Recombinant Human Nodal Protein
R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Source: | E. coli |
Accession #: | Q96S42 |
Structure / Form: | Disulfide-linked homodimer |
Applications: | Bioactivity |
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Citations for Recombinant Human Nodal Protein (17)
Citations are publications that use Bio-Techne products. Selected citations for Recombinant Human Nodal Protein include:
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Species: Human
Sample Types: Whole Cells
Applications: Cell CultureJ Pérez-Garc et al. (2022), Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration Cancers, 14(16).
PMID: 36011023 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayK Harpelunde et al. (2020), Influence of Nodal signalling on pluripotency factor expression, tumour cell proliferation and cisplatin-sensitivity in testicular germ cell tumours BMC Cancer, 20(1):349.
PMID: 32326899 -
Species: Simian
Sample Types: Whole Cells
Applications: Cell CultureSC Vermilyea et al. (2020), In Vitro CRISPR/Cas9-Directed Gene Editing to Model LRRK2 G2019S Parkinson's Disease in Common Marmosets Sci Rep, 10(1):3447.
PMID: 32103062 -
Species: Chicken
Sample Types: Embryo
Applications: BioassayP Ray et al. (2018), Intrinsic cellular chirality regulates left-right symmetry breaking during cardiac looping Proc. Natl. Acad. Sci. U.S.A., 0(0).
PMID: 30459275 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Jørgensen et al. (2018), Nodal Signaling Regulates Germ Cell Development and Establishment of Seminiferous Cords in the Human Fetal Testis Cell Rep, 25(7):1924-1937.e4.
PMID: 30428358 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Jiang et al. (2017), ALDH enzyme activity is regulated by Nodal and histamine in the A549 cell line Oncol Lett, 14(6):6955-6961.
PMID: 29181106 -
Species: Human
Sample Types: Tissue Homogenates
Applications: BioassayCR Ball et al. (2017), Succession of transiently active tumor-initiating cell clones in human pancreatic cancer xenografts EMBO Mol Med, 0(0).
PMID: 28526679 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTaroh Kinoshita (2016), A GPI processing phospholipase A2, PGAP6, modulates Nodal signaling in embryos by shedding CRIPTO J. Cell Biol., 215(5):705-718.
PMID: 27881714 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayEsquivies L et al. (2014), Designer nodal/BMP2 chimeras mimic nodal signaling, promote chondrogenesis, and reveal a BMP2-like structure. J Biol Chem, 289(3):1788-97.
PMID: 24311780 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayQuail et al. (2014), Nodal promotes invasive phenotypes via a mitogen-activated protein kinase-dependent pathway. Oncogene, 33(4):461-73.
PMID: 23334323 -
Species: Human
Sample Types: Antibody
Applications: Western BlotFuerer C et al. (2014), Nodal.Gdf1 heterodimers with bound prodomains enable serum-independent nodal signaling and endoderm differentiation. J Biol Chem, 289(25):17854-71.
PMID: 24798330 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWilson TR et al. (2012), Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature, 487(7408):505-9.
PMID: 22763448 -
Species: Human
Sample Types: Recombinant Protein
Applications: Surface Plasmon ResonanceCastonguay R et al. (2011), Soluble Endoglin Specifically Binds Bone Morphogenetic Proteins 9 and 10 via Its Orphan Domain, Inhibits Blood Vessel Formation, and Suppresses Tumor Growth. J. Biol. Chem., 286(34):30034-46.
PMID: 21737454 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHerrera B et al. (2009), A rapid and sensitive bioassay for the simultaneous measurement of multiple bone morphogenetic proteins. Identification and quantification of BMP4, BMP6 and BMP9 in bovine and human serum. BMC Cell Biol., 10(0):20.
PMID: 19298647 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWatanabe K et al. (2007), Requirement of glycosylphosphatidylinositol anchor of Cripto-1 for trans activity as a Nodal co-receptor. J. Biol. Chem., 282(49):35772-86.
PMID: 17925387 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMcLean AB et al. (2007), Activin a efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed. Stem Cells, 25(1):29-38.
PMID: 17204604 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWatanabe M et al. (0), TGFbeta superfamily signaling regulates the state of human stem cell pluripotency and capacity to create well-structured telencephalic organoids. Stem Cell Report17(10):2220-2238.
PMID: 36179695
There are no citations that match your criteria.
Customer Reviews for Recombinant Human Nodal Protein (2)
Customer Images
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Application: CellProlifVerified Customer | Posted 10/09/2020
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Application: Stem/Immune cell maintenance or differentiationVerified Customer | Posted 12/06/2018Picture shows my marmoset embryonic stem cells grown with media that is supplemented with this human nodal protein. Cells are healthy, and have a homogenous morphology without spontaneous differentiation
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FAQs for Recombinant Human Nodal Protein
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What is the half-life of this BMP protein?
R&D Systems has not determined the half-life of this recombinant human BMP protein. Assay conditions for each protein will need to be optimized by each researcher.