Recombinant Human KAT2A/GCN5 His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-72426

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Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

Functional Assay, SDS-PAGE

View all KAT2A/GCN5 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 411-837 of Human KAT2A/GCN5

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGGGSNSSLS LDSAGAEPMP GEKRTLPENL TLEDAKRLRV MGDIPMELVN EVMLTITDPA AMLGPETSLL SANAARDETA RLEERRGIIE FHVIGNSLTP KANRRVLLWL VGLQNVFSHQ LPRMPKEYIA RLVFDPKHKT LALIKDGRVI GGICFRMFPT QGFTEIVFCA VTSNEQVKGY GTHLMNHLKE YHIKHNILYF LTYADEYAIG YFKKQGFSKD IKVPKSRYLG YIKDYEGATL MECELNPRIP YTELSHIIKK QKEIIKKLIE RKQAQIRKVY PGLSCFKEGV RQIPVESVPG IRETGWKPLG KEKGKELKDP DQLYTTLKNL LAQIKSHPSA WPFMEPVKKS EAPDYYEVIR FPIDLKTMTE RLRSRYYVTR KLFVADLQRV IANCREYNPP DSEYCRCASA LEKFFYFKLK EGGLIDK

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

51.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Application Notes

Use in In vitro reported in scientific literature (PMID:33279621).

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human KAT2A/GCN5 His Protein

Recombinant Human KAT2A/GCN5 Protein [NBP1-72426]

Formulation, Preparation and Storage

NBP1-72426
Formulation 20 mM Tris-HCl buffer (pH 8.0), 5mM DTT, 40% glycerol, 200 mM NaCl, 1 mM EDTA
Preservative No Preservative
Concentration 0.25 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: KAT2A/GCN5

GCN5L2(General control of amino acid synthesis protein 5 like 2) belongs to the GCN5 family. It functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. GCN5L2 has been shown to interact with Ku70, TAF9, transcription initiation protein SPT3 homolog, TADA2L, Ku80 and DDB1. Recombinant human GCN5L2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Long Name

Lysine Acetyltransferase 2A

Alternate Names

GCN5L2, HGCN5, KAT2A, PCAF-B

Gene Symbol

KAT2A

Additional KAT2A/GCN5 Products

Product Documents for Recombinant Human KAT2A/GCN5 His Protein

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Recombinant Human KAT2A/GCN5 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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