NCH 51

Name: NCH 51
Brand: Tocris Bioscience
SKU: 3747

Tocris Bioscience, part of Bio-Techne | Catalog # 3747

COA / SDS

Histone deacetylase inhibitor

Discontinued Product

3747 has been discontinued. View all Class I Histone Deacetylases Inhibitors products.

Key Product Details

Description:	Histone deacetylase inhibitor
Alternative Names:	PTACH
Chemical Name:	2-Methylpropanethioic acid S-[7-oxo-7-[(4-phenyl-2-thiazolyl)amino]heptyl] ester
Purity:	≥98% (HPLC)
Molecular Weight:	390.56

View Full Technical Details for NCH 51

Technical Data
Citations

Biological Activity for NCH 51

NCH 51 is a histone deacetylase (HDAC) inhibitor. Inhibits growth of various cancer cells in vitro (EC₅₀ = 1.1 - 9.1 μM).

Technical Data for NCH 51

M. Wt	390.56
Formula	C₂₀H₂₆N₂O₂S₂
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	848354-66-5
PubChem ID	11395181
InChi Key	MDYDGUOQFUQOGE-UHFFFAOYSA-N
Smiles	O=C(CCCCCCSC(C(C)C)=O)NC1=NC(C2=CC=CC=C2)=CS1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for NCH 51

References are publications that support the biological activity of the product.

Sanda Proteome analyses of the growth inhibitory effects of NCH-51, a novel histone deacetylase inhibitor, on lymphoid malignant cells. Leukemia 2007 PMID: 17690692
Suzuki Novel inhibitors of human histone deacetylases: design, synthesis, enzyme inhibition, and cancer cell growth inhibition of SAHA-based non-hydroxamates. J.Med.Chem. 2005 PMID: 15715470

NCH 51

Tocris Bioscience, part of Bio-Techne | Catalog # 3747

Key Product Details

Biological Activity for NCH 51

Technical Data for NCH 51

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for NCH 51

Product Documents for NCH 51

COA

Certificate of Analysis

SDS

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