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Prostaglandin E2 Parameter Assay Kit
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$35 to United States
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Key Product Details
| Assay Length: | 3.5 hours |
| Sample Type & Volume Required Per Well: | Cell Culture Supernates (51 uL), Serum (51 uL), EDTA Plasma (51 uL), Heparin Plasma (51 uL), Urine (51 uL) |
| Sample Types: | Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Urine |
| Sensitivity: | 41.4 pg/mL |
| Assay Range: | 39 - 2,500 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
| Prostaglandin E2 Parameter Assay Kit Summary: | The Parameter PGE2 Immunoassay is a 3.5 hour forward sequential competitive enzyme immunoassay designed to measure PGE2 in cell culture supernates, serum, plasma, and urine. |
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Multi-species Prostaglandin E2/PGE2 ELISA Standard Curve |
Citations for Prostaglandin E2 Parameter Assay Kit (310)
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Citations are publications that use Bio-Techne products. Selected citations for Prostaglandin E2 Parameter Assay Kit include:
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Species: Mouse
Sample Types: Cell Culture Supernates
Z Zhou et al. (2022), Luteolin Protects Chondrocytes from H2O2-Induced Oxidative Injury and Attenuates Osteoarthritis Progression by Activating AMPK-Nrf2 Signaling Oxidative Medicine and Cellular Longevity, 2022(0):5635797.
PMID: 35154568 -
Species: Rat
Sample Types: Cell Lysates
X Hu et al. (2022), Protectin DX promotes the inflammatory resolution via activating COX-2/L-PGDS-PGD2 and DP1 receptor in acute respiratory distress syndrome International immunopharmacology, 102(0):108348.
PMID: 34920958 -
Species: Human
Sample Types: Cell Culture Supernates
JH Cai et al. (2022), HucMSCs-exosomes containing miR-21 promoted estrogen production in ovarian granulosa cells via LATS1-mediated phosphorylation of LOXL2 and YAP General and comparative endocrinology, 0(0):114015.
PMID: 35271888 -
Species: Rat
Sample Types: Serum
X Gao et al. (2022), Piceatannol suppresses inflammation and promotes apoptosis in rheumatoid arthritis?fibroblast?like synoviocytes by inhibiting the NF?kappaB and MAPK signaling pathways Molecular Medicine Reports, 25(5).
PMID: 35322865 -
Species: Mouse
Sample Types: Cell Culture Supernates
Y Yuan et al. (2022), Dehydrocostus Lactone Suppresses Dextran Sulfate Sodium-Induced Colitis by Targeting the IKKalpha/beta-NF-kappaB and Keap1-Nrf2 Signalling Pathways Frontiers in Pharmacology, 13(0):817596.
PMID: 35321327 -
Species: Rat
Sample Types: Plasma
J Hernandez- et al. (2022), Imbalances in TCA, Short Fatty Acids and One-Carbon Metabolisms as Important Features of Homeostatic Disruption Evidenced by a Multi-Omics Integrative Approach of LPS-Induced Chronic Inflammation in Male Wistar Rats International Journal of Molecular Sciences, 23(5).
PMID: 35269702 -
Species: Human
Sample Types: Cell Culture Supernates
E Kuca-Warna et al. (2021), Impact and Possible Mechanism(s) of Adipose Tissue-Derived Mesenchymal Stem Cells on T-Cell Proliferation in Patients With Rheumatic Disease Frontiers in Physiology, 12(0):749481.
PMID: 35095547 -
Species: Mouse
Sample Types: Cell Culture Supernates
HJ Kim et al. (2021), Berberine modulates hyper-inflammation in mouse macrophages stimulated with polyinosinic-polycytidylic acid via calcium-CHOP/STAT pathway Scientific Reports, 11(1):11298.
PMID: 34050236 -
Species: Human
Sample Types: Cell Lysates
H Mohammadpo et al. (2021), beta2-adrenergic receptor signaling regulates metabolic pathways critical to myeloid-derived suppressor cell function within the TME Cell Reports, 37(4):109883.
PMID: 34706232 -
Species: Mouse
Sample Types: Tissue Homogenates
JJ Shi et al. (2021), Danggui-Shaoyao-San improves cognitive impairment through inhibiting O-GlcNAc-modification of estrogen alpha receptor in female db/db mice Journal of ethnopharmacology, 281(0):114562.
PMID: 34438027 -
Species: Human
Sample Types: Cell Culture Supernates
R Jeske et al. (2021), Agitation in a Microcarrier-based Spinner Flask Bioreactor Modulates Homeostasis of Human Mesenchymal Stem Cells Biochemical engineering journal, 168(0).
PMID: 33967591 -
Species: Mouse
Sample Types: Cell Culture Supernates
JJ Tang et al. (2021), 1,10-Seco-Eudesmane sesquiterpenoids as a new type of anti-neuroinflammatory agents by suppressing TLR4/NF-kappaB/MAPK pathways European Journal of Medicinal Chemistry, 224(0):113713.
PMID: 34315042 -
Species: Mouse
Sample Types: Cell Culture Supernates
H Lee et al. (2021), Anti-Neuroinflammatory and Anti-Inflammatory Activities of Phenylheptatriyne Isolated from the Flowers of Coreopsis lanceolata L. via NF-kappaB Inhibition and HO-1 Expression in BV2 and RAW264.7 Cells International Journal of Molecular Sciences, 22(14).
PMID: 34299102 -
Species: Human
Sample Types: Cell Culture Supernates
I Pountos et al. (2021), NSAIDs inhibit bone healing through the downregulation of TGF-&beta3 expression during endochondral ossification Injury, 0(0).
PMID: 33472741 -
Species: Human
Sample Types: Cell Culture Supernates
YK Ji et al. (2021), Stereochemical Determination of Fistularins Isolated from the Marine Sponge Ecionemia acervus and Their Regulatory Effect on Intestinal Inflammation Marine Drugs, 19(3).
PMID: 33809895 -
Species: Human
Sample Types: Cell Culture Supernates
N Jones et al. (2021), Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation Nature Communications, 12(1):1209.
PMID: 33619282 -
Species: Mouse
Sample Types: Cell Culture Supernates
BO Cho et al. (2021), Anti?inflammatory effect of Chrysanthemum zawadskii, peppermint, Glycyrrhiza glabra herbal mixture in�lipopolysaccharide?stimulated RAW264.7 macrophages Molecular Medicine Reports, 24(1).
PMID: 34036392 -
Species: Equine
Sample Types: Synovial Fluid
L Bertoni et al. (2021), Evaluation of Allogeneic Bone-Marrow-Derived and Umbilical Cord Blood-Derived Mesenchymal Stem Cells to Prevent the Development of Osteoarthritis in An Equine Model International Journal of Molecular Sciences, 22(5).
PMID: 33801461 -
Species: Rat
Sample Types: Serum
GY Min et al. (2021), Inhibition effect of Caragana sinica root extracts on Osteoarthritis through MAPKs, NF-&kappaB signaling pathway International Journal of Medical Sciences, 18(4):861-872.
PMID: 33456343 -
Species: Human
Sample Types: Cell Culture Supernates
YN Kim et al. (2021), Isoquinolinequinone Derivatives from a Marine Sponge (Haliclona sp.) Regulate Inflammation in In Vitro System of Intestine Marine Drugs, 19(2).
PMID: 33557170 -
Species: Human
Sample Types: Cell Culture Supernates
C Park et al. (2021), Inhibition of Lipopolysaccharide-Induced Inflammatory and Oxidative Responses by Trans-cinnamaldehyde in C2C12 Myoblasts International Journal of Medical Sciences, 18(12):2480-2492.
PMID: 34104079 -
Species: Human
Sample Types: Cell Culture Supernates
P Filannino et al. (2021), Nutrients Bioaccessibility and Anti-inflammatory Features of Fermented Bee Pollen: A Comprehensive Investigation Frontiers in Microbiology, 12(0):622091.
PMID: 33603725 -
Species: Mouse
Sample Types: Cell Culture Supernates
E Park et al. (2021), Antiosteoarthritic Effect of Morroniside in Chondrocyte Inflammation and Destabilization of Medial Meniscus-Induced Mouse Model International Journal of Molecular Sciences, 22(6).
PMID: 33804203 -
Species: Human
Sample Types: Plasma
R Xing et al. (2021), Extracorporeal shock wave therapy for treating primary dysmenorrhea: A randomized controlled trial Medicine, 100(5):e23798.
PMID: 33592837 -
Species: Human
Sample Types: Cell Culture Supernates
S Gonçalves et al. (2021), COX2 regulates senescence secretome composition and senescence surveillance through PGE2 Cell Reports, 34(11):108860.
PMID: 33730589 -
Species: Human
Sample Types: Cell Culture Supernates
Y Yan et al. (2021), Cyclic mechanical stimulation inhibits rheumatoid arthritis fibroblast-like synoviocytes proliferation via cell cycle arrest Journal of biomechanics, 121(0):110424.
PMID: 33873113 -
Species: Mouse
Sample Types: Cell Culture Supernates
L Dai et al. (2021), Elevated beta-secretase 1 expression mediates CD4+ T cell dysfunction via PGE2 signalling in Alzheimer's disease Brain, Behavior, and Immunity, 98(0):337-348.
PMID: 34500034 -
Species: Human
Sample Types: Sputum Supernates
J Cheng et al. (2021), Cough hypersensitivity in patients with metabolic syndrome: a clinical finding and its possible mechanisms BMC pulmonary medicine, 21(1):284.
PMID: 34488706 -
Species: Human
Sample Types: Cell Culture Supernates
CH Lee et al. (2021), High-Molecular-Weight Hyaluronic Acid Inhibits IL-1beta-Induced Synovial Inflammation and Macrophage Polarization through the GRP78-NF-kappaB Signaling Pathway International Journal of Molecular Sciences, 22(21).
PMID: 34769349 -
Species: Rat
Sample Types: Cell Culture Supernates
CY Chang et al. (2021), DHA attenuated Japanese Encephalitis virus infection-induced neuroinflammation and neuronal cell death in cultured rat Neuron/glia Brain, Behavior, and Immunity, 0(0).
PMID: 33486004 -
Species: Camel
Sample Types: Serum
RH Mohamed et al. (2021), Clinical and Correlated Responses among Steroid Hormones and Oxidant/Antioxidant Biomarkers in Pregnant, Non-Pregnant and Lactating CIDR-Pre-Synchronized Dromedaries (Camelus dromedarius) Veterinary sciences, 8(11).
PMID: 34822620 -
Species: Mouse
Sample Types: Cell Culture Supernates
KM Kim et al. (2021), Dracocephalum moldavica Ethanol Extract Suppresses LPS-Induced Inflammatory Responses through Inhibition of the JNK/ERK/NF-kappaB Signaling Pathway and IL-6 Production in RAW 264.7 Macrophages and in Endotoxic-Treated Mice Nutrients, 13(12).
PMID: 34960054 -
Species: Human
Sample Types: Cell Culture Supernates
A Stemmler et al. (2021), GDF15 Supports the Inflammatory Response of PdL Fibroblasts Stimulated by P. gingivalis LPS and Concurrent Compression International Journal of Molecular Sciences, 22(24).
PMID: 34948405 -
Species: Human
Sample Types: Cell Culture Supernates
MR Shin et al. (2021), Immunomodulatory and anti-inflammatory effects of Phellinus linteus mycelium BMC complementary medicine and therapies, 21(1):269.
PMID: 34702240 -
Species: Human
Sample Types: Cell Culture Supernates
Y Wang et al. (2021), CCNB2/SASP/Cathepsin B & PGE2 Axis Induce Cell Senescence Mediated Malignant Transformation International journal of biological sciences, 17(13):3538-3553.
PMID: 34512164 -
Species: Mouse
Sample Types: Tissue Homogenates
S Liu et al. (2021), TRPV1 Channel Activated by the PGE2/EP4 Pathway Mediates Spinal Hypersensitivity in a Mouse Model of Vertebral Endplate Degeneration Oxidative Medicine and Cellular Longevity, 2021(0):9965737.
PMID: 34471470 -
Species: Human
Sample Types: Cell Culture Supernates
SW Shin et al. (2021), Anti-Periodontitis Effect of Ethanol Extracts of Alpinia Katsumadai Seeds Nutrients, 14(1).
PMID: 35011011 -
Species: Human
Sample Types: Cell Culture Supernates
Y Zhao et al. (2020), Berberine Inhibits the Apoptosis-Induced Metastasis by Suppressing the iPLA2/LOX-5/LTB4 Pathway in Hepatocellular Carcinoma Onco Targets Ther, 13(0):5223-5230.
PMID: 32606742 -
Species: Mouse
Sample Types: Cell Culture Supernates
T Park et al. (2020), 7-Acetoxycoumarin Inhibits LPS-Induced Inflammatory Cytokine Synthesis by I&kappaB&alpha Degradation and MAPK Activation in Macrophage Cells Molecules, 25(14).
PMID: 32650550 -
Species: Mouse
Sample Types: Cell Culture Supernates
ES Son et al. (2020), Anti?inflammatory activity of 3,5,6,7,3',4'?hexamethoxyflavone via repression of the NF?&kappaB and MAPK signaling pathways in LPS?stimulated RAW264.7 cells Mol Med Rep, 22(3):1985-1993.
PMID: 32705181 -
Species: Human
Sample Types: Plasma
EV Sokolova et al. (2020), Effect of carrageenans on some lipid metabolism components in vitro Carbohydr Polym, 230(0):115629.
PMID: 31887898 -
Species: Human
Sample Types: Cell Culture Supernates
S Queckbörne et al. (2020), Endometrial stromal cells exhibit a distinct phenotypic and immunomodulatory profile Stem Cell Res Ther, 11(1):15.
PMID: 31907034 -
Species: Mouse
Sample Types: Tissue Homogenate
L Yang et al. (2020), Induction of DNMT3B by PGE2 and IL6 at distant metastatic sites promotes epigenetic modification and breast cancer colonization Cancer Res., 0(0).
PMID: 32265226 -
Species: Human
Sample Types: Cell Culture Supernates
F Nishimura et al. (2020), Mechanisms of thrombin-Induced myometrial contractions: Potential targets of progesterone PLoS ONE, 15(5):e0231944.
PMID: 32365105 -
Species: Human
Sample Types: Cell Culture Supernates
HJ Lee et al. (2020), Mesenchymal stromal cells induce distinct myeloid-derived suppressor cells in inflammation JCI Insight, 0(0).
PMID: 32453713 -
Species: Human
Sample Types: Cell Culture Supernates
HH Park et al. (2020), TGF-&beta secreted by human umbilical cord blood-derived mesenchymal stem cells ameliorates atopic dermatitis by inhibiting secretion of TNF-&alpha and IgE Stem Cells, 0(0).
PMID: 32277785 -
Species: Mouse
Sample Types: Tissue Homoegenates
JA Lopes et al. (2020), Machaerium hirtum (Vell.) Stellfeld Alleviates Acute Pain and Inflammation: Potential Mechanisms of Action Biomolecules, 10(4).
PMID: 32290371 -
Species: Fungus
Sample Types: Fungal Extract
TM Ha et al. (2020), Anti-Inflammatory and Protein Tyrosine Phosphatase 1B Inhibitory Metabolites from the Antarctic Marine-Derived Fungal Strain Penicillium glabrum SF-7123 Mar Drugs, 18(5).
PMID: 32397523 -
Species: Human
Sample Types: Cell Culture Supernates
KS Lee et al. (2020), Inhibition of UVB-Induced Inflammation by Laminaria japonica Extract via Regulation of nc886-PKR Pathway Nutrients, 12(7).
PMID: 32630038 -
Species: Mouse
Sample Types: Cell Culture Supernatants
M Lo Monaco et al. (2020), Therapeutic Potential of Dental Pulp Stem Cells and Leukocyte- and Platelet-Rich Fibrin for Osteoarthritis Cells, 9(4).
PMID: 32326610 -
Species: Human
Sample Types: Conditioned Media
C Behm et al. (2020), Cytokines Differently Define the Immunomodulation of Mesenchymal Stem Cells from the Periodontal Ligament Cells, 9(5).
PMID: 32423044 -
Species: Mouse
Sample Types: Cell Culture Supernates
T Wongwat et al. (2020), Suppression of inflammatory mediators and matrix metalloproteinase (MMP)-13 by Morus alba stem extract and oxyresveratrol in RAW 264.7?cells and C28/I2 human chondrocytes J Tradit Complement Med, 10(2):132-140.
PMID: 32257876 -
Species: Mouse
Sample Types: Cell Culture Supernates
BO Cho et al. (2020), In vitro Anti-Inflammatory and Anti-Oxidative Stress Activities of Kushenol C Isolated from the Roots of Sophoraflavescens Molecules, 25(8).
PMID: 32290603 -
Species: Mouse
Sample Types: Aqueous Humor
Y Zhao et al. (2020), I-alowCD11bhigh DC Regulates the Immune Response in the Eyes of Experimental Autoimmune Uveitis Mediators Inflamm., 2020(0):6947482.
PMID: 32256194 -
Species: Rat
Sample Types: Tissue Homogenates
CG Kim et al. (2020), Effects of Balneotherapy in Jeju Magma-Seawater on Knee Osteoarthritis Model Sci Rep, 10(1):6620.
PMID: 32313003 -
Species: Mouse
Sample Types: BALF
M Hecker et al. (2020), Immunomodulation by an Omega-6 Fatty Acid Reduced Mixed Lipid Emulsion in Murine Acute Respiratory Distress Syndrome J Clin Med, 9(7).
PMID: 32610690 -
Species: Human
Sample Types: Supernatant
E Saadi et al. (2020), Limited Proteolysis of Cyclooxygenase-2 Enhances Cell Proliferation Int J Mol Sci, 21(9).
PMID: 32366045 -
Species: Mouse
Sample Types: Cell Culture Supernates
Y Li et al. (2020), Fucoxanthinol from the Diatom Nitzschia Laevis Ameliorates Neuroinflammatory Responses in Lipopolysaccharide-Stimulated BV-2 Microglia Mar Drugs, 18(2).
PMID: 32079242 -
Species: Mouse
Sample Types: Cell Culture Supernates
NF Guo et al. (2020), Prostaglandin E2 receptor subtypes 1 and 2 play a role in TGF-beta1-induced renal fibrosis by regulating endoplasmic reticulum stress Eur Rev Med Pharmacol Sci, 24(9):4954-4962.
PMID: 32432758 -
Species: Human
Sample Types: Cell Culture Supernates
A Allen et al. (2020), Mesenchymal Stromal Cell Bioreactor for Ex Vivo Reprogramming of Human Immune Cells Sci Rep, 10(1):10142.
PMID: 32576889 -
Species: Tinospora crispa
Sample Types: Cell Culture Supernates
MA Haque et al. (2020), Standardized ethanol extract of Tinospora crispa upregulates pro-inflammatory mediators release in LPS-primed U937 human macrophages through stimulation of MAPK, NF-&kappaB and PI3K-Akt signaling networks BMC Complement Med Ther, 20(1):245.
PMID: 32762741 -
Species: Equine
Sample Types: Synovial Fluid
L Bertoni et al. (2020), An experimentally induced osteoarthritis model in horses performed on both metacarpophalangeal and metatarsophalangeal joints: Technical, clinical, imaging, biochemical, macroscopic and microscopic characterization PLoS ONE, 15(6):e0235251.
PMID: 32584901 -
Species: Human
Sample Types: Cell Culture Supernates
P Zhu et al. (2020), 3,3'-Diindolylmethane modulates aryl hydrocarbon receptor of esophageal squamous cell carcinoma to reverse epithelial-mesenchymal transition through repressing RhoA/ROCK1-mediated COX2/PGE2 pathway J. Exp. Clin. Cancer Res., 39(1):113.
PMID: 32546278 -
Species: Human
Sample Types: Cell Culture Supernates
S Di Blasio et al. (2020), The tumour microenvironment shapes dendritic cell plasticity in a human organotypic melanoma culture Nat Commun, 11(1):2749.
PMID: 32488012 -
Species: Mouse
Sample Types: Cell Culture Supernates
K Lynch et al. (2020), TGF-beta1-Licensed Murine MSCs Show Superior Therapeutic Efficacy in Modulating Corneal Allograft Immune Rejection In�Vivo Mol. Ther., 0(0).
PMID: 32531237 -
Species: Mouse
Sample Types: Cell Culture Supernates
Y Wu et al. (2020), Salvianolic Acid A Has Anti-Osteoarthritis Effect In Vitro and In Vivo Front Pharmacol, 11(0):682.
PMID: 32581777 -
Species: Human
Sample Types: Cell Culture Supernates
Applications: BioassayC Salgado et al. (2020), Nano wet milled celecoxib extended release microparticles for local management of chronic inflammation Int J Pharm, 589(0):119783.
PMID: 32827674 -
Species: Rat
Sample Types: Cell Culture Supernates
L Jia et al. (2020), Anticolitic Effect of Berberine in Rat Experimental Model: Impact of PGE2/p38 MAPK Pathways Mediators Inflamm, 2020(0):9419085.
PMID: 33061833 -
Species: Mouse
Sample Types: Cell Culture Supernates
MFA Mohamed et al. (2020), Design, synthesis and molecular modeling of novel aryl carboximidamides and 3-aryl-1,2,4-oxadiazoles derived from indomethacin as potent anti-inflammatory iNOS/PGE2 inhibitors Bioorg Chem, 105(0):104439.
PMID: 33161252 -
Species: Mouse
Sample Types: Cell Culture Supernates
H Liu et al. (2020), Upregulation of Cytokines and Differentiation of Th17 and Treg by Dendritic Cells: Central Role of Prostaglandin E2 Induced by Mycobacterium bovis Microorganisms, 8(2).
PMID: 32023904 -
Species: Rat
Sample Types: Tissue Homogenates
X Zhao et al. (2019), Treatment Effects of Jinlingzi Powder and Its Extractive Components on Gastric Ulcer Induced by Acetic Acid in Rats Evid Based Complement Alternat Med, 2019(0):7365841.
PMID: 30719066 -
Species: Mouse
Sample Types: Cell Culture Supernates
N Van Thanh et al. (2019), Chemical constituents from Vietnamese mangrove Calophyllum inophyllum and their anti-inflammatory effects Bioorg. Chem., 88(0):102921.
PMID: 30991191 -
Species: Human
Sample Types: Cell Culture Supernates
SM Lee et al. (2019), (10Z)-Debromohymenialdisine from Marine Sponge Stylissa sp. Regulates Intestinal Inflammatory Responses in Co-Culture Model of Epithelial Caco-2 Cells and THP-1 Macrophage Cells Molecules, 24(18).
PMID: 31540496 -
Species: Porcine
Sample Types: Tissue Culture Supernates
W Pearson et al. (2019), A biological extract of turmeric (Curcuma longa) modulates response of cartilage explants to lipopolysaccharide BMC Complement Altern Med, 19(1):252.
PMID: 31506082 -
Species: Rat
Sample Types: Serum
YM Woo et al. (2019), Anti-inflammatory effects of the combined extracts of Achyranthes japonica nakai and Aralia continentalis kitagawa in�vitro and in�vivo Data Brief, 25(0):104088.
PMID: 31294054 -
Species: Human
Sample Types: Cell Culture Supernates
Y Shibaike et al. (2019), 2-Carba cyclic phosphatidic acid inhibits lipopolysaccharide-induced prostaglandin E2 production in a human macrophage cell line Biochem Biophys Rep, 19(0):100668.
PMID: 31367683 -
Species: Human
Sample Types: Cell Culture Supernates
CH Yu et al. (2019), Inhibitory Effects of a Novel Chrysin-Derivative, CPD 6, on Acute and Chronic Skin Inflammation Int J Mol Sci, 20(11).
PMID: 31141897 -
Species: Human
Sample Types: Cell Culture Supernates
L Song et al. (2019), Assembly of Human Stem Cell-Derived Cortical Spheroids and Vascular Spheroids to Model 3-D Brain-like Tissues Sci Rep, 9(1):5977.
PMID: 30979929 -
Species: Mouse
Sample Types: Cell Culture Supernates
YG Lee et al. (2019), 6-Methoxyflavonols from the aerial parts of Tetragonia tetragonoides (Pall.) Kuntze and their anti-inflammatory activity Bioorg. Chem., 88(0):102922.
PMID: 31003077 -
Species: Human
Sample Types: Cell Culture Supernates
D Zhu et al. (2019), Downregulation of Aquaporin 3 Mediated the Laxative Effect in the Rat Colon by a Purified Resin Glycoside Fraction from Pharbitis Semen Evid Based Complement Alternat Med, 2019(0):9406342.
PMID: 30733814 -
Species: Rat
Sample Types: Serum
XY Jia et al. (2019), CP-25 reverses prostaglandin E4 receptor desensitization-induced fibroblast-like synoviocyte dysfunction via the G protein-coupled receptor kinase 2 in autoimmune arthritis Acta Pharmacol. Sin., 0(0).
PMID: 30643209 -
Species: Rat
Sample Types: Serum
N Kangwan et al. (2019), Rosmarinic Acid Enriched Fraction from Perilla frutescens Leaves Strongly Protects Indomethacin-Induced Gastric Ulcer in Rats Biomed Res Int, 2019(0):9514703.
PMID: 30949513 -
Species: Human
Sample Types: Cell Culture Supernates
V Miceli et al. (2019), Comparison of Immunosuppressive and Angiogenic Properties of Human Amnion-Derived Mesenchymal Stem Cells between 2D and 3D Culture Systems Stem Cells Int, 2019(0):7486279.
PMID: 30911299 -
Species: Rat
Sample Types: Serum
YM Woo et al. (2019), Anti-inflammatory effects of the combined extracts of Achyranthes japonica nakai and Aralia continentalis kitagawa in�vitro and in�vivo Data Brief, 25(0):104088.
PMID: 31294054 -
Species: Mouse
Sample Types: Cell Culture Supernates
XJ Li et al. (2019), Chemical Constituents and an Antineuroinflammatory Lignan, Savinin from the Roots of Acanthopanax henryi Evid Based Complement Alternat Med, 2019(0):1856294.
PMID: 30915141 -
YY Dai et al. (2019), Stem cells from human exfoliated deciduous teeth correct the immune imbalance of allergic rhinitis via Treg cells in vivo and in vitro Stem Cell Res Ther, 10(1):39.
PMID: 30670101 -
Species: Human
Sample Types: Tissue Homogenates
X Li et al. (2019), The protective effect of sinapic acid in osteoarthritis: In vitro and in vivo studies J. Cell. Mol. Med., 0(0).
PMID: 30604480 -
Species: Human
Sample Types: Cell Culture Supernates
A Islam et al. (2019), Large-scale secretome analyses unveil the superior immunosuppressive phenotype of umbilical cord stromal cells as compared to other adult mesenchymal stromal cells Eur Cell Mater, 37(0):153-174.
PMID: 30785213 -
Species: Mouse
Sample Types: Cell Culture Supernates
H Jeon et al. (2019), Anti-Arthritis Effect through the Anti-Inflammatory Effect of Sargassum muticum Extract in Collagen-Induced Arthritic (CIA) Mice Molecules, 24(2).
PMID: 30642121 -
Species: Human
Sample Types: Spheroid
TJ Bartosh et al. (2019), Efficacy of 3D Culture Priming is Maintained in Human Mesenchymal Stem Cells after Extensive Expansion of the Cells Cells, 8(9).
PMID: 31491901 -
Species: Human
Sample Types: Whole Tissue
Applications: BioassayDW Barrett et al. (2019), Targeting mechanotransduction mechanisms and tissue weakening signals in the human amniotic membrane Sci Rep, 9(1):6718.
PMID: 31040291 -
Species: Human
Sample Types: Serum
M Vijarnsorn et al. (2019), The effectiveness of marine based fatty acid compound (PCSO-524) and firocoxib in the treatment of canine osteoarthritis BMC Vet. Res., 15(1):349.
PMID: 31623621 -
Species: Mouse
Sample Types: Serum
B Sun et al. (2019), miR-644-5p carried by bone mesenchymal stem cell-derived exosomes targets regulation of p53 to inhibit ovarian granulosa cell apoptosis Stem Cell Res Ther, 10(1):360.
PMID: 31783913 -
Species: Human
Sample Types: Cell Culture Supernates
D Chen et al. (2019), Pharmacological blockade of PCAF ameliorates osteoarthritis development via dual inhibition of TNF-alpha-driven inflammation and ER stress EBioMedicine, 0(0).
PMID: 31735552 -
Species: Human
Sample Types: Cell Culture Supernates
E Kuca-Warna et al. (2019), The Phenotype and Secretory Activity of Adipose-Derived Mesenchymal Stem Cells (ASCs) of Patients with Rheumatic Diseases Cells, 8(12).
PMID: 31861245 -
Species: Human
Sample Types: Cell Culture Supernates
? Uram et al. (2019), The Effect of Biotinylated PAMAM G3 Dendrimers Conjugated with COX-2 Inhibitor (celecoxib) and PPARgammaAgonist (Fmoc-L-Leucine) on Human Normal Fibroblasts, Immortalized Keratinocytes and Glioma Cells in Vitro Molecules, 24(20).
PMID: 31652556 -
Species: Equine
Sample Types: Synovial Fluid
L Bertoni et al. (2019), Intra-Articular Injection of 2 Different Dosages of Autologous and Allogeneic Bone Marrow- and Umbilical Cord-Derived Mesenchymal Stem Cells Triggers a Variable Inflammatory Response of the Fetlock Joint on 12 Sound Experimental Horses Stem Cells Int, 2019(0):9431894.
PMID: 31191689 -
Species: Mouse
Sample Types: Tissue Lysate
S Ni et al. (2019), Sensory innervation in porous endplates by Netrin-1 from osteoclasts mediates PGE2-induced spinal hypersensitivity in mice Nat Commun, 10(1):5643.
PMID: 31822662 -
Species: Rat
Sample Types: Gingival Fluid
JMO Freire et al. (2019), Protective effect of Platymiscium floribundum Vog. in tree extract on periodontitis inflammation in rats PLoS ONE, 14(11):e0223800.
PMID: 31682614 -
Species: Rat
Sample Types: Cell Culture Supernates
P Ma et al. (2019), Chondroprotective and anti-inflammatory effects of amurensin H by regulating TLR4/Syk/NF-kappaB signals J. Cell. Mol. Med., 0(0).
PMID: 31876072 -
Species: Porcine
Sample Types: Cell Culture Supernates
H Cho et al. (2019), Nanosome-Mediated Delivery Of Protein Kinase D Inhibitor Protects Chondrocytes From Interleukin-1beta-Induced Stress And Apoptotic Death Int J Nanomedicine, 14(0):8835-8846.
PMID: 31806974 -
Species: Human
Sample Types: Cell Culture Supernates
S Regmi et al. (2019), Intraportally delivered stem cell spheroids localize in the liver and protect hepatocytes against GalN/LPS-induced fulminant hepatic toxicity Stem Cell Res Ther, 10(1):230.
PMID: 31615539 -
Species: Human
Sample Types: Cell Culture Supernates
SY Kim et al. (2019), Effects of Placenta-Derived Mesenchymal Stem Cells on the Particulate Matter-Induced Damages in Human Middle Ear Epithelial Cells Stem Cells Int, 2019(0):4357684.
PMID: 31814835 -
Species: Human
Sample Types: Cell Culture Supernates
S Rutting et al. (2018), Dietary ?-6 polyunsaturated fatty acid arachidonic acid increases inflammation, but inhibits ECM protein expression in COPD Respir. Res., 19(1):211.
PMID: 30390648 -
Species: Rat
Sample Types: Cell Culture Supernates
WY Chen et al. (2018), Anti-inflammatory and Neuroprotective Effects of Fungal Immunomodulatory Protein Involving Microglial Inhibition Int J Mol Sci, 19(11).
PMID: 30469316 -
Species: Rat
Sample Types: Tissue Homogenates
M Longo et al. (2018), Multiple aPDT sessions on periodontitis in rats treated with chemotherapy: Histomorphometrical, Immunohistochemical, Imunological and Microbiological Analyses Photodiagnosis Photodyn Ther, 0(0).
PMID: 30468900 -
Species: Mouse
Sample Types: Cell Culture Supernates
TH Tseng et al. (2018), Protective Effects of Morus Root Extract (MRE) Against Lipopolysaccharide-Activated RAW264.7 Cells and CCl4-Induced Mouse Hepatic Damage Cell. Physiol. Biochem., 51(3):1376-1388.
PMID: 30481781 -
Species: Mouse
Sample Types: Cell Culture Supernates
AN Won et al. (2018), HO-1 Induction by Selaginella tamariscina Extract Inhibits Inflammatory Response in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages Evid Based Complement Alternat Med, 2018(0):7816923.
PMID: 30581485 -
Species: Mouse
Sample Types: Serum
YS Lee et al. (2018), Inhibition of skin carcinogenesis by suppression of NF-?B dependent ITGAV and TIMP-1 expression in IL-32? overexpressed condition J. Exp. Clin. Cancer Res., 37(1):293.
PMID: 30486830 -
Species: Mouse
Sample Types: Cell Culture Supernates
J Hou et al. (2018), Anti-Inflammatory Effects of Aurantio-Obtusin from Seed of Cassia obtusifolia L. through Modulation of the NF-?B Pathway Molecules, 23(12).
PMID: 30486383 -
Species: Canine
Sample Types: Cell Culture Supernates
LC Dutton et al. (2018), Cardiosphere-derived cells suppress allogeneic lymphocytes by production of PGE2 acting via the EP4 receptor Sci Rep, 8(1):13351.
PMID: 30190508 -
Species: Mouse
Sample Types: Serum
M Li et al. (2018), Lepidiumuridine A: A New Natural Uridine Derivative as a Phytoestrogen Isolated from the Seeds of Lepidium apetalum Willd Evid Based Complement Alternat Med, 2018(0):2813465.
PMID: 30254685 -
Species: Rat
Sample Types: Tissue Homogenates
CT Hsieh et al. (2018), Systemic Lipopolysaccharide-Induced Pain Sensitivity and Spinal Inflammation Were Reduced by Minocycline in Neonatal Rats Int J Mol Sci, 19(10).
PMID: 30262747 -
Species: Mouse
Sample Types: BALF
L Jiang et al. (2018), GYY4137 attenuates LPS-induced acute lung injury via heme oxygenase-1 modulation Pulm Pharmacol Ther, 0(0).
PMID: 30605726 -
Species: Human
Sample Types: Cell Culture Supernates
W Dankers et al. (2018), 1,25(OH)2D3 and dexamethasone additively suppress synovial fibroblast activation by CCR6+ T helper memory cells and enhance the effect of tumor necrosis factor alpha blockade Arthritis Res. Ther., 20(1):212.
PMID: 30236152 -
Species: Mouse
Sample Types: Cell Culture Supernates
CS Yoon et al. (2018), Isolation of Novel Sesquiterpeniods and Anti-neuroinflammatory Metabolites from Nardostachys jatamansi Molecules, 23(9).
PMID: 30227591 -
Species: Human
Sample Types: Plasma
J Zhou et al. (2018), Changes in erythrocyte polyunsaturated fatty acids and plasma eicosanoids level in patients with asthma Lipids Health Dis, 17(1):206.
PMID: 30172255 -
Species: Mouse
Sample Types: Cell Culture Supernates
H Wu et al. (2018), Anti-Inflammatory Effect of a Polyphenol-Enriched Fraction from Acalypha wilkesiana on Lipopolysaccharide-Stimulated RAW 264.7 Macrophages and Acetaminophen-Induced Liver Injury in Mice Oxid Med Cell Longev, 2018(0):7858094.
PMID: 30159118 -
Species: Human
Sample Types: Cell Culture Supernates
X Li et al. (2018), The Protective Effect of Ligustilide in Osteoarthritis: An in Vitro and in Vivo Study Cell. Physiol. Biochem., 48(6):2583-2595.
PMID: 30121673 -
Species: Human
Sample Types: Cell Culture Supernates
JW Park et al. (2018), Effects of Surface Nanotopography and Calcium Chemistry of Titanium Bone Implants on Early Blood Platelet and Macrophage Cell Function Biomed Res Int, 2018(0):1362958.
PMID: 30069461 -
Species: Human
Sample Types: Cell Culture Supernates
Y Li et al. (2018), IL-33 facilitates proliferation of colorectal cancer dependent on�COX2/PGE2 J. Exp. Clin. Cancer Res., 37(1):196.
PMID: 30119635 -
Species: Human
Sample Types: Cell Culture Supernates
JE Millán-Riv et al. (2018), Human Wharton's jelly mesenchymal stem cells protect axotomized rat retinal ganglion cells via secretion of anti-inflammatory and neurotrophic factors Sci Rep, 8(1):16299.
PMID: 30389962 -
Species: Mouse
Sample Types: Cell Culture Supernates
P Silwal et al. (2018), Adenine attenuates lipopolysaccharide-induced inflammatory reactions Korean J. Physiol. Pharmacol., 22(4):379-389.
PMID: 29962852 -
Species: Human
Sample Types: Cell Culture Supernates
R Kalra et al. (2018), AIRE promotes androgen-independent prostate cancer by directly regulating IL-6 and modulating tumor microenvironment Oncogenesis, 7(5):43.
PMID: 29795364 -
Species: Human
Sample Types: Cell Culture Supernates
I Kang et al. (2018), Donor-dependent variation of human umbilical cord blood mesenchymal stem cells in response to hypoxic preconditioning and amelioration of limb ischemia Exp. Mol. Med., 50(4):35.
PMID: 29674661 -
Species: Mouse
Sample Types: Cell Culture Supernates
MH Lee et al. (2018), Antiskin Inflammatory Activity of Black Ginger (Kaempferia parviflora) through Antioxidative Activity Oxid Med Cell Longev, 2018(0):5967150.
PMID: 29849904 -
Species: Human
Sample Types: Cell Culture Supernates
A Ooki et al. (2018), Arsenic Promotes the COX2/PGE2-SOX2 Axis to Increase the Malignant Stemness Properties of Urothelial Cells Int. J. Cancer, 0(0).
PMID: 29396848 -
Species: Human
Sample Types: Tissue Culture Supernates
ME McCarthy et al. (2018), Identification of haptoglobin switch-on status in archived placental specimens indicates antenatal exposure to inflammation and potential participation of the fetus in triggering preterm birth Placenta, 62(0):50-57.
PMID: 29405967 -
Species: Equine
Sample Types: Synovial Fluid
AN Bradbery et al. (2018), Evaluation of conjugated linoleic acid (CLA) supplementation on markers of joint inflammation and cartilage metabolism in young horses challenged with lipopolysaccharide J. Anim. Sci., 0(0).
PMID: 29385470 -
Species: Mouse
Sample Types: Tissue Homogenates
JY Xiao et al. (2018), PGE2-EP3 signaling exacerbates hippocampus-dependent cognitive impairment after laparotomy by reducing expression levels of hippocampal synaptic plasticity-related proteins in aged mice CNS Neurosci Ther, 0(0).
PMID: 29488342 -
Species: Rat
Sample Types: Cell Culture Supernates
MM Rahman et al. (2018), Chondroprotective Effects of a Standardized Extract (KBH-JP-040) from Kalopanax pictus, Hericium erinaceus, and Astragalus membranaceus in Experimentally Induced In Vitro and In Vivo Osteoarthritis Models Nutrients, 10(3).
PMID: 29543781 -
Species: Human
Sample Types: Cell Culture Supernates
M Li et al. (2018), Therapeutic Delivery Specifications Identified Through Compartmental Analysis of a Mesenchymal Stromal Cell-Immune Reaction Sci Rep, 8(1):6816.
PMID: 29717209 -
Species: Human
Sample Types: THP-1 cells
HJ Park et al. (2018), Adipose-derived stem cells ameliorate colitis by suppression of inflammasome formation and regulation of M1-macrophage population through prostaglandin E2 Biochem. Biophys. Res. Commun., 0(0).
PMID: 29550474 -
Species: Mouse
Sample Types: Cell Culture Supernates
KW Kim et al. (2018), Anti-neuroinflammatory effects of cudraflavanone A isolated from the chloroform fraction of Cudrania tricuspidata root bark Pharm Biol, 56(1):192-200.
PMID: 29521141 -
Species: Human
Sample Types: Cell Culture Supernates
HK Lee et al. (2018), Effect of a Combination of Prednisone or Mycophenolate Mofetil and Mesenchymal Stem Cells on Lupus Symptoms in MRL.Faslpr Mice Stem Cells Int, 2018(0):4273107.
PMID: 30057623 -
Species: Rat
Sample Types: Cell Culture Supernates
Y Zhou et al. (2018), Dual modulation on glial cells by tetrahydroxystilbene glucoside protects against dopamine neuronal loss J Neuroinflammation, 15(1):161.
PMID: 29801454 -
Species: Human
Sample Types: Cell Culture Supernates
SG Cao et al. (2018), Cryptotanshinone inhibits prostaglandin E2 production and COX-2 expression via suppression of TLR4/NF-?B signaling pathway in LPS-stimulated Caco-2 cells Microb. Pathog., 0(0).
PMID: 29353005 -
Species: Mouse
Sample Types: Cell Culture Supernates
SJ Kim et al. (2018), Anti-inflammatory effect of Tauroursodeoxycholic acid in RAW 264.7 macrophages, Bone marrow-derived macrophages, BV2 microglial cells, and spinal cord injury Sci Rep, 8(1):3176.
PMID: 29453346 -
Species: Mouse
Sample Types: Cell Culture Supernates
JA Ocana et al. (2018), Platelet-Activating Factor-Induced Reduction in Contact Hypersensitivity Responses Is Mediated by Mast Cells via Cyclooxygenase-2-Dependent Mechanisms J. Immunol., 0(0).
PMID: 29695417 -
Species: Human
Sample Types: Cell Culture Supernates
X Jiang et al. (2018), Three macrophage subsets are identified in the uterus during early human pregnancy Cell. Mol. Immunol., 0(0).
PMID: 29618777 -
Species: Human
Sample Types: Serum
DJ Allison et al. (2017), The Influence of Chronic Inflammation on Peripheral Motor Nerve Conduction Following Spinal Cord Injury: A Randomized Clinical Trial Top Spinal Cord Inj Rehabil, 23(4):377-385.
PMID: 29339913 -
Species: Human
Sample Types: Cell Culture Supernates
K Torii et al. (2017), Combination therapy with butyrate and docosahexaenoic acid for keloid fibrogenesis: an in vitro study An Bras Dermatol, 92(2):184-190.
PMID: 28538876 -
Species: Mouse
Sample Types: Cell Culture Supernates
JM Garth et al. (2017), IL-33 Signaling Regulates Innate IL-17A and IL-22 Production via Suppression of Prostaglandin E2 during Lung Fungal Infection J. Immunol., 199(6):2140-2148.
PMID: 28784844 -
Species: Human
Sample Types: Cell Culture Supernates
S Kispert et al. (2017), Cigarette Smoke Regulates Calcium-Independent Phospholipase A2 Metabolic Pathways in Breast Cancer Am. J. Pathol., 0(0).
PMID: 28618256 -
Species: Rat
Sample Types: Serum
HS Helmy et al. (2017), Therapeutic effects of lornoxicam-loaded nanomicellar formula in experimental models of rheumatoid arthritis Int J Nanomedicine, 12(0):7015-7023.
PMID: 29026298 -
Species: Human
Sample Types: Cell Culture Supernates
A Ooki et al. (2017), YAP1 and COX2 coordinately regulate urothelial cancer stem-like cells Cancer Res., 0(0).
PMID: 29180467 -
Species: Mouse
Sample Types: Cell Culture Supernates
A Sapkota et al. (2017), Eupatilin exerts neuroprotective effects in mice with transient focal cerebral ischemia by reducing microglial activation PLoS ONE, 12(2):e0171479.
PMID: 28178289 -
Species: Mouse
Sample Types: Cell Culture Supernates
LY Lu et al. (2017), Pro-inflammatory M1 macrophages promote osteogenesis by mesenchymal stem cells via the COX-2-prostaglandin E2 pathway J. Orthop. Res, 0(0).
PMID: 28248001 -
Y Gao et al. (2017), Resolvin D1 Improves the Resolution of Inflammation via Activating NF-?B p50/p50-Mediated Cyclooxygenase-2 Expression in Acute Respiratory Distress Syndrome J. Immunol., 0(0).
PMID: 28794232 -
Species: Rat
Sample Types: Tissue Homogenates
A Paulrayer et al. (2017), Aronia melanocarpa (Black Chokeberry) Reduces Ethanol-Induced Gastric Damage via Regulation of HSP-70, NF-?B, and MCP-1 Signaling Int J Mol Sci, 18(6).
PMID: 28587230 -
Species: Mouse
Sample Types: Tissue Homogenates
L Qiang et al. (2017), Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis Autophagy, 0(0):0.
PMID: 28933598 -
Species: Mouse
Sample Types: Tissue Homogenates
SR Oh et al. (2017), Protective effect of decursin and decursinol angelate-rich Angelica gigas Nakai extract on dextran sulfate sodium-induced murine ulcerative colitis Asian Pac J Trop Med, 10(9):864-870.
PMID: 29080614 -
Species: Mouse
Sample Types: Cell Culture Supernates
L Subedi et al. (2017), Equol, a Dietary Daidzein Gut Metabolite Attenuates Microglial Activation and Potentiates Neuroprotection In Vitro Nutrients, 9(3).
PMID: 28264445 -
Species: Human
Sample Types: Cell Culture Supernates
LC Kinkead et al. (2017), Francisella novicida inhibits spontaneous apoptosis and extends human neutrophil lifespan J. Leukoc. Biol., 0(0).
PMID: 28550119 -
Species: Human
Sample Types: Cell Culture Supernates
M Fang et al. (2017), IL-33 promotes colon cancer cell stemness via JNK activation and macrophage recruitment Cancer Res, 0(0).
PMID: 28249897 -
Species: Human
Sample Types: Cell Culture Supernates
L Subedi et al. (2017), N,N-disubstituted azines attenuate LPS-mediated neuroinflammation in microglia and neuronal apoptosis via inhibiting MAPK signaling pathways BMC Neurosci, 18(1):82.
PMID: 29281977 -
Species: Human
Sample Types: Cell Culture Supernates
C Herz et al. (2017), Evaluation of an Aqueous Extract from Horseradish Root (Armoracia rusticana Radix) against Lipopolysaccharide-Induced Cellular Inflammation Reaction Evid Based Complement Alternat Med, 2017(0):1950692.
PMID: 28182113 -
Species: Mouse
Sample Types: Cell Culture Supernates
CW Cho et al. (2017), Cynanchum wilfordii Polysaccharides Suppress Dextran Sulfate Sodium-Induced Acute Colitis in Mice and the Production of Inflammatory Mediators from Macrophages Mediators Inflamm., 2017(0):3859856.
PMID: 28751820 -
Species: Rat
Sample Types: Cell Culture Supernates
Z Zhuang et al. (2017), Kaempferol Alleviates the Interleukin-1?-Induced Inflammation in Rat Osteoarthritis Chondrocytes via Suppression of NF-?B Med. Sci. Monit., 23(0):3925-3931.
PMID: 28806392 -
Species: Human
Sample Types: Cell Culture Supernates
M Kim et al. (2017), Stellera chamaejasme and its constituents induce cutaneous wound healing and anti-inflammatory activities Sci Rep, 7(0):42490.
PMID: 28220834 -
Species: Mouse
Sample Types: Cell Culture Supernates
T Lin et al. (2017), Preconditioning of murine mesenchymal stem cells synergistically enhanced immunomodulation and osteogenesis Stem Cell Res Ther, 8(1):277.
PMID: 29212557 -
Species: Human
Sample Types: Cell Culture Supernates
S Galland et al. (2017), Tumor-Derived Mesenchymal Stem Cells Use Distinct Mechanisms to Block the Activity of Natural Killer Cell Subsets Cell Rep, 20(12):2891-2905.
PMID: 28930684 -
Species: Mouse
Sample Types: Cell Culture Supernates
DH Kwon et al. (2017), Inhibitory effects on the production of inflammatory mediators and reactive oxygen species by Mori folium in lipopolysaccharide-stimulated macrophages and zebrafish An. Acad. Bras. Cienc., 89(1):661-674.
PMID: 28562828 -
Species: Mouse
Sample Types: Cell Lysates
J Jeon et al. (2017), 3'-Sialyllactose protects against osteoarthritic development by facilitating cartilage homeostasis J. Cell. Mol. Med., 0(0).
PMID: 28782172 -
Species: Human
Sample Types: Cell Culture Supernates
I Rudnik-Jan et al. (2017), Prolonged inhibition of inflammation in osteoarthritis by triamcinolone acetonide released from a polyester amide microsphere platform J Control Release, 0(0).
PMID: 28284832 -
Species: Human
Sample Types: Cell Culture Supernates
N Yao et al. (2017), Protective effect of Shenmai injection on knee articular cartilage of osteoarthritic rabbits and IL-1?-stimulated human chondrocytes Exp Ther Med, 13(6):3013-3020.
PMID: 28587374 -
Species: Human
Sample Types: Cell Culture Supernates
SA Engen et al. (2017), The oral commensal Streptococcus mitis activates the aryl hydrocarbon receptor in human oral epithelial cells Int J Oral Sci, 0(0).
PMID: 28621325 -
Species: Mouse
Sample Types: Tissue Homogenates
ATV Ho et al. (2017), Prostaglandin E2 is essential for efficacious skeletal muscle stem-cell function, augmenting regeneration and strength Proc. Natl. Acad. Sci. U.S.A., 0(0).
PMID: 28607093 -
Species: Human
Sample Types: Cell Culture Supernates
H Gao et al. (2017), Saikosaponin A inhibits IL-1?-induced inflammatory mediators in human osteoarthritis chondrocytes by activating LXR? Oncotarget, 8(51):88941-88950.
PMID: 29179489 -
Species: Human
Sample Types: Cell Culture Supernates
AM Silverstei et al. (2017), Toward understanding the role of cartilage particulates in synovial inflammation Osteoarthr. Cartil., 0(0).
PMID: 28365462 -
Species: Mouse
Sample Types: Cell Culture Supernates
A Acheva et al. (2017), Pro-inflammatory Signaling in a 3D Organotypic Skin Model after Low LET Irradiation-NF-?B, COX-2 Activation, and Impact on Cell Differentiation Front Immunol, 8(0):82.
PMID: 28239377 -
Species: Human
Sample Types: Cell Culture Supernates
L Cui et al. (2017), Chemotherapy induces ovarian cancer cell repopulation through the caspase 3-mediated arachidonic acid metabolic pathway Onco Targets Ther, 10(0):5817-5826.
PMID: 29263678 -
Species: Human
Sample Types: Cell Culture Supernates
G Qiu et al. (2017), Adipose-derived mesenchymal stem cells modulate CD14(++)CD16(+) expression on monocytes from sepsis patients in vitro via prostaglandin E2 Stem Cell Res Ther, 8(1):97.
PMID: 28446249 -
Species: Mouse
Sample Types: Cell Culture Supernates
SY Kim et al. (2017), Cheongsangbangpung-tang ameliorated the acute inflammatory response via the inhibition of NF-?B activation and MAPK phosphorylation BMC Complement Altern Med, 17(1):46.
PMID: 28086859 -
Species: Mouse
Sample Types: Serum
YK Kim et al. (2017), Tussilagone Inhibits the Inflammatory Response and Improves Survival in CLP-Induced Septic Mice Int J Mol Sci, 18(12).
PMID: 29258263 -
Species: Bovine
Sample Types: Cell Culture Supernates
AK Talukder et al. (2017), Bovine embryo induces an anti-inflammatory response in uterine epithelial cells and immune cells in vitro: possible involvement of interferon tau as an intermediator J. Reprod. Dev., 0(0).
PMID: 28603222 -
Species: Mouse
Sample Types: Cell Culture Supernates
HJ Park et al. (2017), Leaves of Raphanus sativus L. Shows Anti-Inflammatory Activity in LPS-Stimulated Macrophages via Suppression of COX-2 and iNOS Expression Prev Nutr Food Sci, 22(1):50-55.
PMID: 28401088 -
Species: Porcine
Sample Types: Tissue Culture Supernates
Y Xiao et al. (2017), Early Gut Microbiota Intervention Suppresses DSS-Induced Inflammatory Responses by Deactivating TLR/NLR Signalling in Pigs Sci Rep, 7(1):3224.
PMID: 28607413 -
Species: Mouse
Sample Types: Cell Culture Supernates
XJ Jia et al. (2017), Berbamine Exerts Anti-Inflammatory Effects via Inhibition of NF-?B and MAPK Signaling Pathways Cell. Physiol. Biochem., 41(6):2307-2318.
PMID: 28456802 -
Species: Mouse
Sample Types: Cell Culture Supernates
X Yang et al. (2017), Asperflavin, an Anti-Inflammatory Compound Produced by a Marine-Derived Fungus, Eurotium amstelodami Molecules, 22(11).
PMID: 29109367 -
Species: Rat
Sample Types: Serum
JW Jeong et al. (2017), Mori Folium water extract alleviates articular cartilage damages and inflammatory responses in monosodium iodoacetate?induced osteoarthritis rats Mol Med Rep, 0(0).
PMID: 29067461 -
Species: Mouse
Sample Types: Cell Culture Supernates
SH Kim et al. (2017), Suppressive Effect of the n-Hexane Extract of Litsea japonica Fruit Flesh on Monosodium-Iodoacetate-Induced Osteoarthritis in Rats Evid Based Complement Alternat Med, 2017(0):1791403.
PMID: 28904551 -
Species: Mouse
Sample Types: Cell Culture Supernates
SY Park et al. (2017), Anti-inflammatory effects of novel polygonum multiflorum compound via inhibiting NF-?B/MAPK and upregulating the Nrf2 pathways in LPS-stimulated microglia Neurosci. Lett., 0(0).
PMID: 28458018 -
Species: Mouse
Sample Types: Cell Culture Supernates
Y Lu et al. (2017), Oxysophocarpine reduces oxygen-glucose deprivation-induced microglial activation and injury Am J Transl Res, 9(5):2266-2275.
PMID: 28559977 -
Species: Mouse
Sample Types: Cell Culture Supernates
XR Wang et al. (2017), Glycyrrhizin inhibits LPS-induced inflammatory mediator production in endometrial epithelial cells Microb. Pathog., 0(0).
PMID: 28552807 -
Species: Human
Sample Types: Cell Culture Supernates
W Zheng et al. (2017), Silibinin protects against osteoarthritis through inhibiting the inflammatory response and cartilage matrix degradation in vitro and in vivo Oncotarget, 8(59):99649-99665.
PMID: 29245931 -
Species: Human
Sample Types: Cell Culture Supernates
J Lee et al. (2017), Use of ethanol extracts of Terminalia chebula to prevent periodontal disease induced by dental plaque bacteria BMC Complement Altern Med, 17(1):113.
PMID: 28202081 -
Species: Mouse
Sample Types: Cell Culture Supernates
HL Tuan Anh et al. (2017), Anti-inflammatory coumarins from Paramignya trimera Pharm Biol, 55(1):1195-1201.
PMID: 28245363 -
Species: Mouse
Sample Types: Cell Culture Supernates
JN Kim et al. (2017), Black soybean anthocyanins attenuate inflammatory responses by suppressing reactive oxygen species production and mitogen activated protein kinases signaling in lipopolysaccharide-stimulated macrophages Nutr Res Pract, 11(5):357-364.
PMID: 28989571 -
Species: Rat
Sample Types: Tissue Homogenates
Jun Lu (2016), Acupuncture ameliorates inflammatory response in a chronic unpredictable stress rat model of depression Brain Res. Bull, 0(0).
PMID: 27915092 -
Species: Mouse
Sample Types: Cell Culture Supernates
Jisang Park (2016), Fucoidan inhibits LPS-induced inflammation in vitro and during the acute response in vivo Int. Immunopharmacol, 43(0):91-98.
PMID: 27987467 -
Species: Human
Sample Types: Cell Culture Supernates
H Lee et al. (2016), Chondrocyte-derived extracellular matrix suppresses pathogenesis of human pterygium epithelial cells by blocking the NF-?B signaling pathways Mol. Vis, 22(0):1490-1502.
PMID: 28050122 -
Species: Rabbit
Sample Types: Cell Culture Supernates
Gwendolyn Sowa (2016), NF-?B Signaling Pathway in Controlling Intervertebral Disk Cell Response to Inflammatory and Mechanical Stressors Phys Ther, 96(5):704-11.
PMID: 26893504 -
Species: Mouse
Sample Types: Cell Lysates
S Arancibia et al. (2016), Copper oxide nanoparticles recruit macrophages and modulate nitric oxide, proinflammatory cytokines and PGE2 production through arginase activation Nanomedicine (Lond), 0(0).
PMID: 27079258 -
Species: Mouse
Sample Types: Cell Culture Supernates
Byoung-Man Kang (2016), Anti-inflammatory effect of tricin isolated from Alopecurus aequalis Sobol. on the LPS-induced inflammatory response in RAW 264.7 cells Int. J. Mol. Med, 38(5):1614-1620.
PMID: 28025993 -
Species: Mouse
Sample Types: Cell Culture Supernates
Yoonsook Kim (2016), Oryza sativa (Rice) Hull Extract Inhibits Lipopolysaccharide-Induced Inflammatory Response in RAW264.7 Macrophages by Suppressing Extracellular Signal-regulated Kinase, c-Jun N-terminal Kinase, and Nuclear Factor-?B Activation Pharmacogn Mag, 12(48):295-301.
PMID: 27867272 -
Species: Bovine
Sample Types: Cell Culture Supernates
S Danesh Mes et al. (2016), mRNA expression pattern of selected candidate genes differs in bovine oviductal epithelial cells in vitro compared with the in vivo state and during cell culture passages Reprod. Biol. Endocrinol, 14(1):44.
PMID: 27526775 -
Species: Mouse
Sample Types: Cell Culture Supernates
Farshid Guilak (2016), CRISPR/Cas9 editing of induced pluripotent stem cells for engineering inflammation-resistant tissues Arthritis rheumatology, 2016;0(0).
PMID: 27813286 -
Species: Mouse
Sample Types: Serum
(2016), Indoleamine 2,3-Dioxygenase Is Not a Pivotal Regulator Responsible for Suppressing Allergic Airway Inflammation through Adipose-Derived Stem Cells PLoS ONE, 11(11):e0165661.
PMID: 27812173 -
Species: Human
Sample Types: Cell Culture Supernates
Chan-Mi Lee (2016), Epithelium-specific Ets transcription factor-1 acts as a negative regulator of cyclooxygenase-2 in human rheumatoid arthritis synovial fibroblasts Cell Biosci, 6(0):43.
PMID: 27313839 -
Species: Mouse
Sample Types: Cell Lysates
DC Kim et al. (2016), Anti-Inflammatory and Cytoprotective Effects of TMC-256C1 from Marine-Derived Fungus Aspergillus sp. SF-6354 via up-Regulation of Heme Oxygenase-1 in Murine Hippocampal and Microglial Cell Lines Int J Mol Sci, 17(4).
PMID: 27070586 -
Species: Human
Sample Types: Plasma
(2016), Prostaglandin E2, trace elements and levels of oxidative processes in spontaneous miscarriages Eur Rev Med Pharmacol Sci, 20(22):4786-4790.
PMID: 27906421 -
Species: Human
Sample Types: Cell Culture Supernates
(2016), Tetrandrine identified in a small molecule screen to activate mesenchymal stem cells for enhanced immunomodulation Sci Rep, 6(0):30263.
PMID: 27457881 -
Species: Human
Sample Types: Cell Culture Supernates
(2016), The Role of Progesterone and a Novel Progesterone Receptor, Progesterone Receptor Membrane Component 1, in the Inflammatory Response of Fetal Membranes to Ureaplasma parvum Infection PLoS ONE, 11(12):e0168102.
PMID: 27977732 -
Species: Human
Sample Types: Cell Culture Supernates
(2016), Human Mesenchymal stem cells program macrophage plasticity by altering their metabolic status via a PGE2-dependent mechanism Sci Rep, 6(0):38308.
PMID: 27910911 -
Species: Human
Sample Types: Cell Culture Supernates
S Bruno et al. (2016), Human Liver Stem Cells Suppress T-Cell Proliferation, NK Activity, and Dendritic Cell Differentiation Stem Cells Int, 2016(0):8468549.
PMID: 27127520 -
Species: Rat
Sample Types: Cell Culture Supernates
(2016), Controlled Release of Interleukin-1 Receptor Antagonist from Hyaluronic Acid-Chitosan Microspheres Attenuates Interleukin-1?-Induced Inflammation and Apoptosis in Chondrocytes Biomed Res Int, 2016(0):6290957.
PMID: 27872853 -
Species: Human
Sample Types: Cell Culture Supernates
Lee S et al. (2016), Thymosin Beta-4 Suppresses Osteoclastic Differentiation and Inflammatory Responses in Human Periodontal Ligament Cells. PLoS ONE, 11(1):e0146708.
PMID: 26789270 -
Species: Rat
Sample Types: Tissue Homogenates
(2016), Topical Treatment With Bromfenac Reduces Retinal Gliosis and Inflammation After Optic Nerve Crush Invest. Ophthalmol. Vis. Sci., 57(14):6098-6106.
PMID: 27832276 -
Species: Human
Sample Types: Cell Culture Supernates
(2016), The role of extracellular vesicle and tunneling nanotube-mediated intercellular cross-talk between mesenchymal stem cells and human peripheral T cells Stem Cells Dev, 0(0).
PMID: 27596268 -
Species: Human
Sample Types: Cell Culture Supernates
A Malecka et al. (2016), Stromal fibroblasts support dendritic cells to maintain IL-23/Th17 responses after exposure to ionizing radiation J Leukoc Biol, 0(0).
PMID: 27049023 -
Species: Mouse
Sample Types: Cell Culture Supernates
(2016), MIF allele-dependent regulation of the MIF coreceptor CD44 and role in rheumatoid arthritis Proc. Natl. Acad. Sci. U.S.A., 113(49):E7917-E7926.
PMID: 27872288 -
Species: Human
Sample Types: Synovial Fluid
Amy L McNulty (2016), Matrix Metalloproteinase Activity and Prostaglandin E2 are Elevated in the Synovial Fluid of Meniscus Tear Patients Connect. Tissue Res., 0(0).
PMID: 27813662 -
Species: Rat
Sample Types: Cell Culture Supernates
(2016), 24R,25-Dihydroxyvitamin D3 Protects against Articular Cartilage Damage following Anterior Cruciate Ligament Transection in Male Rats PLoS ONE, 11(8):e0161782.
PMID: 27575371 -
Species: Human
Sample Types: Cell Culture Supernates
Julia Hoffmann (2016), Anti-Inflammatory Effects of Agrimoniin-Enriched Fractions of Potentilla erecta Molecules, 21(6).
PMID: 27322232 -
Species: Mouse
Sample Types: Cell Culture Supernates
Li Chang-Qing (2016), Piperine attenuates lipopolysaccharide (LPS)-induced inflammatory responses in BV2 microglia Int. Immunopharmacol., 42(0):44-48.
PMID: 27875748 -
Ines Ambite et al. (2016), Molecular Basis of Acute Cystitis Reveals Susceptibility Genes and Immunotherapeutic Targets. PloS Pathogens, 0(0):1553-7374.
PMID: 27732661 -
Species: Mouse
Sample Types: Cell Culture Supernates
(2016), Anti-Neuroinflammatory ent-Kaurane Diterpenoids from Pteris multifida Roots Molecules, 22(1).
PMID: 28035965 -
Species: Equine
Sample Types: Synovial Fluid
Maninchedda U et al. (2015), Development of an equine groove model to induce metacarpophalangeal osteoarthritis: a pilot study on 6 horses. PLoS ONE, 10(2):e0115089.
PMID: 25680102 -
Species: Mouse
Sample Types: Tissue Homogenates
Almeida C et al. (2015), Crotoxin from Crotalus durissus terrificus is able to down-modulate the acute intestinal inflammation in mice. PLoS ONE, 10(4):e0121427.
PMID: 25853847 -
Species: Mouse
Sample Types: Cell Culture Supernates
Hinden L et al. (2015), Ex Vivo Induced Regulatory Human/Murine Mesenchymal Stem Cells as Immune Modulators. Stem Cells, 33(7):2256-67.
PMID: 25850816 -
Species: Rat
Sample Types: Serum
(2015), The anti-fibrotic effects of mesenchymal stem cells on irradiated lungs via stimulating endogenous secretion of HGF and PGE2. Sci Rep, 5(0):8713.
PMID: 25736907 -
Species: Rat
Sample Types: BALF
Gu et al. (2015), Mesenchymal stem cells alleviate airway inflammation and emphysema in COPD through down-regulation of cyclooxygenase-2 via p38 and ERK MAPK pathways. Sci Rep, 5(0):8733.
PMID: 25736434 -
Species: Human
Sample Types: Cell Culture Supernates
Marentette J et al. (2015), Impaired Expression of Prostaglandin E2 (PGE2) Synthesis and Degradation Enzymes during Differentiation of Immortalized Urothelial Cells from Patients with Interstitial Cystitis/Painful Bladder Syndrome. PLoS ONE, 10(6):e0129466.
PMID: 26057882 -
Species: Human
Sample Types: Cell Culture Supernates
Li P et al. (2015), Epigenetic silencing of microRNA-149 in cancer-associated fibroblasts mediates prostaglandin E2/interleukin-6 signaling in the tumor microenvironment. Cell Res, 25(5):588-603.
PMID: 25916550 -
Species: Rat
Sample Types: Tissue Homogenates
Arab H et al. (2015), Diosmin protects against ethanol-induced gastric injury in rats: novel anti-ulcer actions. PLoS ONE, 10(3):e0122417.
PMID: 25821971 -
Species: Human
Sample Types: Cell Culture Supernates
Chowdhury B et al. (2014), Tensile strain increased COX-2 expression and PGE2 release leading to weakening of the human amniotic membrane. Placenta, 35(12):1057-64.
PMID: 25280972 -
Species: Mouse
Sample Types: Cell Culture Supernates
Delaine-Smith et al. (2014), Primary cilia respond to fluid shear stress and mediate flow-induced calcium deposition in osteoblasts. FASEB J, 28(1):430-9.
PMID: 24097311 -
Species: Rat
Sample Types: Tissue Homogenates
Arab H et al. (2014), Telmisartan attenuates colon inflammation, oxidative perturbations and apoptosis in a rat model of experimental inflammatory bowel disease. PLoS ONE, 9(5):e97193.
PMID: 24831514 -
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Plasma
Sui Y et al. (2014), Vaccine-induced myeloid cell population dampens protective immunity to SIV. J Clin Invest, 124(6):2538-49.
PMID: 24837435 -
Species: Human
Sample Types: Cell Culture Supernates
Mogami et al. (2014), Effect of thrombin on human amnion mesenchymal cells, mouse fetal membranes, and preterm birth. J Biol Chem, 289(19):13295-307.
PMID: 24652285 -
Species: Human
Sample Types: Tissue Homogenates
Yuan et al. (2014), TREM-1 is induced in tumor associated macrophages by cyclo-oxygenase pathway in human non-small cell lung cancer. PLoS ONE, 9(5):e94241.
PMID: 24842612 -
Species: Mouse
Sample Types: Cell Culture Supernates
Sidney L et al. (2014), Comparison of osteogenic differentiation of embryonic stem cells and primary osteoblasts revealed by responses to IL-1beta, TNF-alpha, and IFN-gamma. Stem Cells Dev, 23(6):605-17.
PMID: 24192281 -
Species: Mouse
Sample Types: Cell Culture Supernates
Kim K et al. (2014), Inhibitory effects of benzaldehyde derivatives from the marine fungus Eurotium sp. SF-5989 on inflammatory mediators via the induction of heme oxygenase-1 in lipopolysaccharide-stimulated RAW264.7 macrophages. Int J Mol Sci, 15(12):23749-65.
PMID: 25535073 -
Species: Mouse
Sample Types: Cell Culture Supernates
Chatterjee N et al. (2014), Leishmanial lipid suppresses the bacterial endotoxin-induced inflammatory response with attenuation of tissue injury in sepsis. J Leukoc Biol, 96(2):325-36.
PMID: 24696356 -
Species: Human
Sample Types: Cell Culture Supernates
Yamahara et al. (2014), Comparison of angiogenic, cytoprotective, and immunosuppressive properties of human amnion- and chorion-derived mesenchymal stem cells. PLoS ONE, 9(2):e88319.
PMID: 24551087 -
Species: Mouse
Sample Types: Tissue Homogenates
Schneider B et al. (2014), Lysosomal phospholipase A2: a novel player in host immunity to Mycobacterium tuberculosis. Eur J Immunol, 44(8):2394-404.
PMID: 24825529 -
Species: Mouse
Sample Types: Cell Culture Supernates
Liu Q et al. (2014), Blockade of Fas signaling in breast cancer cells suppresses tumor growth and metastasis via disruption of Fas signaling-initiated cancer-related inflammation. J Biol Chem, 289(16):11522-35.
PMID: 24627480 -
Species: Mouse
Sample Types: Serum
Li J et al. (2014), Endogenous omega-3 polyunsaturated fatty acid production confers resistance to obesity, dyslipidemia, and diabetes in mice. Mol Endocrinol, 28(8):1316-28.
PMID: 24978197 -
Species: Human
Sample Types: Serum
Aslan M et al. (2014), A pilot study investigating early postoperative changes of plasma polyunsaturated fatty acids after laparoscopic sleeve gastrectomy. Lipids Health Dis, 13(0):62.
PMID: 24694037 -
Species: Human
Sample Types: Cell Culture Supernates
Ebeling et al. (2014), From a traditional medicinal plant to a rational drug: understanding the clinically proven wound healing efficacy of birch bark extract. PLoS ONE, 9(1):e86147.
PMID: 24465925 -
Species: Human
Sample Types: Cell Culture Supernates
Otte A et al. (2014), Interference of Ca(2)(+) with the proliferation of SCCOHT-1 and ovarian adenocarcinoma cells. Int J Oncol, 45(3):1151-8.
PMID: 24969518 -
Species: Human
Sample Types: Cell Culture Supernates
Chen C et al. (2014), Telomerase governs immunomodulatory properties of mesenchymal stem cells by regulating FAS ligand expression. EMBO Mol Med, 6(3):322-34.
PMID: 24401839 -
Species: Human
Sample Types: Cell Culture Supernates
Xu X et al. (2014), Regulated expression of PTPRJ by COX-2/PGE2 axis in endothelial cells. PLoS ONE, 9(12):e114996.
PMID: 25532119 -
Species: Mouse
Sample Types: Cell Culture Supernates
Lin C et al. (2014), Pheophytin a inhibits inflammation via suppression of LPS-induced nitric oxide synthase-2, prostaglandin E2, and interleukin-1beta of macrophages. Int J Mol Sci, 15(12):22819-34.
PMID: 25501336 -
Species: Human
Sample Types: Cell Culture Supernates
Ren G et al. (2014), Rapamycin inhibits Toll-like receptor 4-induced pro-oncogenic function in head and neck squamous cell carcinoma. Oncol Rep, 31(6):2804-10.
PMID: 24737049 -
Species: Human
Sample Types: Cell Culture Supernates
Bowers L et al. (2014), NSAID use reduces breast cancer recurrence in overweight and obese women: role of prostaglandin-aromatase interactions. Cancer Res, 74(16):4446-57.
PMID: 25125682 -
Species: Mouse
Sample Types: Cell Culture Supernates
Annamanedi M et al. (2014), Celecoxib sensitizes Staphylococcus aureus to antibiotics in macrophages by modulating SIRT1. PLoS ONE, 9(6):e99285.
PMID: 24950067 -
Species: Mouse
Sample Types: Cell Culture Supernates
Huang B et al. (2014), Anti-inflammatory effects of Perilla frutescens leaf extract on lipopolysaccharide-stimulated RAW264.7 cells. Mol Med Rep, 10(2):1077-83.
PMID: 24898576 -
Species: Human
Sample Types: Cell Culture Supernates
Mace T et al. (2014), Pancreatic cancer-associated stellate cells promote differentiation of myeloid-derived suppressor cells in a STAT3-dependent manner. Cancer Res, 73(10):3007-18.
PMID: 23514705 -
Species: Human
Sample Types: Cell Culture Supernates
Yu K et al. (2014), A p38 MAPK-mediated alteration of COX-2/PGE2 regulates immunomodulatory properties in human mesenchymal stem cell aging. PLoS ONE, 9(8):e102426.
PMID: 25090227 -
Species: Human
Sample Types: Cell Culture Supernates
Zhang et al. (2014), Liver myofibroblasts from hepatitis B related liver failure patients may regulate natural killer cell function via PGE2. J Transl Med, 12(1):308.
PMID: 25367326 -
Species: Mouse
Sample Types: Cell Culture Supernates
Dang et al. (2014), Autophagy regulates the therapeutic potential of mesenchymal stem cells in experimental autoimmune encephalomyelitis. Autophagy, 10(7):1301-15.
PMID: 24905997 -
Species: Human
Sample Types: Cell Culture Supernates
Zhang M et al. (2014), Liver myofibroblasts up-regulate monocyte CD163 expression via PGE2 during hepatitis B induced liver failure. , 0(0).
PMID: 24597777 -
Species: Human
Sample Types: Cell Culture Supernates
Roeder E et al. (2014), Dose-response of superparamagnetic iron oxide labeling on mesenchymal stem cells chondrogenic differentiation: a multi-scale in vitro study. PLoS ONE, 9(5):e98451.
PMID: 24878844 -
Species: Equine
Sample Types: Cell Culture Supernates
Carrade Holt D et al. (2014), Equine mesenchymal stem cells inhibit T cell proliferation through different mechanisms depending on tissue source. Stem Cells Dev, 23(11):1258-65.
PMID: 24438346 -
Species: Human
Sample Types: Cell Culture Supernates
Theoduloz et al. (2013), Diterpenylquinone hybrids: synthesis and assessment of gastroprotective mechanisms of action in human cells. Molecules, 18(9):11044-66.
PMID: 24025455 -
Species: Human
Sample Types: Cell Culture Supernates
Shin S et al. (2013), Antagonizing effects and mechanisms of afzelin against UVB-induced cell damage. PLoS ONE, 8(4):e61971.
PMID: 23626759 -
Species: Human
Sample Types: Cell Culture Supernates
Jung et al. (2013), Madecassoside inhibits melanin synthesis by blocking ultraviolet-induced inflammation. Molecules, 18(12):15724-36.
PMID: 24352025 -
Species: Human
Sample Types: Cell Culture Supernates
Conforti A et al. (2013), Biological, functional and genetic characterization of bone marrow-derived mesenchymal stromal cells from pediatric patients affected by acute lymphoblastic leukemia. PLoS ONE, 8(11):e76989.
PMID: 24244271 -
Species: Human
Sample Types: Cell Culture Supernates
Mogami H et al. (2013), Fetal fibronectin signaling induces matrix metalloproteases and cyclooxygenase-2 (COX-2) in amnion cells and preterm birth in mice. J Biol Chem, 288(3):1953-66.
PMID: 23184961 -
Species: Rat
Sample Types: Plasma
Wan et al. (2013), Sex difference in urocortin production is contributory to the gender disparity in a rat model of vasculitis induced by sodium laurate. Endocrinology, 154(12):4663-74.
PMID: 24064363 -
Species: Human
Sample Types: Cell Culture Supernates
Iachininoto M et al. (2013), Cyclooxygenase-2 (COX-2) inhibition constrains indoleamine 2,3-dioxygenase 1 (IDO1) activity in acute myeloid leukaemia cells. Molecules, 18(9):10132-45.
PMID: 23973990 -
Species: Mouse
Sample Types: Cell Culture Supernates
Matysiak et al. (2013), MicroRNA-146a negatively regulates the immunoregulatory activity of bone marrow stem cells by targeting prostaglandin E2 synthase-2. J Immunol, 190(10):5102-9.
PMID: 23589616 -
Species: Human
Sample Types: Serum
Aslan M et al. (2013), LC-MS/MS analysis of plasma polyunsaturated fatty acids in type 2 diabetic patients after insulin analog initiation therapy. Lipids Health Dis, 12(0):169.
PMID: 24195588 -
Species: Rat
Sample Types: Tissue Homogenates
Harmel E et al. (2013), AMPK in the small intestine in normal and pathophysiological conditions. Endocrinology, 155(3):873-88.
PMID: 24424053 -
Species: Human
Sample Types: Cell Culture Supernates
Manferdini C et al. (2013), Adipose-derived mesenchymal stem cells exert antiinflammatory effects on chondrocytes and synoviocytes from osteoarthritis patients through prostaglandin E2. Arthritis Rheum, 65(5):1271-81.
PMID: 23613363 -
Species: Mouse
Sample Types: Cell Culture Supernates
Ylostalo J et al. (2012), Human mesenchymal stem/stromal cells cultured as spheroids are self-activated to produce prostaglandin E2 that directs stimulated macrophages into an anti-inflammatory phenotype. Stem Cells, 30(10):2283-96.
PMID: 22865689 -
Species: Mouse
Sample Types: Cell Culture Supernates
Zong Y et al. (2012), Resveratrol inhibits LPS-induced MAPKs activation via activation of the phosphatidylinositol 3-kinase pathway in murine RAW 264.7 macrophage cells. PLoS ONE, 7(8):e44107.
PMID: 22952890 -
Species: Mouse
Sample Types: Cell Culture Supernates
Herranz S et al. (2012), Role of the tumor suppressor ARF in macrophage polarization: Enhancement of the M2 phenotype in ARF-deficient mice. Oncoimmunology, 1(8):1227-1238.
PMID: 23243586 -
Species: Human
Sample Types: Cell Culture Supernates
Wang JH et al. (2012), Anti-arthritic effects of magnolol in human interleukin 1β-stimulated fibroblast-like synoviocytes and in a rat arthritis model. PLoS ONE, 7(2):e31368.
PMID: 22359588 -
Species: Human
Sample Types: Serum
Liu L et al. (2012), Influenza A virus induces interleukin-27 through cyclooxygenase-2 and protein kinase A signaling. J. Biol. Chem., 287(15):11899-910.
PMID: 22343630 -
Species: Mouse
Sample Types: Tissue Homogenates
Gottfries J et al. (2012), Modelling of mouse experimental colitis by global property screens: a holistic approach to assess drug effects in inflammatory bowel disease. PLoS ONE, 7(1):e30005.
PMID: 22279558 -
Species: Human
Sample Types: Cell Culture Supernates
Abdelrazik H et al. (2011), Mesenchymal stem cells expanded in human platelet lysate display a decreased inhibitory capacity on T- and NK-cell proliferation and function. Eur. J. Immunol., 41(11):3281-90.
PMID: 21874650 -
Species: Canine
Sample Types: Cell Culture Supernates
Rai MF et al. (2011), Evidence for regulated interleukin-4 expression in chondrocyte-scaffolds under in vitro inflammatory conditions. PLoS ONE, 6(10):e25749.
PMID: 21991344 -
Species: Mouse
Sample Types: Tissue Homogenates
Li N et al. (2011), Serotonin activates dendritic cell function in the context of gut inflammation. Am. J. Pathol., 178(2):662-71.
PMID: 21281798 -
Species: Mouse
Sample Types: Cell Culture Supernates
Oliveira CJ et al. (2011), Deconstructing tick saliva: non-protein molecules with potent immunomodulatory properties. J. Biol. Chem., 286(13):10960-9.
PMID: 21270122 -
Species: Human
Sample Types: Cell Culture Supernates
Verma S et al. (2011), Cyclooxygenase-2 inhibitor blocks the production of West Nile virus-induced neuroinflammatory markers in astrocytes. J. Gen. Virol., 92(0):507-15.
PMID: 21106803 -
Species: Rat
Sample Types: Cell Culture Supernates
Zhao Z et al. (2011), Inhibition of cPLA2 activation by Ginkgo biloba extract protects spinal cord neurons from glutamate excitotoxicity and oxidative stress-induced cell death. J. Neurochem., 116(6):1057-65.
PMID: 21182525 -
Species: Human
Sample Types: Cell Culture Supernates
Rydkina E et al. (2010), Rickettsia rickettsii infection of human macrovascular and microvascular endothelial cells reveals activation of both common and cell type-specific host response mechanisms. Infect. Immun., 78(6):2599-606.
PMID: 20385756 -
Species: Mouse
Sample Types: Cell Culture Supernates
Nakajima S et al. (2010), Prostaglandin I2-IP signaling promotes Th1 differentiation in a mouse model of contact hypersensitivity. J. Immunol., 184(10):5595-603.
PMID: 20400695 -
Species: Mouse
Sample Types: BALF
Niwa S et al. (2010), Ovalbumin-induced plasma interleukin-4 levels are reduced in ceramide kinase-deficient DO11.10 RAG1-/- mice. Lipids Health Dis, 9(0):1.
PMID: 20053284 -
Species: Human
Sample Types: Cell Culture Supernates
Gadgeel SM et al. (2009), Genistein enhances the effect of epidermal growth factor receptor tyrosine kinase inhibitors and inhibits nuclear factor kappa B in nonsmall cell lung cancer cell lines. Cancer, 115(10):2165-76.
PMID: 19288574 -
Species: Human
Sample Types: Cell Culture Supernates
Campeau PM et al. (2009), Characterization of Gaucher disease bone marrow mesenchymal stromal cells reveals an altered inflammatory secretome. Blood, 114(15):3181-90.
PMID: 19587377 -
Species: Mouse
Sample Types: Cell Culture Supernates
Lee SH et al. (2009), Arachidonic acid potentiates hypoxia-induced VEGF expression in mouse embryonic stem cells: involvement of Notch, Wnt, and HIF-1alpha. Am. J. Physiol., Cell Physiol., 297(1):C207-16.
PMID: 19339510 -
Species: Mouse
Sample Types: Serum
Yamaguchi T et al. (2009), Fra-1/AP-1 impairs inflammatory responses and chondrogenesis in fracture healing. J. Bone Miner. Res., 24(12):2056-65.
PMID: 19558315 -
Species: Rat
Sample Types: Tissue Homogenates
Souza Mdo C et al. (2009), In vitro and in vivo anti-Helicobacter pylori activity of Calophyllum brasiliense Camb. J Ethnopharmacol, 123(3):452-8.
PMID: 19501278 -
Species: Mouse
Sample Types: Cell Culture Supernates
Cheon MS et al. (2009), Chrysanthemum indicum Linne extract inhibits the inflammatory response by suppressing NF-kappaB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophages. J Ethnopharmacol, 122(3):473-7.
PMID: 19429315 -
Species: Porcine
Sample Types: Cell Culture Supernates
Luna C et al. (2009), Extracellular release of ATP mediated by cyclic mechanical stress leads to mobilization of AA in trabecular meshwork cells. Invest. Ophthalmol. Vis. Sci., 50(12):5805-10.
PMID: 19608543 -
Species: Rabbit
Sample Types: Serum
Huh JE et al. (2009), Protective effects of butanol fraction from Betula Platyphyla var. japonica on cartilage alterations in a rabbit collagenase-induced osteoarthritis. J Ethnopharmacol, 123(3):515-21.
PMID: 18817862 -
Species: Human
Sample Types: Cell Culture Supernates
Degagne E et al. (2009), P2Y2 receptor transcription is increased by NF-kappa B and stimulates cyclooxygenase-2 expression and PGE2 released by intestinal epithelial cells. J. Immunol., 183(7):4521-9.
PMID: 19734210 -
Species: Rabbit
Sample Types: Serum
Park DS et al. (2009), Therapeutic effect of Aralia cordata extracts on cartilage protection in collagenase-induced inflammatory arthritis rabbit model. J Ethnopharmacol, 125(2):207-17.
PMID: 19619632 -
Species: Mouse
Sample Types: Cell Culture Supernates
Highfill SL et al. (2009), Multipotent adult progenitor cells can suppress graft-versus-host disease via prostaglandin E2 synthesis and only if localized to sites of allopriming. Blood, 114(3):693-701.
PMID: 19458354 -
Species: Mouse
Sample Types: BALF
Mayer K et al. (2009), Acute lung injury is reduced in fat-1 mice endogenously synthesizing n-3 fatty acids. Am. J. Respir. Crit. Care Med., 179(6):474-83.
PMID: 19136374 -
Species: Rat
Sample Types: Tissue Homogenates
Sanchez-Lemus E et al. (2009), In vivo Angiotensin II AT1 receptor blockade selectively inhibits LPS-induced innate immune response and ACTH release in rat pituitary gland. Brain Behav. Immun., 23(7):945-57.
PMID: 19427376 -
Species: Mouse
Sample Types: Cell Culture Supernates
Pae HO et al. (2008), Tranilast, an orally active anti-allergic drug, up-regulates the anti-inflammatory heme oxygenase-1 expression but down-regulates the pro-inflammatory cyclooxygenase-2 and inducible nitric oxide synthase expression in RAW264.7 macrophages. Biochem. Biophys. Res. Commun., 371(3):361-5.
PMID: 18435907 -
Species: Human
Sample Types: Plasma
Castellano G et al. (2008), Activation of the osteopontin/matrix metalloproteinase-9 pathway correlates with prostate cancer progression. Clin. Cancer Res., 14(22):7470-80.
PMID: 19010864 -
Species: Mouse
Sample Types: Tissue Homogenates
Zhou W et al. (2008), Cyclooxygenase inhibition during allergic sensitization increases STAT6-independent primary and memory Th2 responses. J. Immunol., 181(8):5360-7.
PMID: 18832692 -
Species: Mouse
Sample Types: BALF
Li Q et al. (2008), Pulmonary stromal cells induce the generation of regulatory DC attenuating T-cell-mediated lung inflammation. Eur. J. Immunol., 38(10):2751-61.
PMID: 18825748 -
Species: Human
Sample Types: Plasma
Gomez-Hernandez A et al. (2008), Effect of intensive atorvastatin therapy on prostaglandin E2 levels and metalloproteinase-9 activity in the plasma of patients with non-ST-elevation acute coronary syndrome. Am. J. Cardiol., 102(1):12-8.
PMID: 18572029 -
Species: Mouse
Sample Types: Cell Culture Supernates
Reddi D et al. (2008), Porphyromonas gingivalis regulates the RANKL-OPG system in bone marrow stromal cells. Microbes Infect., 10(14):1459-68.
PMID: 18789397 -
Species: Human
Sample Types: Cell Culture Supernates
Liotta F et al. (2007), Toll-like receptors 3 and 4 are expressed by human bone marrow-derived mesenchymal stem cells and can inhibit their T-cell modulatory activity by impairing Notch signaling. Stem Cells, 26(1):279-89.
PMID: 17962701 -
Species: Mouse
Sample Types: Serum
Niki Y et al. (2007), Administration of cyclooxygenase-2 inhibitor reduces joint inflammation but exacerbates osteopenia in IL-1 alpha transgenic mice due to GM-CSF overproduction. J. Immunol., 179(1):639-46.
PMID: 17579086 -
Species: Porcine
Sample Types: Cell Culture Supernates
Hennerbichler A et al. (2007), Regional differences in prostaglandin E2 and nitric oxide production in the knee meniscus in response to dynamic compression. Biochem. Biophys. Res. Commun., 358(4):1047-53.
PMID: 17517372 -
Species: Rat
Sample Types: CSF
Machado RR et al. (2007), CCR1 and CCR5 chemokine receptors are involved in fever induced by LPS (E. coli) and RANTES in rats. Brain Res., 1161(0):21-31.
PMID: 17604006 -
Species: Mouse
Sample Types: BALF
Gupta N et al. (2007), Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice. J. Immunol., 179(3):1855-63.
PMID: 17641052 -
Species: Bovine
Sample Types: Cell Culture Supernates
Tam CL et al. (2007), Requirement for protein kinase R in interleukin-1alpha-stimulated effects in cartilage. Biochem. Pharmacol., 74(11):1636-41.
PMID: 17850766 -
Species: Rat
Sample Types: Tissue Homogenates
Nandi J et al. (2007), 5-aminosalicylic acid improves indomethacin-induced enteropathy by inhibiting iNOS transcription in rats. Dig. Dis. Sci., 53(1):123-32.
PMID: 17503181 -
Species: Human
Sample Types: Cell Culture Supernates
Mendes R et al. (0), Endothelial Cell Response to Fusobacterium nucleatum. Infect Immu84(7):2141-8.
PMID: 27185790 -
Species: Canine
Sample Types: Cell Culture Supernates
Clark K et al. (0), Canine and Equine Mesenchymal Stem Cells Grown in Serum Free Media Have Altered Immunophenotype. Stem Cell Re12(2):245-56.
PMID: 26638159
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Customer Reviews (8)
3.9 out of 5
8 customer ratings
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Sample Tested: SerumVerified Customer | Posted 02/05/2022This kit is really great and easy to use!
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Sample Tested: Cell Culture SamplesVerified Customer | Posted 01/16/2022It performed really good and repeatable.
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Sample Tested: Cell culture supernatantVerified Customer | Posted 04/03/2021High variability between replicates. Perhaps the most common issue with the kit is the requirement to complete the assay with a specific microplate shaker- which is how the assay was developed and QC tested, this is a horizontal orbital microplate shaker (0.12 inches or 3mm orbit) set at 500 ± 50 rpm.
Bio-Techne ResponseThank you for reviewing our product. We are sorry to that that this product did not perform as expected. We have been in touch with the customer to resolve this issue according to our Product Guarantee and to the customer’s satisfaction. -
Sample Tested: Cell culture supernatantVerified Customer | Posted 11/04/2020I had trouble replicating the standard curve
Bio-Techne ResponseThank you for reviewing our product. We are sorry to that that this product did not perform as expected. We have been in touch with the customer to resolve this issue according to our Product Guarantee and to the customer’s satisfaction. -
Sample Tested: Cell Culture SupernatesVerified Customer | Posted 11/07/2019
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Sample Tested: Cell Culture MediaVerified Customer | Posted 11/03/2017Very easy to use, reliable results
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Sample Tested: Adipose tissueVerified Customer | Posted 05/02/2017
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Sample Tested: Mesenchymal stem cellsVerified Customer | Posted 06/21/2016
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FAQs
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How should the indomethacin be prepared, prior to being added to the serum or plasma collection tubes?
First, dissolve indomethacin (Tocris cat # 1708) in ethanol to 10 mg/mL. Then, dilute indomethacin solution 1:50 in 1X PBS (to 0.2 mg/mL). Finally, inject 0.2 mg/mL indomethacin solution into vacutainer tube immediately following blood draw, to a final concentration of 10 μg/mL.
⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.
