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Recombinant Human Carbonic Anhydrase VI Protein, CF

Bio-Techne includes R&D Systems | Catalog # 2939-CA

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Enzyme Activity

Product Specifications


Mouse myeloma cell line, NS0-derived human Carbonic Anhydrase VI protein
Gln18-Asn308, with a C-terminal 10-His tag


>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

Endotoxin Level

<1.0 EU per 1 μg of the protein by the LAL method.

N-terminal Sequence Analysis

No results obtained: Gln18 predicted

Predicted Molecular Mass

35 kDa


42 kDa, reducing conditions


Measured by its esterase activity.
The specific activity is >3 pmol/min/µg, as measured under the described conditions.

Formulation, Preparation and Storage

Formulation Supplied as a 0.2 μm filtered solution in Tris, NaCl, Brij and Glycerol.
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Do not freeze.
  • 3 months from date of receipt, 2 to 8 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after opening.

Background: Carbonic Anhydrase VI

Carbonic Anhydrase catalyzes the reversible reaction of CO2 + H2O = HCO3- + H+, which is fundamental to many processes such as respiration, renal tubular acidification and bone resorption (1). Topics in a CA meeting (6th International Conference on the CAs, June 20‑25, 2003, Slovakia) ranged from the use of CAs as markers for tumor and hypoxia in the clinic, as a nutritional supplement in milk, and as a tool for CO2 removal and mosquito control in industry. Carbonic Anhydrase VI, also known as gustin and salivary Carbonic Anhydrase, is a zinc-metalloprotein that constitutes about 3% of human parotid saliva protein (2, 3). It was decreased in patients with loss of taste and pathological changes in taste buds (4). It is also an elementary component of milk. It plays an important role in normal growth and development of the infant alimentary tract (5).


  1. Hewett-Emmett, D. and R.E. Tashian (1996) Mol. Phylogenet. Evol. 5:50.
  2. Murakami, H. and Sly, W. S. (1987) J. Biol. Chem. 262:1382.
  3. Thatcher, B. J. et al. (1998) Biochem. Biophys. Res. Commun. 250:635.
  4. Hankin, R. I. et al. (1999) Am. J. Med. Sci. 318:380.
  5. Karhumaa, P. et al. (2001) Proc. Natl. Acad. Sci. USA. 98:11604.

Alternate Names

CA6, Gustin

Entrez Gene IDs

765 (Human); 298657 (Rat)

Gene Symbol



Additional Carbonic Anhydrase VI Products

Product Documents for Recombinant Human Carbonic Anhydrase VI Protein, CF

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Recombinant Human Carbonic Anhydrase VI Protein, CF

For research use only