ML 9 hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 0431

Myosin light chain kinase inhibitor
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Key Product Details

Description

Myosin light chain kinase inhibitor

View all Myosin Light Chain Kinase Inhibitors »

Product Description

ML 9 hydrochloride is a selective MLCK inhibitor (Ki values are 4, 32 and 54 μM for MLCK, PKA and PKC respectively). Also inhibits STIM1-plasma membrane interactions, preventing store-operated Ca2+ entry (SOCE).

Product Specifications

Molecular Weight

361.29

Formula

C15H17ClN2O2S.HCl

Storage

Desiccate at RT

Purity

≥98% (HPLC)

Chemical Name

1-(5-Chloronaphthalenesulfonyl)homopiperazine hydrochloride

CAS Number

105637-50-1

PubChem ID

108047

InChI Key

ZNRYCIVTNLZOGI-UHFFFAOYSA-N

SMILES

Cl.ClC1=C2C=CC=C(C2=CC=C1)S(=O)(=O)N1CCCNCC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 9.03 25

Preparing Stock Solutions for ML 9 hydrochloride

The following data is based on the product molecular weight 361.29

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.25 mM 11.07 mL 55.36 mL 110.71 mL
1.25 mM 2.21 mL 11.07 mL 22.14 mL
2.5 mM 1.11 mL 5.54 mL 11.07 mL
12.5 mM 0.22 mL 1.11 mL 2.21 mL

Calculators

Molarity Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for ML 9 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for ML 9 hydrochloride

For research use only

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