Recombinant Human Ly6H His-tag Protein, CF
R&D Systems, part of Bio-Techne | Catalog # 10373-L6
Key Product Details
Product Specifications
Source
Chinese Hamster Ovary cell line, CHO-derived human Ly6H protein
Leu26-Gly115, with a C-terminal 6-His tag
Leu26-Gly115, with a C-terminal 6-His tag
Purity
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
N-terminal Sequence Analysis
Leu26
Predicted Molecular Mass
10.7 kDa
SDS-PAGE
13-25 kDa, under reducing conditions
Activity
Measured by its ability to inhibit anti-CD3 antibody induced IL-2 or IFN-gamma secretion by human T cells.
The ED50 for this effect is 0.75-7.5 μg/mL
The ED50 for this effect is 0.75-7.5 μg/mL
Scientific Data Images for Recombinant Human Ly6H His-tag Protein, CF
Recombinant Human Ly6H His-tag Protein SDS-PAGE
2 μg/lane of Recombinant Human Ly6H His-tag Protein (Catalog # 10373-L6) was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by Coomassie® Blue staining, showing bands at 13-25 kDa.Recombinant Human Ly6H His-tag Protein Bioactivity
Measured by its ability to inhibit anti-CD3 antibody induced IL-2 secretion by human T cells. The ED50 for this effect is 0.75-7.5 μg/mL.Formulation, Preparation and Storage
10373-L6
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS. |
Reconstitution | Reconstitute at 200 μg/mL in PBS. |
Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
Background: Ly6H
References
- Upadhyay, G. et al. (2019) Front Immunol. 10:819.
- Puddifoot, C. A. et al. (2015) J Neurosci. 35:3420.
- Govind, A. et al. (2012) J Neurosci. 32:2227.
- Luo, L. et al. (2016) Oncotarget. 7:11165.
Long Name
Lymphocyte Antigen 6 Family Member H
Alternate Names
Ly-6H, NMLy6
Gene Symbol
LY6H
UniProt
Additional Ly6H Products
Product Documents for Recombinant Human Ly6H His-tag Protein, CF
Product Specific Notices for Recombinant Human Ly6H His-tag Protein, CF
For research use only
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