Recombinant Human Calsenilin His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-50875

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NBP1-50875-0.1mg
NBP1-50875-0.5mg
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Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all Calsenilin Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-256 of Human Calsenilin

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MQPAKEVTKA SDGSLLGDLG HTPLSKKEGI KWQRPRLSRQ ALMRCCLVKW ILSSTAPQGS DSSDSELELS TVRHQPEGLD QLQAQTKFTK KELQSLYRGF KNECPTGLVD EDTFKLIYAQ FFPQGDATTY AHFLFNAFDA DGNGAIHFED FVVGLSILLR GTVHEKLKWA FNLYDINKDG YITKEEMLAI MKSIYDMMGR HTYPILREDA PAEHVERFFE KMDRNQDGVV TIEEFLEACQ KDENIMSSMQ LFENVI

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

31.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human Calsenilin His Protein

SDS-PAGE: Recombinant Human Calsenilin His Protein [NBP1-50875]

SDS-PAGE: Recombinant Human Calsenilin His Protein [NBP1-50875]

SDS-Page: Recombinant Human Calsenilin Protein [NBP1-50875] - 15 % SDS-PAGE (3ug)

Formulation, Preparation and Storage

NBP1-50875
Formulation 20 mM Tris-HCl buffer (pH 8.0), 10% glycerol, 2 mM DTT, 0.1 M NaCl
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Calsenilin

KCNIP3 is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins containing EF-hand-like domains. This protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease. Recombinant human KCNIP3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

calsenilin, calsenilin, presenilin-binding protein, EF hand transcription factor, CSEN MGC18289, DREAM, DREAMA-type potassium channel modulatory protein 3, KChIP3, KCHIP3 DRE-antagonist modulator, Kv channel interacting protein 3, calsenilin, Kv channel-interacting protein 3, potassium channel interacting protein 3

Gene Symbol

KCNIP3

Additional Calsenilin Products

Product Documents for Recombinant Human Calsenilin His Protein

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Recombinant Human Calsenilin His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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