Recombinant Human IL-22 Protein Best Seller

Name: Recombinant Human IL-22 Protein
Brand: R&D Systems
SKU: 782-IL
Price: 421 EUR

Catalog # 782-IL | R&D Systems, Inc. a Bio-Techne Brand

Citations (65)

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E. coli

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Setting the standard in quality research reagents

Key Product Details

Source:	E. coli
Accession #:	Q9GZX6
Applications:	Bioactivity

View Full Technical Details for Recombinant Human IL-22 Protein

Product Specifications for Recombinant Human IL-22 Protein

Source	E. coli-derived human IL-22 protein Ala34-Ile179, with an N-terminal Met
Purity	>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin level	<0.10 EU per 1 μg of the protein by the LAL method.
N-terminal sequence Analysis	Met
Predicted Molecular Mass	16.5 kDa
Activity	Measured by its ability to induce IL-10 secretion in COLO 205 human colorectal adenocarcinoma cells. Nagalakshmi, M.L. et al. (2004) International Immunopharmacology 4:679. The ED₅₀ for this effect is 60-300 pg/mL.

Scientific Data Examples for Recombinant Human IL-22 Protein

	Recombinant Human IL-22 Protein Bioactivity Recombinant Human IL-22 (Catalog # 782-IL) induces IL-10 secretion in the COLO 205 human colorectal adenocarcinoma cell line. The ED₅₀ for this effect is 60-300 pg/mL.
	Recombinant Human IL-22 Protein SDS-PAGE 1 µg/lane of Recombinant Human IL‑22 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 14 kDa.

Formulation, Preparation and Storage

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

782-IL

Carrier

Formulation	Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Reconstitution	Reconstitute at 10 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage:	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

782-IL/CF

Carrier Free

Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	Reconstitute at 100 μg/mL in sterile PBS.
Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage:	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: IL-22

Interleukin-22 (IL-22), also known as IL-10-related T cell-derived inducible factor (IL-TIF) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Human IL-22 cDNA encodes a 179 amino acid (aa) residue protein with a putative 33 aa signal peptide that is cleaved to generate a 147 aa mature protein that shares approximately 79% and 22% aa sequence identity with mouse IL-22 and human IL-10, respectively. The human IL-22 gene is localized to chromosome 12q15. Although it exists as a single copy gene in human and in many mouse strains, the mouse IL-22 gene is duplicated in some mouse strains including C57B1/6, FVB and 129. The two mouse genes designated IL-TIF alpha and IL-TIF beta, share greater than 98% sequence homology in their coding region. IL-22 has been shown to activate STAT‑1 and STAT-3 in several hepatoma cell lines and upregulate the production of acute phase proteins. IL-22 is produced by normal T cells upon anti-CD3 stimulation in humans. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R (previously an orphan receptor named CRF2-9) and IL-10R beta (previously known as CRF2-4), belonging to the class II cytokine receptor family.

Item	Value
References	Dumoutier, L. et al. (2000) J. Immunol. 164:1814. Xie, M-H. et al. (2000) J. Biol. Chem. 275:31335. Dumoutier, L. et al. (2000) PNAS 97:10144. Kotenko, S.V. et al. (2001) J. Biol. Chem. 276:2725.
Long Name	Interleukin 22
Entrez Gene IDs	50616 (Human); 50929 (Mouse); 500836 (Rat)
Alternate Names	Cytokine Zcyto18, IL-10-related T-cell-derived inducible factor, IL-22, IL-D110, IL-TIF, IL-TIFMGC79382, IL22, ILTIFIL-10-related T-cell-derived-inducible factor, MGC79384, TIFIL-23, TIFa, interleukin 22, interleukin-22, zcyto18

Citations for Recombinant Human IL-22 Protein (65)

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Citations are publications that use Bio-Techne products. Selected citations for Recombinant Human IL-22 Protein include:

Species: Human
Sample Types: Whole Cells
Applications: Stimulation

C Maresca et al. (2022-10-12), Smad7 Sustains Stat3 Expression and Signaling in Colon Cancer Cells Cancers, 2022-114(20).
PMID: 36291778
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Segarra et al. (2022-06-27), Enhanced In Vitro Expression of Filaggrin and Antimicrobial Peptides Following Application of Glycosaminoglycans and a Sphingomyelin-Rich Lipid Extract Oncogene, 2022-09(7).
PMID: 35878340
Species: Human
Sample Types: Organoid
Applications: Bioassay

DJ Carroll et al. (2021-12-02), Interleukin-22 regulates B3GNT7 expression to induce fucosylation of glycoproteins in intestinal epithelial cells The Journal of Biological Chemistry, 2021-10(0):101463.
PMID: 34864058
Species: Human
Sample Types: Whole Cell
Applications: Stimulation

L Mercurio et al. (2021-10-02), PI3Kdelta Sustains Keratinocyte Hyperproliferation and Epithelial Inflammation: Implications for a Topically Druggable Target in Psoriasis Cells, 2021-110(10).
PMID: 34685616
Species: Human
Sample Types: Whole Cell
Applications: Stimulation

F Abdallah et al. (2021-09-26), miR-21-3p/IL-22 Axes Are Major Drivers of Psoriasis Pathogenesis by Modulating Keratinocytes Proliferation-Survival Balance and Inflammatory Response Cells, 2021-010(10).
PMID: 34685526
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

HC Hawerkamp et al. (2021-05-21), Tofacitinib downregulates antiviral immune defence in keratinocytes and reduces T cell activation Arthritis Research Therapy, 2021-05-21;23(1):144.
PMID: 34020693
Species: Human
Sample Types: Reference Standard

HK Min et al. (2020-09-23), Interleukin (IL)-25 suppresses IL-22-induced osteoclastogenesis in rheumatoid arthritis via STAT3 and p38 MAPK/I&kappaB&alpha pathway Arthritis Research Therapy, 2020-09-23;22(1):222.
PMID: 32972460
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay

EY Kim et al. (2019-12-06), Interleukin-22 Induces the Infiltration of Visceral Fat Tissue by a Discrete Subset of Duffy Antigen Receptor for Chemokine-Positive M2-Like Macrophages in Response to a High Fat Diet Cells, 2019-18(12).
PMID: 31817755
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

X Xu et al. (2019-11-06), The Link between Type III Reg and STAT3-Associated Cytokines in Inflamed Colonic Tissues Mediators Inflamm., 2019-12019(0):7859460.
PMID: 31780871
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

KD Hebert et al. (2019-10-09), Targeting the IL-22/IL-22BP axis enhances tight junctions and reduces inflammation during influenza infection Mucosal Immunol, 2019-10(0).
PMID: 31597930
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JC Chamcheu et al. (2019-09-15), Fisetin, a 3,7,3',4'-Tetrahydroxyflavone Inhibits the PI3K/Akt/mTOR and MAPK Pathways and Ameliorates Psoriasis Pathology in 2D and 3D Organotypic Human Inflammatory Skin Models Cells, 2019-08(9).
PMID: 31540162
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

S Sugihara et al. (2019-08-21), TNF-Î± and IL-17A induce the expression of lympho-epithelial Kazal-type inhibitor in epidermal keratinocytes J. Dermatol. Sci., 2019-00(0).
PMID: 31501002
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

H Lindahl et al. (2019-07-10), IL-22 Binding Protein Promotes the Disease Process in Multiple Sclerosis J. Immunol., 2019-00(0).
PMID: 31292217
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Sun et al. (2019-03-20), Berberine downregulates CDC6 and inhibits proliferation via targeting JAK-STAT3 signaling in keratinocytes Cell Death Dis, 2019-010(4):274.
PMID: 30894513
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

F Abdallah et al. (2019-03-11), R. nukuhivensis acts by reinforcing skin barrier function, boosting skin immunity and by inhibiting IL-22 induced keratinocyte hyperproliferation Sci Rep, 2019-09(1):4132.
PMID: 30858525
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JE Heath et al. (2019-03-08), IL-36? regulates mediators of tissue homeostasis in epithelial cells Cytokine, 2019-0119(0):24-31.
PMID: 30856602
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

L Mercurio et al. (2018-10-30), IL-38 has an anti-inflammatory action in psoriasis and its expression correlates with disease severity and therapeutic response to anti-IL-17A treatment Cell Death Dis, 2018-19(11):1104.
PMID: 30377293
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Abikhair B et al. (2018-09-06), Ruxolitinib inhibits cyclosporine-induced proliferation of cutaneous squamous cell carcinoma JCI Insight, 2018-03(17).
PMID: 30185657
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

BA Stanfield et al. (2018-04-11), Intramuscular vaccination of guinea pigs with the live-attenuated human herpes simplex vaccine VC2 stimulates a transcriptional profile of vaginal Th17 and regulatory Tr1 responses Vaccine, 2018-00(0).
PMID: 29655629
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

L Bin et al. (2018-01-31), ANKRD1 regulates innate immune responses against herpes simplex virus 1: A potential role in eczema herpeticum J. Allergy Clin. Immunol., 2018-00(0).
PMID: 29371118
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

S Abadpour et al. (2018-01-12), Interleukin-22 reverses human islet dysfunction and apoptosis triggered by hyperglycemia and LIGHT J. Mol. Endocrinol., 2018-00(0).
PMID: 29330151
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Sawamura et al. (2017-12-29), Regulatory mechanisms of collagen expression by interleukin-22 signaling in scleroderma fibroblasts J. Dermatol. Sci., 2017-10(0).
PMID: 29336866
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

R Bichele et al. (2017-12-11), IL-22 neutralizing autoantibodies impair fungal clearance in murine oropharyngeal candidiasis model Eur. J. Immunol., 2017-10(0).
PMID: 29150834
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Tohyama et al. (2017-11-20), Bcl-3 induced by IL-22 via STAT3 activation acts as a potentiator of psoriasis-related gene expression in epidermal keratinocytes Eur. J. Immunol., 2017-10(0).
PMID: 28901004
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Y Wang et al. (2017-09-22), IL-22 Increases Permeability of Intestinal Epithelial Tight Junctions by Enhancing Claudin-2 Expression J. Immunol., 2017-00(0).
PMID: 28939759
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

E Couderc et al. (2017-07-14), Interleukin-17A-induced production of acute serum amyloid A by keratinocytes contributes to psoriasis pathogenesis PLoS ONE, 2017-012(7):e0181486.
PMID: 28708859
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Y Kim et al. (2017-05-30), The pathogenic role of interleukin-22 and its receptor during UVB-induced skin inflammation PLoS ONE, 2017-012(5):e0178567.
PMID: 28558005
Species: Human
Sample Types: Recombinant Protein, Whole Cells
Applications: Bioassay, Surface Plasmon Resonance

S La Manna et al. (2017-05-04), Characterization of linear mimetic peptides of Interleukin-22 from dissection of protein interfaces Biochimie, 2017-00(0).
PMID: 28479106
Applications: ELISA (Standard)

J Zhang et al. (2017-03-17), Machine-learning algorithms define pathogen-specific local immune fingerprints in peritoneal dialysis patients with bacterial infections Kidney Int, 2017-00(0).
PMID: 28318629
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JS Ainscough et al. (2017-03-13), Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36? Proc. Natl. Acad. Sci. U.S.A, 2017-0114(13):E2748-E2757.
PMID: 28289191
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Robert Sabat (2016-10-23), MMP8 Is Increased in Lesions and Blood of Acne Inversa Patients: A Potential Link to Skin Destruction and Metabolic Alterations Mediators Inflamm., 2016-12016(0):4097574.
PMID: 27843200
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016-09-23), JAK2 Disease-Risk Variants Are Gain of Function and JAK Signaling Threshold Determines Innate Receptor-Induced Proinflammatory Cytokine Secretion in Macrophages J Immunol, 2016-00(0).
PMID: 27664279
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016-09-02), Impaired Tight Junctions in Atopic Dermatitis Skin and in a Skin-Equivalent Model Treated with Interleukin-17 PLoS ONE, 2016-011(9):e0161759.
PMID: 27588419
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

OB Corneth et al. (2016-05-12), Loss of IL-22 inhibits autoantibody formation in collagen-induced arthritis in mice Eur J Immunol, 2016-00(0).
PMID: 27067635
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016-05-11), The Role of Interleukin-22 and Its Receptor in the Development and Pathogenesis of Experimental Autoimmune Uveitis PLoS ONE, 2016-011(5):e0154904.
PMID: 27166675
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Perriard G et al. (2015-06-16), Interleukin-22 is increased in multiple sclerosis patients and targets astrocytes. J Neuroinflammation, 2015-012(0):119.
PMID: 26077779
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Akil H et al. (2015-03-20), IL22/IL-22R pathway induces cell survival in human glioblastoma cells. PLoS ONE, 2015-010(3):e0119872.
PMID: 25793261
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Banas M et al. (2015-02-06), The expression and regulation of chemerin in the epidermis. PLoS ONE, 2015-010(2):e0117830.
PMID: 25659101
Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
Sample Types: Whole Cells
Applications: Bioassay

Shen H et al. (2015-02-01), Th17-related cytokines contribute to recall-like expansion/effector function of HMBPP-specific Vgamma2Vdelta2 T cells after Mycobacterium tuberculosis infection or vaccination. Eur J Immunol, 2015-045(2):442-51.
PMID: 25141829
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Sugita S et al. (2015-01-20), Inhibition of T-cell activation by retinal pigment epithelial cells derived from induced pluripotent stem cells. Invest Ophthalmol Vis Sci, 2015-056(2):1051-62.
PMID: 25604685
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

De Simone V et al. (2014-09-01), Th17-type cytokines, IL-6 and TNF-alpha synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth. Oncogene, 2014-034(27):3493-503.
PMID: 25174402
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Rabeony H et al. (2014-07-10), Inhibition of keratinocyte differentiation by the synergistic effect of IL-17A, IL-22, IL-1alpha, TNFalpha and oncostatin M. PLoS ONE, 2014-09(7):e101937.
PMID: 25010647
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Sakaguchi M et al. (2014-07-07), DNAX-activating protein 10 (DAP10) membrane adaptor associates with receptor for advanced glycation end products (RAGE) and modulates the RAGE-triggered signaling pathway in human keratinocytes. J Biol Chem, 2014-0289(34):23389-402.
PMID: 25002577
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Chen J et al. (2014-05-13), IL-22 negatively regulates Helicobacter pylori-induced CCL20 expression in gastric epithelial cells. PLoS ONE, 2014-09(5):e97350.
PMID: 24824519
Sample Types: N/A
Applications: Western Blot

Beigel F et al. (2014-04-07), Oncostatin M mediates STAT3-dependent intestinal epithelial restitution via increased cell proliferation, decreased apoptosis and upregulation of SERPIN family members. PLoS ONE, 2014-09(4):e93498.
PMID: 24710357
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Madonna S et al. (2013-05-28), Therapeutical potential of a peptide mimicking the SOCS1 kinase inhibitory region in skin immune responses. Eur J Immunol, 2013-043(7):1883-95.
PMID: 23592500
Species: Human
Sample Types: Plasma
Applications: Bioassay

Rosen L et al. (2013-03-18), Anti-GM-CSF autoantibodies in patients with cryptococcal meningitis. J Immunol, 2013-0190(8):3959-66.
PMID: 23509356
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Pennino D et al. (2012-11-19), IL-22 suppresses IFN-gamma-mediated lung inflammation in asthmatic patients. J Allergy Clin Immunol, 2012-1131(2):562-70.
PMID: 23174657
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Ramirez-Carrozzi V et al. (2011-10-12), IL-17C regulates the innate immune function of epithelial cells in an autocrine manner. Nat. Immunol., 2011-112(12):1159-66.
PMID: 21993848
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Chang Y et al. (2011-02-22), TH17 cytokines induce human airway smooth muscle cell migration. J. Allergy Clin. Immunol., 2011-0127(4):1046-53.e1-2.
PMID: 21345484
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Johnston A et al. (2011-01-17), IL-1F5, -F6, -F8, and -F9: A Novel IL-1 Family Signaling System That Is Active in Psoriasis and Promotes Keratinocyte Antimicrobial Peptide Expression. J. Immunol., 2011-0186(4):2613-22.
PMID: 21242515
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Gudjonsson JE et al. (2010-04-08), Evidence for altered Wnt signaling in psoriatic skin. J. Invest. Dermatol., 2010-0130(7):1849-59.
PMID: 20376066
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Guilloteau K et al. (2010-03-24), Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1alpha, and TNF-alpha Recapitulates Some Features of Psoriasis. J. Immunol., 2010-0184(0):5263-70.
PMID: 20335534
Species: Human
Sample Types: Serum
Applications: ELISA (Capture)

Kisand K et al. (2010-02-01), Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines. J. Exp. Med., 2010-0207(2):299-308.
PMID: 20123959
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Wolk K et al. (2009-12-01), The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis. Eur. J. Immunol., 2009-139(12):3570-81.
PMID: 19830738
Sample Types: N/A
Applications: ELISA (Standard)

Heo YJ et al. (2009-11-04), IL-10 suppresses Th17 cells and promotes regulatory T cells in the CD4+ T cell population of rheumatoid arthritis patients. Immunol. Lett., 2009-1127(2):150-6.
PMID: 19895848
Species: Human
Sample Types: Buffer
Applications: Bioassay

Witte K et al. (2009-10-01), Despite IFN-lambda receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: implications for therapeutic applications of these cytokines. Genes Immun., 2009-110(8):702-14.
PMID: 19798076
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tohyama M et al. (2009-10-01), IL-17 and IL-22 mediate IL-20 subfamily cytokine production in cultured keratinocytes via increased IL-22 receptor expression. Eur. J. Immunol., 2009-139(10):2779-88.
PMID: 19731362
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Kinoshita H et al. (2008-12-03), Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA. J. Allergy Clin. Immunol., 2008-1123(1):179-86.
PMID: 19056108
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Guttman-Yassky E et al. (2008-11-15), Low expression of the IL-23/Th17 pathway in atopic dermatitis compared to psoriasis. J. Immunol., 2008-1181(10):7420-7.
PMID: 18981165
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Aujla SJ et al. (2008-02-10), IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia. Nat. Med., 2008-014(3):275-81.
PMID: 18264110
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dambacher J et al. (2008-01-11), The role of interleukin-22 in hepatitis C virus infection. Cytokine, 2008-041(3):209-16.
PMID: 18191408
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Sa SM et al. (2007-02-15), The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis. J. Immunol., 2007-0178(4):2229-40.
PMID: 17277128
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Wolk K et al. (2006-05-01), IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis. Eur. J. Immunol., 2006-036(5):1309-23.
PMID: 16619290
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Herrero C et al. (2003-11-15), Reprogramming of IL-10 activity and signaling by IFN-gamma. J. Immunol., 2003-1171(10):5034-41.
PMID: 14607900

Recombinant Human IL-22 Protein Best Seller

Catalog # 782-IL | R&D Systems, Inc. a Bio-Techne Brand

Key Product Details

Customers also Viewed

Product Specifications for Recombinant Human IL-22 Protein

Scientific Data Examples for Recombinant Human IL-22 Protein

Formulation, Preparation and Storage

Carrier Free

782-IL

Carrier

782-IL/CF

Carrier Free

Reconstitution Calculator

Background: IL-22

Citations for Recombinant Human IL-22 Protein (65)

Product Documents for Recombinant Human IL-22 Protein

Product Datasheets

COA

Certificate of Analysis

SDS

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