.
PMID: 17786243
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Nakayama T et al. (2006), FGF2 posttranscriptionally down-regulates expression of SDF1 in bone marrow stromal cells through FGFR1 IIIc. Blood, 109(4):1363-72.
PMID: 17077327
Species: N/A
Sample Types: N/A
Applications: ELISA (Standard)

Peng H et al. (2006), HIV-1-infected and/or immune activated macrophages regulate astrocyte SDF-1 production through IL-1beta. Glia, 54(6):619-29.
PMID: 16944452
Species: Virus
Sample Types: Virus
Applications: Binding Assay

Nakayama T et al. (2006), Novel antiviral activity of chemokines. Virology, 350(2):484-92.
PMID: 16603217
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Saunders WB et al. (2006), Coregulation of vascular tube stabilization by endothelial cell TIMP-2 and pericyte TIMP-3. J. Cell Biol., 175(1):179-91.
PMID: 17030988
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Anghelina M et al. (2006), Monocytes/macrophages cooperate with progenitor cells during neovascularization and tissue repair: conversion of cell columns into fibrovascular bundles. Am. J. Pathol., 168(2):529-41.
PMID: 16436667
Species: N/A
Sample Types: N/A
Applications: ELISA (Standard)

Lisignoli G et al. (2006), Hyaluronan-based polymer scaffold modulates the expression of inflammatory and degradative factors in mesenchymal stem cells: Involvement of Cd44 and Cd54. J. Cell. Physiol., 207(2):364-73.
PMID: 16331675
Species: Rat
Sample Types: In Vivo
Applications: In Vivo

Carr AN et al. (2006), Efficacy of systemic administration of SDF-1 in a model of vascular insufficiency: support for an endothelium-dependent mechanism. Cardiovasc. Res., 69(4):925-35.
PMID: 16409996
Species: N/A
Sample Types: N/A
Applications: ELISA (Standard)

Infantino S et al. (2006), Expression and regulation of the orphan receptor RDC1 and its putative ligand in human dendritic and B cells. J. Immunol., 176(4):2197-207.
PMID: 16455976
Species: Rat
Sample Types: In Vivo
Applications: In Vivo

Carr AN et al. (2006), Efficacy of systemic administration of SDF-1 in a model of vascular insufficiency: support for an endothelium-dependent mechanism. Cardiovasc. Res., 69(4):925-35.
PMID: 16409996
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Meller S et al. (2005), Ultraviolet radiation-induced injury, chemokines, and leukocyte recruitment: An amplification cycle triggering cutaneous lupus erythematosus. Arthritis Rheum., 52(5):1504-16.
PMID: 15880822
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Corti S et al. (2005), Multipotentiality, homing properties, and pyramidal neurogenesis of CNS-derived LeX(ssea-1)+/CXCR4+ stem cells. FASEB J., 19(13):1860-2.
PMID: 16150803
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Janardhan A et al. (2004), HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxis. PLoS Biol., 2(1):E6.
PMID: 14737186
Species: N/A
Sample Types: N/A
Applications: ELISA (Standard)

Levesque JP et al. (2004), Characterization of hematopoietic progenitor mobilization in protease-deficient mice. Blood, 104(1):65-72.
PMID: 15010367
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Curiel et al. (2004), Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med, 10(9):942-9.
PMID: 15322536
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Okuma K et al. (2003), Development of a novel surrogate virus for human T-cell leukemia virus type 1: inhibition of infection by osteoprotegerin. J. Virol., 77(15):8562-9.
PMID: 12857926
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Villalba S et al. (2003), Serum inactivation contributes to the failure of stromal-derived factor-1 to block HIV-I infection in vivo. J. Leukoc. Biol., 74(5):880-8.
PMID: 12960279
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Heissig B et al. (2002), Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand. Cell, 109(5):625-37.
PMID: 12062105
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Huber TB et al. (2002), Expression of functional CCR and CXCR chemokine receptors in podocytes. J. Immunol., 168(12):6244-52.
PMID: 12055238
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Zamarchi R et al. (2002), Expression and functional activity of CXCR-4 and CCR-5 chemokine receptors in human thymocytes. 192, 127(2):321-30.
PMID: 11876757
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Misse D et al. (1999), A CD4-independent interaction of human immunodeficiency virus-1 gp120 with CXCR4 induces their cointernalization, cell signaling, and T-cell chemotaxis. Blood, 93(8):2454-62.
PMID: 10194422
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Wellemans V et al. (0), Role of CCR3 in respiratory syncytial virus infection of airway epithelial cells. iScienc24(12):103433.
PMID: 34917892

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Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha

Name: Anonymous

Application: In vitro bioactivity in cell culture

Verified Customer | Posted 01/13/2020
Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha

Name: Anonymous

Application: In vitro bioactivity in cell culture

Verified Customer | Posted 05/27/2019
Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha

Name: Anonymous

Application: Receptor activation by CXCL12 Ligand to screen for NFKB pathway activation by Western Blot: Treat MDA231 cells with CXCL12 to look into whether CXCR4 activation by CXCL12 induced NFkB activation by phosphorylating IkBa by Western Blot

Reason for Rating: Receptor activation by CXCL12 Ligand to screen for NFKB pathway activation by Western Blot: Treat MDA231 cells with CXCL12 to look into whether CXCR4 activation by CXCL12 induced NFkB activation by phosphorylating IkBa by Western Blot

Verified Customer | Posted 03/13/2019
Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha

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Application: Cell migration/motility

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FAQs for Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha

Does Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha Protein (Catalog # 350-NS or Catalog # 350-NS/CF) contain any tags?

Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha Protein (Catalog # 350-NS or Catalog # 350-NS/CF) does not contain any tags. Please refer to the Source section on the product-specific page for sequence information.

Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha

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Background: CXCL12/SDF-1 alpha

Citations for Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha (169)

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