Recombinant Human PA28 Activator beta Subunit/PSME2 His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-72527

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NBP1-72527-250ug
NBP1-72527-50ug
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Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all PA28 Activator beta Subunit Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-239 of Human PA28 Activator beta Subunit/PSME2

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MAKPCGVRLS GEARKQVEVF RQNLFQEAEE FLYRFLPQKI IYLNQLLQED SLNVADLTSL RAPLDIPIPD PPPKDDEMET DKQEKKEVPK CGFLPGNEKV LSLLALVKPE VWTLKEKCIL VITWIQHLIP KIEDGNDFGV AIQEKVLERV NAVKTKVEAF QTTISKYFSE RGDAVAKASK ETHVMDYRAL VHERDEAAYG ELRAMVLDLR AFYAELYHII SSNLEKIVNP KGEEKPSMY

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

29.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human PA28 Activator beta Subunit/PSME2 His Protein

SDS-PAGE: Recombinant Human PA28 Activator beta Subunit/PSME2 His Protein [NBP1-72527]

SDS-PAGE: Recombinant Human PA28 Activator beta Subunit/PSME2 His Protein [NBP1-72527]

SDS-Page: Recombinant Human PA28 Activator beta Subunit/PSME2 His Protein [NBP1-72527] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Formulation, Preparation and Storage

NBP1-72527
Formulation 20 mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1 M NaCl, 1 mM DTT, 0.1 mM PMSF
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PA28 Activator beta Subunit

PSME2, also known as proteasome (prosome, macropain) activator subunit 2, is an IFN-gamma inducible proteasome activator required for presentation of certain major histocompatibility (MHC) class I antigens. Downregulation of PSME2 results in abnormal proteasome activation and has been implicated in the development of intimal hyperplasia (IH) in animal models. Recombinant human PSME2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Long Name

Proteasome (Prosome, Macropain) Activator Subunit 2

Alternate Names

MCP Activator, PSME2

Gene Symbol

PSME2

Additional PA28 Activator beta Subunit Products

Product Documents for Recombinant Human PA28 Activator beta Subunit/PSME2 His Protein

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Recombinant Human PA28 Activator beta Subunit/PSME2 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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