Recombinant Human MFAP3 Fc Chimera Protein, CF

R&D Systems, part of Bio-Techne | Catalog # 10800-MF

R&D Systems, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
10800-MF-050
Print Quote
Bulk Order
100% Guarantee

Key Product Details

  • R&D Systems HEK293-derived Recombinant Human MFAP3 Fc Chimera Protein (10800-MF)
  • Quality control testing to verify active proteins with lot specific assays by in-house scientists
  • All R&D Systems proteins are covered with a 100% guarantee

Source

HEK293

Accession #

P555082.1

Structure / Form

Disulfide-linked homodimer

Conjugate

Unconjugated

Applications

Bioactivity

View all MFAP3 Proteins and Enzymes »

Product Specifications

Source

Human embryonic kidney cell, HEK293-derived human MFAP3 protein
Human MFAP3
(Leu22-Met147)
Accession # P55082.1		 IEGRMD Human IgG1
(Pro100-Lys330)
N-terminus C-terminus

Purity

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

Endotoxin Level

<0.10 EU per 1 μg of the protein by the LAL method.

N-terminal Sequence Analysis

Leu22

Predicted Molecular Mass

41 kDa

SDS-PAGE

57-67 kDa, under reducing conditions

Activity

Bioassay data are not available.

Scientific Data Images for Recombinant Human MFAP3 Fc Chimera Protein, CF

Recombinant Human MFAP3 Fc Chimera Protein SDS-PAGE.

2 μg/lane of Recombinant Human MFAP3 Fc Chimera (Catalog # 10800-MF) was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by Coomassie® Blue staining, showing bands at 57-67 kDa and 114-134 kDa, respectively.

Formulation, Preparation and Storage

10800-MF
Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution Reconstitute at 500 µg/mL in PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: MFAP3

Microfibril-associated glycoprotein 3 (MFAP3), is a member of the MFAP family which play a role in microfibril assembly, elastinogenesis, and tissue homeostasis. The family members were identified as potential components of fibrillin-containing microfibrils, but they do not share structural similarities (1). MFAP3 is found in ocular zonules. Human MFAP3 is a serine-rich acidic protein located in zonular fibers and consists of an extracellular domain (ECD) containing one Ig-like C2-type domain, a single transmembrane domain, and a cytoplasmic domain. Within the ECD, mature human MFAP3 shares 74% amino acid sequence identity with mouse and rat MFAP3. Among MFAP3-related pathways are degradation of the extracellular matrix and elastic fiber formation. MFAP is a candidate gene for heritable diseases affecting microfibrils (2).

References

  1. Gibson, M.A. Landes Bioscience https://www.ncbi.nlm.nih.gov/books/NBK6448/.
  2. Abrams W.R. (1995) Genomics 26:47.

Long Name

Microfibrillar-Associated Protein 3

Alternate Names

DKFZp586F0219, microfibril-associated glycoprotein 3, microfibrillar-associated protein 3

Entrez Gene IDs

4238 (Human); 216760 (Mouse); 287299 (Rat)

Gene Symbol

MFAP3

UniProt

P555082.1

Additional MFAP3 Products

Product Documents for Recombinant Human MFAP3 Fc Chimera Protein, CF

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Recombinant Human MFAP3 Fc Chimera Protein, CF

For research use only

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.