Recombinant Human PGR1 His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-98897

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NBP1-98897-100ug
NBP1-98897-0.5mg
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Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all PGR1 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-329 of Human PGR1

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSEFMVRTK TWTLKKHFVG YPTNSDFELK TAELPPLKNG EVLLEALFLT VDPYMRVAAK RLKEGDTMMG QQVAKVVESK NVALPKGTIV LASPGWTTHS ISDGKDLEKL LTEWPDTIPL SLALGTVGMP GLTAYFGLLE ICGVKGGETV MVNAAAGAVG SVVGQIAKLK GCKVVGAVGS DEKVAYLQKL GFDVVFNYKT VESLEETLKK ASPDGYDCYF DNVGGEFSNT VIGQMKKFGR IAICGAISTY NRTGPLPPGP PPEIVIYQEL RMEAFVVYRW QGDARQKALK DLLKWVLEGK IQYKEYIIEG FENMPAAFMG MLKGDNLGKT IVKA

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

38.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human PGR1 His Protein

SDS-PAGE: Recombinant Human PGR1 His Protein [NBP1-98897]

SDS-PAGE: Recombinant Human PGR1 His Protein [NBP1-98897]

SDS-Page: Recombinant Human PGR1 Protein [NBP1-98897] - 15% SDS-PAGE (3ug)

Formulation, Preparation and Storage

NBP1-98897
Formulation 20 mM Tris-HCl buffer (pH7.5), 10% glycerol, 1 mM DTT, 200 mM NaCl
Preservative No Preservative
Concentration 0.5 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PGR1

PTGR1, also known as LTB4DH, belongs to the NADP-dependent oxidoreductase L4BD family. This enzyme catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4. It is highly expressed in the kidney, liver, and intestine but not in leukocytes. Recombinant human PTGR1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

15-oxoprostaglandin 13-reductase, EC 1.3.1.-, EC 1.3.1.48, EC 1.3.1.74, FLJ99229, leukotriene B4 12-hydroxydehydrogenase, LTB4DH, MGC34943, NADP-dependent leukotriene B4 12-hydroxydehydrogenase, PGR1, PRG-1, prostaglandin reductase 1, ZADH3, zinc binding alcohol dehydrogenase domain containing 3

Gene Symbol

PTGR1

Additional PGR1 Products

Product Documents for Recombinant Human PGR1 His Protein

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Recombinant Human PGR1 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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