Naloxone fluorescein acetate
Tocris Bioscience, part of Bio-Techne | Catalog # 6046
Fluorescent opioid antagonist; fluorescent-derivative of naloxone (Cat. No. 0599)
Discontinued Product
6046 has been discontinued.
View all Fluorescent Receptor Probes products.
Key Product Details
Description
Fluorescent opioid antagonist; fluorescent-derivative of naloxone (Cat. No. 0599)
Product Description
Naloxone fluorescein acetate is a fluorescent opioid antagonist; fluorescent derivative of naloxone (Cat. No. 0599). Excitation\emission λ ~ 492\517 nm at pH 10.Spectra Viewer
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Product Specifications
Molecular Weight
790.84
Formula
C40H34N4O8S.C2H4O2
Storage
Store at -20°C
Chemical Name
N-(3',6'-Dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)-2-[(5α)-4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-ylidene]hydrazinecarbothioamide acetate
CAS Number
2080300-52-1
PubChem ID
122705994
InChI Key
DRNYJSGWOSUNLJ-KYTOOIOKSA-N
SMILES
[H][C@@]12OC3=C(C=CC4=C3[C@@]15CCN([C@](C4)([C@@]5(CC/C2=N\NC(NC6=CC=C7C(C(OC78C9=CC=C(C=C9OC%10=CC(O)=CC=C8%10)O)=O)=C6)=S)O)[H])CC=C)O.CC(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 0.5 |
Preparing Stock Solutions
for Naloxone fluorescein acetate
The following data is based on the product molecular weight 790.84
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.01 mM | 126.45 mL | 632.24 mL | 1,264.48 mL |
| 0.05 mM | 25.29 mL | 126.45 mL | 252.90 mL |
| 0.1 mM | 12.64 mL | 63.22 mL | 126.45 mL |
| 0.5 mM | 2.53 mL | 12.64 mL | 25.29 mL |
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Background References
References are publications that support the biological activity of the product.
- Friesen Opioid receptor activation triggering downregulation of cAMP improves effectiveness of anti-cancer drugs in treatment of glioblastoma. Cell Cycle 2014 PMID: 24626197
Product Specific Notices for Naloxone fluorescein acetate
For research use only
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