Quantikine Immunoassay Control Set 1149 for Human Hepcidin

R&D Systems, part of Bio-Techne | Catalog # QC220

For use with catalog number DHP250
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Key Product Details

Species

Human

Applications

Control

Formulation, Preparation, and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: Hepcidin

The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure.

Long Name

Hepcidin Antimicrobial Peptide

Alternate Names

HAMP, HEPC, HFE2B, LEAP1, PLTR

Entrez Gene IDs

57817 (Human); 84506 (Mouse); 84604 (Rat)

Gene Symbol

HAMP

Additional Hepcidin Products

Product Documents for Quantikine Immunoassay Control Set 1149 for Human Hepcidin

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Quantikine Immunoassay Control Set 1149 for Human Hepcidin

For research use only

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