Recombinant Avian Influenza A H7N9 Hemagglutinin (A/Anhui/1-BALF_RG45/2013) His Protein

Name: Recombinant Avian Influenza A H7N9 Hemagglutinin (A/Anhui/1-BALF_RG45/2013) His Protein
Brand: Novus Biologicals
SKU: NBP3-11850

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-11850

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Key Product Details

Source

Baculovirus

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all Avian Influenza A H7N9 Hemagglutinin Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a His-tag and corresponding to the amino acids 19-339 of Avian Influenza A H7N9 Hemagglutinin.

Source: Baculovirus

Amino Acid Sequence: ADL DKICLGH HAVSNGTKVN TLTERGVEVV NATETVERTN IPRICSKGKR TVDLGQCGLL GTITGPPQCD QFLEFSADLI IERREGSDVC YPGKFVNEEA LRQILRESGG IDKEAMGFTY SGIRTNGATS ACRRSGSSFY AEMKWLLSNT DNAAFPQMTK SYKNTRKSPA LIVWGIHHSV STAEQTKLYG SGNKLVTVGS SNYQQSFVPS PGARPQVNGL SGRIDFHWLM LNPNDTVTFS FNGAFIAPDR ASFLRGKSMG IQSGVQVDAN CEGDCYHSGG TIISNLPFQN IDSRAVGKCP RYVKQRSLLL ATGMKNVPEI PKGR

Purity

>95%, by SDS-PAGE

Endotoxin Level

< 1 EU per 1ug of protein (determined by LAL method)

Predicted Molecular Mass

36 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images

SDS-PAGE: Recombinant Avian Influenza A H7N9 Hemagglutinin (A/Anhui/1-BALF_RG45/2013) His Protein [NBP3-11850]

SDS-Page: Recombinant Avian Influenza A H7N9 Hemagglutinin His Protein [NBP3-11850] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

Formulation, Preparation and Storage

NBP3-11850

Formulation	PBS (pH 7.4), 10% glycerol
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Avian Influenza A H7N9 Hemagglutinin

H7N9/HA (hemaggulutinin1) belongs to the influenza viruses hemagglutinin family. Influenza A virus subtype H7N9 (A/H7N9) is a bird flu strain of the species Influenza virus A Influenza and Influenza hemagglutinin (HA) or haemagglutinin is a type of hemagglutinin found on the surface of the influenza viruses. An H7N9 virus was first reported to have infected humans in March 2013, in China. The CDC estimates that the H7N9 virus has the greatest potential compared with other influenza A viruses to cause a pandemic, although the risk is low, because like other type A viruses, it is not easily transmitted between people in its current form. H7N9/HA is an antigenic glycoprotein and is responsible for binding the virus to the cell that is being infected. HA protein has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding of these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of host endosomal membrane with the viral membrane. Recombinant Influenza A virus (A/Anhui/1-BALF_RG45/2013(H7N9)) HA1 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternate Names

H7N9HA

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Product Specific Notices

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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