FFN 206 dihydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 5043
Fluorescent VMAT2 substrate
Key Product Details
Description
Fluorescent VMAT2 substrate
Product Description
FFN 206 dihydrochloride is a fluorescent VMAT2 substrate (IC50 app = 1.15 μM). Allows detection of VMAT2 subcellular locations in cell culture. Exhibits no detectable inhibition of DAT. Excitation maximum = 369 nm; emission maximum = 464 nm.Licensing Information
Sold with the permission of Columbia UniversityOptical Data
| Emission Color | Blue |
| λabs | 369 nm |
| λem | 464 nm |
| Application | Fluorescence Microscopy, Confocal Microscopy |
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Product Specifications
Molecular Weight
291.17
Formula
C12H14N2O2.2HCl
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
4-(2-Aminoethyl)-7-(methylamino)-2H-1-benzopyran-2-one dihydrochloride
CAS Number
1883548-88-6
PubChem ID
91826079
InChI Key
ODENAPXTSFPACZ-UHFFFAOYSA-N
SMILES
CNC1=CC=C2C(OC(C=C2CCN)=O)=C1.Cl.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 29.12 | 100 | |
| DMSO | 14.56 | 50 |
Preparing Stock Solutions
for FFN 206 dihydrochloride
The following data is based on the product molecular weight 291.17
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.43 mL | 17.17 mL | 34.34 mL |
| 5 mM | 0.69 mL | 3.43 mL | 6.87 mL |
| 10 mM | 0.34 mL | 1.72 mL | 3.43 mL |
| 50 mM | 0.07 mL | 0.34 mL | 0.69 mL |
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Background References
References are publications that support the biological activity of the product.
- Hu New fluorescent substrate enables quantitative and high-throughput examination of vesicular monoamine transporter 2 (VMAT2). ACS Chem.Biol. 2013 PMID: 23859623
Product Specific Notices for FFN 206 dihydrochloride
For research use only
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