MRS 2693 trisodium salt
Tocris Bioscience, part of Bio-Techne | Catalog # 2502
Selective P2Y6 agonist
Key Product Details
Description
Selective P2Y6 agonist
Alternative Names
5-Iodo-UDP trisodium salt
Product Description
MRS 2693 trisodium salt is a selective P2Y6 agonist (EC50 = 0.015 μM at the hP2Y6 receptor). Displays no activity at other P2Y subtypes. Exerts a cytoprotective effect in an in vivo mouse model of hindlimb skeletal muscle ischemia/reperfusion injury.Product Specifications
Molecular Weight
596.00
Formula
C9H10IN2Na3O12P2
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
5-Iodouridine-5'-O-diphosphate trisodium salt
CAS Number
1448858-83-0
PubChem ID
90488768
InChI Key
QWGVSYFNEAILDQ-FCIXCQMASA-K
SMILES
[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])([O-])=O)N1C=C(I)C(=O)NC1=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble in water (supplied pre-dissolved at a concentration of 10mM) |
Calculators
Molarity Calculator
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Background References
References are publications that support the biological activity of the product.
- Mamedova Attenuation of apoptosis in vitro and ischemia/reperfusion injury in vivo in mouse skeletal muscle by P2Y6 receptor activation. Pharmacol.Res. 2008 PMID: 18805489
- Jacobson Development of selective agonists and antagonists of P2Y receptors. Purinerg.Sig.
- Besada Structure-activity relationships of uridine 5'-diphosphate analogues at the human P2Y6 receptor. J.Med.Chem. 2006 PMID: 16942026
Product Specific Notices for MRS 2693 trisodium salt
For research use only
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