Recombinant Human NEIL2 His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-99001

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Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all NEIL2 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-332 of Human NEIL2

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMPEGPL VRKFHHLVSP FVGQQVVKTG GSSKKLQPAS LQSLWLQDTQ VHGKKLFLRF DLDEEMGPPG SSPTPEPPQK EVQKEGAADP KQVGEPSGQK TLDGSSRSAE LVPQGEDDSE YLERDAPAGD AGRWLRVSFG LFGSVWVNDF SRAKKANKRG DWRDPSPRLV LHFGGGGFLA FYNCQLSWSS SPVVTPTCDI LSEKFHRGQA LEALGQAQPV CYTLLDQRYF SGLGNIIKNE ALYRAGIHPL SLGSVLSASR REVLVDHVVE FSTAWLQGKF QGRPQHTQVY QKEQCPAGHQ VMKEAFGPED GLQRLTWWCP QCQPQLSEEP EQCQFS

Purity

>85%, by SDS-PAGE

Predicted Molecular Mass

39.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human NEIL2 His Protein

Recombinant Human NEIL2 Protein [NBP1-99001]

Formulation, Preparation and Storage

NBP1-99001
Formulation 20 mM Tris-HCl buffer (pH 8.0), 1 mM DTT, 10% glycerol, 0.1 M NaCl
Preservative No Preservative
Concentration 0.5 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NEIL2

Endonuclease 8-like 2, also known as NEIL2, belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction. It has negligible or undetectable activity with 8-oxoguanine, thymine glycol, 2-hydroxyadenine, hypoxanthine, and xanthine. Recombinant human NEIL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

DNA glycosylase/AP lyase Neil2, EC 3.2.2.-, EC 4.2.99.18, endonuclease 8-like 2, Endonuclease VIII-like 2, FLJ31644, MGC2832, MGC4505, NEH2DNA-(apurinic or apyrimidinic site) lyase Neil2, nei endonuclease VIII-like 2 (E. coli), Nei homolog 2, nei like 2, nei like 2 (E. coli), NEI2, Nei-like protein 2

Gene Symbol

NEIL2

Additional NEIL2 Products

Product Documents for Recombinant Human NEIL2 His Protein

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Recombinant Human NEIL2 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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