6 TMR Tre
Tocris Bioscience, part of Bio-Techne | Catalog # 6802
Fluorescent trehalose; selectively labels mycobacterial cell envelope
Key Product Details
Description
Fluorescent trehalose; selectively labels mycobacterial cell envelope
Product Description
6 TMR Tre is a fluorescent trehalose conjugate for imaging bacterial cell envelope. Selectively labels mycobacterial trehalose monomycolate (TMM). Allows real-time visualization of peptidoglycan and monomycolate dynamics at the single-cell level. Suitable for use with confocal and super-resolution microscopy.Optical Data
| Emission Color | Yellow |
| λabs | 532 nm |
| λem | 580 nm |
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Product Specifications
Molecular Weight
753.75
Formula
C37H43N3O14
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
6-[4(3)-[3,6-bis(dimethylamino)xanthylium-9-yl]-3(4)-carboxybenzoyl]amino-6-deoxy-α,α-D-trehalose
SMILES
[H][C@]1([C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1)O[C@@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CNC(C3=CC(C([O-])=O)=C(C4=C(C=C/5)C(OC6=C4C=CC(N(C)C)=C6)=CC5=[N+](C)/C)C=C3)=O)O2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 5 |
Preparing Stock Solutions
for 6 TMR Tre
The following data is based on the product molecular weight 753.75
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.07 mM | 18.95 mL | 94.76 mL | 189.53 mL |
| 0.35 mM | 3.79 mL | 18.95 mL | 37.91 mL |
| 0.7 mM | 1.90 mL | 9.48 mL | 18.95 mL |
| 3.5 mM | 0.38 mL | 1.90 mL | 3.79 mL |
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Background References
References are publications that support the biological activity of the product.
- Rodriguez-Rivera Acute modulation of mycobacterial cell envelope biogenesis by front-line tuberculosis drugs. Angew.Chem.Int.Ed. 2018 PMID: 29392891
Product Specific Notices for 6 TMR Tre
For research use only
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