Phen Green SK diacetate
Tocris Bioscience, part of Bio-Techne | Catalog # 7873
Heavy metal ion indicator, membrane permeable
Key Product Details
Description
Heavy metal ion indicator, membrane permeable
Product Description
Phen Green SK diacetate is a fluorescent heavy metal ion indicator that can be used to detect various metal ions including Cu2+, Cu+, Fe2+, Hg2+, Pb2+, Cd2+, Zn2+ and Ni2+. Excitation and emission maxima (λ) are 507 and 532 nm, respectively. Intracellular Phen Green SK diacetate fluorescence is quenched upon reaction with metal ions. This product is cell permeable.It is recommended to prepare stock solutions in DMSO.
Optical Data
| λabs | 507 nm |
| λem | 532 nm |
| Extinction Coefficient (ε) | 40000 M-1cm-1 |
| Cell Permeable | Yes |
| Application | Fluorescence Microscopy, Flow Cytometry |
Spectra Viewer
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Spectra ViewerProduct Specifications
Molecular Weight
706.49
Formula
C37H21Cl2N3O8
Storage
Store at -20°C
Purity
≥90% (HPLC)
Chemical Name
3',6'-Bis(acetyloxy)-2',7'-dichloro-3-oxo-N-1,10-phenanthrolin-5-yl-spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-5-carboxamide
CAS Number
234075-45-7
PubChem ID
137700453
InChI Key
INOXUAMBIQQWOK-UHFFFAOYSA-N
SMILES
O=C1OC2(C3=CC=C(C(NC4=CC5=CC=CN=C5C6=C4C=CC=N6)=O)C=C13)C7=CC(Cl)=C(C=C7OC8=CC(OC(C)=O)=C(C=C82)Cl)OC(C)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Background References
References are publications that support the biological activity of the product.
- Kim Calibration of Phen Green for use as a Cu(I)-selective fluorescent indicator. Anal.Chim.Acta 2006 PMID: 17723595
- Lu Epigenetic regulation of ferroptosis via ETS1/miR-23a-3p/ACSL4 axis mediates sorafenib resistance in human hepatocellular carcinoma. J.Exp.Clin.Cancer Res. 2022 PMID: 34980204
- Shen Geniposide possesses the protective effect on myocardial injury by inhibiting oxidative stress and ferroptosis via activation of the Grsf1/GPx4 Axis. Front.Pharmacol. 2022 PMID: 35600863
Product Specific Notices for Phen Green SK diacetate
For research use only
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