Does this assay recognize total or free IGF-I?

Name: Mouse/Rat IGF-I/IGF-1 Quantikine ELISA Kit
Brand: R&D Systems
SKU: MG100
Rating: 5 (8 reviews)

This assay measures total IGF-I. IGF-I bound to IGF Binding Proteins and free IGF-I are detected.

Mouse/Rat IGF-I/IGF-1 Quantikine ELISA Kit Best Seller

Catalog # MG100 | R&D Systems, Inc. a Bio-Techne Brand

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Citations (169)

Product Datasheet / COA / SDS

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Key Product Details

Assay Length:	4.5 hours
Sample Type & Volume Required Per Well:	Cell Culture Supernates (25 uL), Tissue Homogenates (50 uL), Serum (10 uL), EDTA Plasma (10 uL), Heparin Plasma (10 uL)
Sensitivity:	8.4 pg/mL
Assay Range:	31.2 - 2,000 pg/mL (Cell Culture Supernates, Tissue Homogenates, Serum, EDTA Plasma, Heparin Plasma)
Mouse/Rat IGF-I/IGF-1 Quantikine ELISA Kit Summary:	The Quantikine Mouse/Rat IGF-I Immunoassay is a 4.5 hour solid-phase ELISA designed to measure mouse and rat IGF-I in cell culture supernates, tissue homogenates, serum, and plasma. It contains E. coli-expressed recombinant mouse IGF-I and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant factor. Results obtained using natural mouse and rat IGF-I showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring mouse/rat IGF-I.

View Full Technical Details for Mouse/Rat IGF-I/IGF-1 Quantikine ELISA Kit

Technical Data
Citations (169) / Reviews (8) / FAQs

Product Specifications for Mouse/Rat IGF-I/IGF-1 Quantikine ELISA Kit

Assay Type	Solid Phase Sandwich ELISA
Format	96-well strip plate
Measurement	Quantitative ELISA
Detection Method	Colorimetric - 450nm (TMB)
Conjugate	HRP
Reactivity	Mouse, Rat
Specificity	Natural and recombinant mouse and rat IGF-I
Cross-reactivity	< 0.5% cross-reactivity observed with available related molecules. < 50% cross-species reactivity observed with species tested.
Interference	No significant interference observed with available related molecules.

Precision

Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision

Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision

Cell Culture Supernates, Tissue Homogenates, Serum, EDTA Plasma, Heparin Plasma

	Intra-Assay Precision			Inter-Assay Precision
Sample	1	2	3	1	2	3
n	20	20	20	35	35	35
Mean (pg/mL)	82	269	921	86	256	863
Standard Deviation	4.6	8.9	37.7	7.8	11.8	37.4
CV%	5.6	3.3	4.1	9.1	4.6	4.3

Recovery

The recovery of mouse/rat IGF-I spiked to three levels throughout the range of the assay in the cell culture supernate samples was evaluated.

Sample Type	Average % Recovery	Range %
Mouse Cell Culture Supernates (n=7)	98	89-111
Rat Cell Culture Supernates (n=6)	98	82-108

Linearity

To assess the linearity of the assay, samples containing mouse or rat IGF-I in each matrix were diluted with Calibrator Diluent and then assayed.

Scientific Data Examples for Mouse/Rat IGF-I/IGF-1 Quantikine ELISA Kit

	Mouse/Rat IGF-I ELISA Standard Curve

Preparation and Storage

Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IGF-I/IGF-1

Insulin-like Growth Factor 1 (IGF-1), also known as somatomedin C, is a member of the insulin superfamily. It was originally discovered as a mediator of growth hormone actions on somatic cell growth, but has also been shown to be an important regulator of cell metabolism, differentiation and survival. IGF-1 is synthesized as a preproprotein that is proteolytically cleaved to generate the mature protein linked by three disulfide bonds. Mature IGF-1 is highly conserved among large mammals, with 100% sequence identity between the human, bovine, porcine, equine, and canine proteins.

Mature mouse IGF-1 is a non-glycosylated, 70 amino acid (aa) secreted polypeptide that is derived from either a 153 aa or a 159 aa preproprotein. It shares 99% and 94% aa sequence identity with rat and human IGF-1, respectively. IGF-1 is synthesized in the liver and other tissues. It is found in blood and other body fluids as a complex with specific high affinity IGF binding proteins (IGFBP-1 to -6). The IGFBPs are expressed in specific patterns during development. They are modulators of IGF actions, which control IGF bioavailability to specific cell-surface receptors. Their functions are further regulated by IGFBP proteases, which proteolytically cleave the IGFBPs to lower the affinity with which they bind IGFs and increase IGF bioavailability. Some IGFBPs also have IGF-Independent effects on cell functions. IGF-Independent circulates primarily as a ternary complex with IGFBP-3 or IGFBP-5 and the acid-labile subunit (ALS). Some IGF-1 is also present in binary complexes with other IGFBPs. Whereas the ternary complexes are generally restricted to the vasculature, the binary complexes freely enter the tissues.

IGF-1 actions are mediated by two ubiquitously expressed receptor tyrosine kinases: IGF-I R and Insulin R/CD220. IGF-I R and Insulin R are disulfide-linked heterotetrameric complexes that consist of two alpha and two beta subunits. For both of these receptors, the prepro proteins are cleaved to produce extracellular alpha subunits which contain a cysteine-rich region and ligand-binding fibronectin type III (FN-III) domains, and beta subunits which contain an extracellular FN-III domain, transmembrane, and cytoplasmic tyrosine kinase domains. A hybrid complex containing one IGF-I R and one Insulin R also serves as a functional high affinity receptor for IGF-1. IGF-I R-Insulin R hybrids respond primarily to IGF-1, potentially downregulating the cellular response to Insulin. IGF signaling is also modulated by IGF binding proteins and the scavenger receptor, IGF-I I R.

Item	Value
Long Name	Insulin-like Growth Factor I/Insulin-like Growth Factor 1
Entrez Gene IDs	3479 (Human); 16000 (Mouse); 24482 (Rat)
Alternate Names	IBP1, IGF-1, IGF-I, IGF-IA, IGF-IB, IGF1, IGF1A, IGFI, MGF, Mechano growth factor, Somatomedin A, Somatomedin C, insulin-like growth factor 1, insulin-like growth factor 1 (somatomedin C), insulin-like growth factor I, insulin-like growth factor IA, insulin-like growth factor IB, somatomedin-C

Citations for Mouse/Rat IGF-I/IGF-1 Quantikine ELISA Kit (169)

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Citations are publications that use Bio-Techne products. Selected citations for Mouse/Rat IGF-I/IGF-1 Quantikine ELISA Kit include:

Species: Mouse
Sample Types: Plasma

Stroup et al. (2023-07-24), Delayed skeletal development and IGF-1 deficiency in a mouse model of lysinuric protein intolerance Disease models mechanisms
PMID: 37486182
Species: Mouse
Sample Types: Serum

O'Brien et al. (2023-06-30), The super-healing MRL strain promotes muscle growth in muscular dystrophy through a regenerative extracellular matrix bioRxiv : the preprint server for biology
PMID: 37425960
Species: Mouse
Sample Types: Serum

CLM Ludwig et al. (2023-02-04), Alterations in gonadotropin, apoptotic and metabolic pathways in granulosa cells warrant superior fertility of the Dummerstorf high fertility mouse line 1 Journal of ovarian research, 2023-016(1):32.
PMID: 36739419
Species: Mouse
Sample Types: Serum

T Hirabayash et al. (2023-01-30), Hepatic phosphatidylcholine catabolism driven by PNPLA7 and PNPLA8 supplies endogenous choline to replenish the methionine cycle with methyl groups Cell Reports, 2023-042(2):111940.
PMID: 36719796
Species: Mouse
Sample Types: Serum

X Gao et al. (2023-01-25), MRL/MpJ Mice Resist to Age-Related and Long-Term Ovariectomy-Induced Bone Loss: Implications for Bone Regeneration and Repair International Journal of Molecular Sciences, 2023-024(3).
PMID: 36768718
Species: Bovine
Sample Types: Cell Culture Supernates

K Yamanaka et al. (2023-01-10), Development of serum-free and grain-derived-nutrient-free medium using microalga-derived nutrients and mammalian cell-secreted growth factors for sustainable cultured meat production Scientific Reports, 2023-013(1):498.
PMID: 36627406
Species: Mouse
Sample Types: Plasma

JY Kim-Muller et al. (2023-01-10), GDF15 neutralization restores muscle function and physical performance in a mouse model of cancer cachexia Cell Reports, 2023-042(1):111947.
PMID: 36640326
Species: Mouse
Sample Types: Serum

X Gao et al. (2023), MRL/MpJ Mice Resist to Age-Related and Long-Term Ovariectomy-Induced Bone Loss: Implications for Bone Regeneration and Repair International Journal of Molecular Sciences, 24(3).
PMID: 36768718
Species: Mouse
Sample Types: Plasma

J Wang et al. (2022-12-28), Bone marrow-derived IGF-1 orchestrates maintenance and regeneration of the adult skeleton Proceedings of the National Academy of Sciences of the United States of America, 2022-1120(1):e2203779120.
PMID: 36577075
Species: Rat
Sample Types: Tissue Homogenates

N Hamadi et al. (2022-12-22), Stereological Evidence of Non-Selective Hippocampal Neurodegeneration, IGF-1 Depletion, and Behavioral Deficit following Short Term Bilateral Adrenalectomy in Wistar Rats Biomolecules, 2022-113(1).
PMID: 36671407
Species: Rat
Sample Types: Serum

S Ma et al. (2022-12-12), Transcriptome and Methylome Profiling in Rat Skeletal Muscle: Impact of Post-Weaning Protein Restriction International Journal of Molecular Sciences, 2022-123(24).
PMID: 36555412
Species: Mouse
Sample Types: Cell Culture Supernates

Z Liu et al. (2022-12-08), Single-cell transcriptome analyses reveal microglia types associated with proliferative retinopathy JCI Insight, 2022-17(23).
PMID: 36264636
Species: Mouse
Sample Types: Serum

L Xiao et al. (2022-11-30), Bone loss is ameliorated by fecal microbiota transplantation through SCFA/GPR41/ IGF1 pathway in sickle cell disease mice Scientific Reports, 2022-112(1):20638.
PMID: 36450880
Species: Rat
Sample Types: Cell Culture Supernates

I Klein et al. (2022-11-02), Glia from the central and peripheral nervous system are differentially affected by paclitaxel chemotherapy via modulating their neuroinflammatory and neuroregenerative properties Frontiers in Pharmacology, 2022-113(0):1038285.
PMID: 36408236
Species: Mouse
Sample Types: Cell Culture Supernates

A Hiroto et al. (2022-11-02), Stromal androgen signaling acts as tumor niches to drive prostatic basal epithelial progenitor-initiated oncogenesis Nature Communications, 2022-113(1):6552.
PMID: 36323713
Species: Mouse
Sample Types: Serum

S Takata et al. (2022-10-30), LIF-IGF Axis Contributes to the Proliferation of Neural Progenitor Cells in Developing Rat Cerebrum International Journal of Molecular Sciences, 2022-123(21).
PMID: 36361987
Species: Mouse
Sample Types: Tissue Homogenates

MP LaPierre et al. (2022-09-29), MicroRNA-7 regulates melanocortin circuits involved in mammalian energy homeostasis Nature Communications, 2022-013(1):5733.
PMID: 36175420
Species: Rat
Sample Types: Serum

MM Nowacka-Ch et al. (2022-05-05), Global Proteome Profiling of the Temporal Cortex of Female Rats Exposed to Chronic Stress and the Western Diet Nutrients, 2022-014(9).
PMID: 35565902
Species: Mouse, Rat
Sample Types: Serum

H Nishi et al. (2022-05-02), Essential Amino Acid Intake Is Required for Sustaining Serum Insulin-like Growth Factor-I Levels but Is Not Necessarily Needed for Body Growth Cells, 2022-011(9).
PMID: 35563827
Species: Rat
Sample Types: Plasma

SH Lee et al. (2022-03-12), Magnetically actuating implantable pump for the on-demand and needle-free administration of human growth hormone International journal of pharmaceutics, 2022-0618(0):121664.
PMID: 35292393
Species: Mouse
Sample Types: Serum

E Mendes de et al. (2022-03-11), Acute Inflammation Is a Predisposing Factor for Weight Gain and Insulin Resistance Pharmaceutics, 2022-014(3).
PMID: 35335996
Species: Rat
Sample Types: Plasma

J Dereke et al. (2022-03-08), Structural and immunoendocrine remodeling in gut, pancreas and thymus in weaning rats fed powdered milk diets rich in Maillard reactants Scientific Reports, 2022-012(1):4039.
PMID: 35260716
Species: Mouse
Sample Types: Serum

T Yamamotoya et al. (2022-02-04), Involvement of neuronal and muscular Trk-fused gene (TFG) defects in the development of neurodegenerative diseases Scientific Reports, 2022-012(1):1966.
PMID: 35121777
Species: Mouse
Sample Types: Serum

F D'Addio et al. (2022-02-03), The IGFBP3/TMEM219 pathway regulates beta cell homeostasis Nature Communications, 2022-013(1):684.
PMID: 35115561
Species: Mouse
Sample Types: Serum

YY Sung et al. (2022-01-19), Combined Phyllostachys pubescens and Scutellaria baicalensis Prevent High-Fat Diet-Induced Obesity via Upregulating Thermogenesis and Energy Expenditure by UCP1 in Male C57BL/6J Mice Nutrients, 2022-014(3).
PMID: 35276805
Species: Rat
Sample Types: Serum

KH Kim et al. (2022-01-05), Metabolic Rewiring by Human Placenta-Derived Mesenchymal Stem Cell Therapy Promotes Rejuvenation in Aged Female Rats International Journal of Molecular Sciences, 2022-023(1).
PMID: 35008991
Species: Mouse
Sample Types: Serum

M Darnaud et al. (2021-11-18), A standardized gnotobiotic mouse model harboring a minimal 15-member mouse gut microbiota recapitulates SOPF/SPF phenotypes Nature Communications, 2021-112(1):6686.
PMID: 34795236
Species: Mouse
Sample Types: Serum

LCD Pomatto-Wa et al. (2021-10-27), Daily caloric restriction limits tumor growth more effectively than caloric cycling regardless of dietary composition Nature Communications, 2021-112(1):6201.
PMID: 34707136
Species: Mouse
Sample Types: Tissue Homogenate

K Kurup et al. (2021-09-29), Litter expansion alters metabolic homeostasis in a sex specific manner PLoS ONE, 2021-016(9):e0237199.
PMID: 34587168
Species: Rat
Sample Types: Tissue Homogenates

BK Schilling et al. (2021-09-19), Intramuscular injection of skeletal muscle derived extracellular matrix mitigates denervation atrophy after sciatic nerve transection Journal of tissue engineering, 2021-012(0):2041731421103.
PMID: 34567507
Species: Transgenic Mouse
Sample Types: Serum

P Maity et al. (2021-08-31), Persistent JunB activation in fibroblasts disrupts stem cell niche interactions enforcing skin aging Cell Reports, 2021-036(9):109634.
PMID: 34469740
Species: Mouse
Sample Types: Tissue Homogenates

HJ Kok et al. (2021-07-19), Muscle insulin-like growth factor-I modulates murine craniofacial bone growth European cells materials, 2021-07-19;41(0):72-89.
PMID: 34279041
Species: Mouse
Sample Types: Cell Culture Supernates

S Ock et al. (2021-07-09), IGF-1 protects against angiotensin II-induced cardiac fibrosis by targeting alphaSMA Cell Death Disease, 2021-07-09;12(7):688.
PMID: 34244467
Species: Rat
Sample Types: Serum

AS Alshinnawy et al. (2021-06-01), Telomerase activator-65 and pomegranate peel improved the health status of the liver in aged rats; multi-targets involved Iranian journal of basic medical sciences, 2021-024(6):842-850.
PMID: 34630962
Species: Mouse
Sample Types: Plasma

O Nychyk et al. (2021-05-11), Protein quality and quantity influence the effect of dietary fat on weight gain and tissue partitioning via host-microbiota changes Cell Reports, 2021-035(6):109093.
PMID: 33979605
Species: Mouse
Sample Types: Plasma

JD Plummer et al. (2021-03-30), Selenium supplementation inhibits IGF-1 signaling and confers methionine restriction-like healthspan benefits to mice Elife, 2021-010(0).
PMID: 33783357
Species: Mouse
Sample Types: Serum

M Icyuz et al. (2021-03-23), Physiological and metabolic characteristics of novel double-mutant female mice with targeted disruption of both growth hormone-releasing hormone and growth hormone receptor Aging Cell, 2021-00(0):e13339.
PMID: 33755309
Species: Mouse
Sample Types: Serum

DW Dodington et al. (2021-03-08), JAK2-IGF1 axis in osteoclasts regulates postnatal growth in mice JCI Insight, 2021-06(5).
PMID: 33682794
Species: Rat
Sample Types: Serum

MM Elshemy et al. (2021-02-02), Antioxidative Capacity of Liver- and Adipose-Derived Mesenchymal Stem Cell-Conditioned Media and Their Applicability in Treatment of Type 2 Diabetic Rats Oxidative Medicine and Cellular Longevity, 2021-02021(0):8833467.
PMID: 33623636
Species: Rat
Sample Types: Serum

SL Hsu et al. (2020-12-15), Shockwave Therapy Modulates the Expression of BMP2 for Prevention of Bone and Cartilage Loss in the Lower Limbs of Postmenopausal Osteoporosis Rat Model Biomedicines, 2020-18(12).
PMID: 33333838
Species: Mouse
Sample Types: Serum

SM Grundmann et al. (2020-11-27), High-phosphorus diets reduce aortic lesions and cardiomyocyte size and modify lipid metabolism in Ldl receptor knockout mice Sci Rep, 2020-110(1):20748.
PMID: 33247205
Species: Rat
Sample Types: Plasma

M Portero-Tr et al. (2020-11-09), Caloric restriction modulates the monoaminergic system and metabolic hormones in aged rats Sci Rep, 2020-110(1):19299.
PMID: 33168891
Species: Rat
Sample Types: Cell Culture Supernates

SJ Blaschke et al. (2020-11-05), Substrate Elasticity Exerts Functional Effects on Primary Microglia Front Cell Neurosci, 2020-114(0):590500.
PMID: 33250714
Species: Mouse
Sample Types: Plasma

B Cakir et al. (2020-10-02), IGF1, serum glucose, and retinopathy of prematurity in extremely preterm infants JCI Insight, 2020-15(19).
PMID: 33004691
Species: Mouse
Sample Types: Plasma

D Abboud et al. (2020-09-21), GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11 Nat Commun, 2020-011(1):4752.
PMID: 32958754
Species: Rat
Sample Types: Plasma

W El Bakly et al. (2020-09-21), Optimized platelet rich plasma releasate (O-rPRP) repairs galactosemia-induced ovarian follicular loss in rats by activating mTOR signaling and inhibiting apoptosis Heliyon, 2020-06(9):e05006.
PMID: 33005806
Species: Mouse
Sample Types: Plasma

N Kawamura et al. (2020-09-15), Reduced brain fractalkine-CX3CR1 signaling is involved in the impaired cognition of streptozotocin-treated mice IBRO Rep, 2020-09(0):233-240.
PMID: 32995659
Species: Mouse
Sample Types: Tissue Homogenates

S Yamamoto et al. (2020-08-19), Ursolic acid treatment suppresses cuprizone-induced demyelination and motor dysfunction via upregulation of IGF-1 J. Pharmacol. Sci., 2020-0144(3):119-122.
PMID: 32921392
Species: Rat
Sample Types: Tissue Culture Supernates

KD Beharry et al. (2020-07-03), Combination Antioxidant/NSAID Therapies and Oral/Topical Ocular Delivery Modes for Prevention of Oxygen-Induced Retinopathy in a Rat Model Nutrients, 2020-012(7).
PMID: 32635350
Species: Mouse
Sample Types: Serum

JA Seo et al. (2020-04-24), Apolipoproteinï¿½J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity Nat Commun, 2020-011(1):2024.
PMID: 32332780
Species: Rat
Sample Types: Cell Culture Supernates

KK Poh et al. (2020-04-12), Transplantation of Endothelial Progenitor Cells in Obese Diabetic Rats Following Myocardial Infarction: Role of Thymosin Beta-4 Cells, 2020-09(4).
PMID: 32290541
Species: Rat
Sample Types: Serum

S Guzel et al. (2020-02-02), Bumetanide Suppression of Angiogenesis in a Rat Model of Oxygen-Induced Retinopathy Int J Mol Sci, 2020-021(3).
PMID: 32024231
Species: Rat
Sample Types: Plasma

T Nemoto et al. (2020-01-28), Fetal malnutrition-induced catch up failure is caused by elevated levels of miR-322 in rats Sci Rep, 2020-010(1):1339.
PMID: 31992823
Species: Mouse
Sample Types: Plasma

C Desclée de et al. (2020-01-25), Increased Susceptibility to Obesity and Glucose Intolerance in Adult Female Rats Programmed by High-Protein Diet during Gestation, But Not during Lactation Nutrients, 2020-012(2).
PMID: 31991777
Species: Mouse
Sample Types: Plasma

S Sanchez-Be et al. (2020-01-17), Growth Hormone Promotes Motor Function after Experimental Stroke and Enhances Recovery-Promoting Mechanisms within the Peri-Infarct Area Int J Mol Sci, 2020-021(2).
PMID: 31963456
Species: Mouse
Sample Types: Plasma

R Nakao et al. (2019-12-23), Ketogenic diet induces skeletal muscle atrophy via reducing muscle protein synthesis and possibly activating proteolysis in mice Sci Rep, 2019-19(1):19652.
PMID: 31873138
Species: Mouse
Sample Types: Plasma

T Abe et al. (2019-10-19), Food deprivation during active phase induces skeletal muscle atrophy via IGF-1 reduction in mice Arch. Biochem. Biophys., 2019-10(0):108160.
PMID: 31639326
Species: Rat
Sample Types: Tissue Lysates

CC Hsiao et al. (2019-10-05), Low-Energy Extracorporeal Shock Wave Ameliorates Streptozotocin Induced Diabetes and Promotes Pancreatic Beta Cells Regeneration in a Rat Model Int J Mol Sci, 2019-120(19).
PMID: 31590394
Species: Mouse
Sample Types: Cell Culture Supernates

YZ Zhou et al. (2019-10-04), Mesenchymal stem cell-derived conditioned medium attenuate angiotensin II-induced aortic aneurysm growth by modulating macrophage polarization J. Cell. Mol. Med., 2019-10(0).
PMID: 31583844
Species: Rat
Sample Types: Serum

YF Mahran et al. (2019-08-20), Carvacrol and Thymol Modulate the Cross-Talk between TNF-Î± and IGF-1 Signaling in Radiotherapy-Induced Ovarian Failure Oxid Med Cell Longev, 2019-02019(0):3173745.
PMID: 31531182
Species: Mouse
Sample Types: Plasma

RG Paul et al. (2019-06-24), Regulation of murine skeletal muscle growth by STAT5B is age- and sex-specific Skelet Muscle, 2019-09(1):19.
PMID: 31230596
Species: Rat
Sample Types: Cell Culture Supernates

D Kremer et al. (2019-06-18), pHERV-W envelope protein fuels microglial cell-dependent damage of myelinated axons in multiple sclerosis Proc. Natl. Acad. Sci. U.S.A., 2019-00(0).
PMID: 31213545
Species: Rat
Sample Types: Serum

P Shao et al. (2019-06-15), The interference of DEHP in precocious puberty of females mediated by the hypothalamic IGF-1/PI3K/Akt/mTOR signaling pathway Ecotoxicol. Environ. Saf., 2019-0181(0):362-369.
PMID: 31212184
Species: Mouse
Sample Types: Plasma

G Favaro et al. (2019-06-12), DRP1-mediated mitochondrial shape controls calcium homeostasis and muscle mass Nat Commun, 2019-010(1):2576.
PMID: 31189900
Species: Mouse
Sample Types: Plasma

H Zhou et al. (2019-06-11), Targeting ATGL to rescue BSCL2 lipodystrophy and its associated cardiomyopathy JCI Insight, 2019-05(0).
PMID: 31185001
Species: Rat
Sample Types: Plasma

SH Lee et al. (2019-05-23), Implantable multireservoir device with stimulus-responsive membrane for on-demand and pulsatile delivery of growth hormone Proc. Natl. Acad. Sci. U.S.A., 2019-00(0).
PMID: 31123147
Species: Mouse
Sample Types: Cell Culture Supernates

JM Liefhebber et al. (2019-05-16), In-Depth Characterization of a Mifepristone-Regulated Expression System for AAV5-Mediated Gene Therapy in the Liver Mol Ther Methods Clin Dev, 2019-013(0):512-525.
PMID: 31194088
Species: Mouse
Sample Types: Serum

G Sendžikait et al. (2019-04-23), A DNMT3A PWWP mutation leads to methylation of bivalent chromatin and growth retardation in mice Nat Commun, 2019-010(1):1884.
PMID: 31015495
Species: Mouse
Sample Types: Cell Culture Supernates

IV Kravchenko et al. (2019-03-21), Potassium chloride released from contracting skeletal muscle may stimulate development of its hypertrophy Biochem Biophys Rep, 2019-018(0):100627.
PMID: 30957033
Species: Mouse
Sample Types: Serum

TT Williamson et al. (2019-03-07), Hormone replacement therapy attenuates hearing loss: Mechanisms involving estrogen and the IGF-1 pathway Aging Cell, 2019-00(0):e12939.
PMID: 30845368
Species: Rat
Sample Types: Serum

J Lopez et al. (2019-02-28), Growth Hormone Improves Nerve Regeneration, Muscle Re-innervation, and Functional Outcomes After Chronic Denervation Injury Sci Rep, 2019-09(1):3117.
PMID: 30816300
Species: Mouse
Sample Types: Serum

Y Zhuo et al. (2019-02-13), Fibroblast growth factor 21 coordinates adiponectin to mediate the beneficial effects of low-protein diet on primordial follicle reserve EBioMedicine, 2019-041(0):623-635.
PMID: 30772303
Species: Mouse
Sample Types: Serum

SL Tang et al. (2019-01-18), Pregnancy-Associated Plasma Protein-A Accelerates Atherosclerosis by Regulating Reverse Cholesterol Transport and Inflammation Circ. J., 2019-00(0).
PMID: 30662023
Species: Mouse
Sample Types: Serum

BG Lania et al. (2019-01-04), Topical essential fatty acid oil on wounds: Local and systemic effects PLoS ONE, 2019-014(1):e0210059.
PMID: 30608959
Species: Rat
Sample Types: Plasma

M Machida et al. (2019-01-01), Potentiation of Glucagon-Like Peptide-2 Dynamics by Methotrexate Administration in Rat Small Intestine Biol. Pharm. Bull., 2019-042(10):1733-1740.
PMID: 31582661
Species: Rat
Sample Types: Transfected Whole Cells

S Jung et al. (2018-10-16), Therapeutic effects of a mesenchymal stem cell?based insulin?like growth factor?1/enhanced green fluorescent protein dual gene sorting system in a myocardial infarction rat model Mol Med Rep, 2018-10(0).
PMID: 30365087
Species: Rat
Sample Types: Serum

X Zhang et al. (2018-10-08), Enhanced Pulsatile Growth Hormone Secretion and Altered Metabolic Hormones by in Vivo Hexarelin Treatment in Streptozotocin-Induced Diabetic Rats Int J Mol Sci, 2018-119(10).
PMID: 30297647
Species: Mouse
Sample Types: Plasma

C Bárcena et al. (2018-08-28), Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism Cell Rep, 2018-024(9):2392-2403.
PMID: 30157432
Species: Mouse
Sample Types: Cell Culture Supernates

C Youssif et al. (2018-07-01), Myeloid p38? signaling promotes intestinal IGF-1 production and inflammation-associated tumorigenesis EMBO Mol Med, 2018-00(0).
PMID: 29907597
Species: Mouse
Sample Types: Plasma

K Mao et al. (2018-06-19), Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice Nat Commun, 2018-09(1):2394.
PMID: 29921922
Species: Rat
Sample Types: Serum

AAA Taha et al. (2018-05-08), The effect of the type of dietary protein on the development of ovarian cancer Oncotarget, 2018-09(35):23987-23999.
PMID: 29844867
Species: Mouse
Sample Types: Serum

LK Ong et al. (2018-04-10), Growth Hormone Improves Cognitive Function After Experimental Stroke Stroke, 2018-00(0).
PMID: 29636425
Species: Mouse
Sample Types: Serum

J Lu et al. (2018-04-03), Effects of Intestinal Microbiota on Brain Development in Humanized Gnotobiotic Mice Sci Rep, 2018-08(1):5443.
PMID: 29615691
Species: Rat
Sample Types: Tissue Lysates
Applications: ELISA (Standard)

JD Koerner et al. (2018-03-14), The local cytokine and growth factor response to rhBMP-2 after spinal fusion Spine J, 2018-00(0).
PMID: 29550606
Species: Rat
Sample Types: Tissue Homogenates

C Cai et al. (2018-03-08), Intermittent hypoxia suppression of growth hormone and insulin-like growth factor-I in the neonatal rat liver Growth Horm. IGF Res., 2018-00(0).
PMID: 29544682
Species: Rat
Sample Types: Cell Culture Supernates

L Wang et al. (2018-03-07), Transplant of insulin-like growth factor-1 expressing bone marrow stem cells improves functional regeneration of injured rat uterus by NF-?B pathway J. Cell. Mol. Med., 2018-00(0).
PMID: 29516621
Species: Mouse
Sample Types: Cell Culture Supernates

M Linder et al. (2018-02-14), EGFR controls bone development by negatively regulating mTOR-signaling during osteoblast differentiation Cell Death Differ., 2018-00(0).
PMID: 29445126
Species: Rat
Sample Types: Tissue Homogenates

D Aguado-Lle et al. (2018-02-03), The Protective Effects of IGF-I against ?-Amyloid-related Downregulation of Hippocampal Somatostatinergic System Involve Activation of Akt and Protein Kinase A Neuroscience, 2018-0374(0):104-118.
PMID: 29406271
Species: Mouse
Sample Types: Plasma

Y Takahashi et al. (2018-02-02), Novel phytopeptide osmotin mimics preventive effects of adiponectin on vascular inflammation and atherosclerosis Metab. Clin. Exp., 2018-00(0).
PMID: 29410350
Species: Rat
Sample Types: Serum

BG Lania et al. (2017-12-13), Topical use and systemic action of green and roasted coffee oils and ground oils in a cutaneous incision model in rats (Rattus norvegicus albinus) PLoS ONE, 2017-112(12):e0188779.
PMID: 29236720
Species: Rat
Sample Types: Serum

VST Rodrigues et al. (2017-12-10), Supplementation of suckling rats with cow's milk induces hyperphagia and higher visceral adiposity in females at adulthood, but not in males J. Nutr. Biochem., 2017-155(0):89-103.
PMID: 29413493
Species: Rat
Sample Types: Plasma

M Chennaoui et al. (2017-11-17), Changes of Cerebral and/or Peripheral Adenosine A? Receptor and IGF-I Concentrations under Extended Sleep Duration in Rats Int J Mol Sci, 2017-118(11).
PMID: 29149028
Species: Mouse
Sample Types: Serum

KN Charles et al. (2017-10-10), Uncoupling of Metabolic Health from Longevity through Genetic Alteration of Adipose Tissue Lipid-Binding Proteins Cell Rep, 2017-121(2):393-402.
PMID: 29020626
Species: Rat
Sample Types: Serum

ARR Lima et al. (2017-08-24), Effects of growth hormone on cardiac remodeling and soleus muscle in rats with aortic stenosis-induced heart failure Oncotarget, 2017-08(47):83009-83021.
PMID: 29137319
Species: Mouse
Sample Types: Serum

R Cintron-Co et al. (2017-08-21), Insulin-like growth factor 1 receptor regulates hypothermia during calorie restriction Proc. Natl. Acad. Sci. U.S.A., 2017-00(0).
PMID: 28827363
Species: Mouse
Sample Types: Cell Culture Supernates

XW Tan et al. (2017-08-01), Corticotrophin-releasing hormone and corticosterone impair development of preimplantation embryos by inducing oviductal cell apoptosis via activating the Fas system: an in vitro study Hum. Reprod., 2017-00(0):1-15.
PMID: 28591825
Species: Rat
Sample Types: Serum

M Kugita et al. (2017-05-18), Beneficial effect of combined treatment with octreotide and pasireotide in PCK rats, an orthologous model of human autosomal recessive polycystic kidney disease PLoS ONE, 2017-012(5):e0177934.
PMID: 28542433
Species: Mouse
Sample Types: Serum

M Kondo et al. (2017-04-25), A novel 5HT3 receptor-IGF1 mechanism distinct from SSRI-induced antidepressant effects Mol. Psychiatry, 2017-00(0).
PMID: 28439104
Species: Mouse
Sample Types: Serum

NM Ashpole et al. (2017-04-13), IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan Geroscience, 2017-00(0).
PMID: 28409331
Species: Mouse
Sample Types: Cell Culture Supernates

Z Wang et al. (2017-03-02), Metformin inhibits the proliferation of benign prostatic epithelial cells PLoS ONE, 2017-012(3):e0173335.
PMID: 28253329
Species: Rat
Sample Types: Serum

S Becker et al. (2017-02-14), Protective effect of maternal uteroplacental insufficiency on oxygen-induced retinopathy in offspring: removing bias of premature birth Sci Rep, 2017-07(0):42301.
PMID: 28195189
Species: Mouse
Sample Types: Cell Culture Supernates

L Luo et al. (2017-01-18), Dose-dependency and reversibility of radiation-induced injury in cardiac explant-derived cells of mice Sci Rep, 2017-07(0):40959.
PMID: 28098222
Species: Mouse
Sample Types: Plasma

RJ Tamming et al. (2017-01-12), Mosaic expression of Atrx in the mouse central nervous system causes memory deficits Dis Model Mech, 2017-010(2):119-126.
PMID: 28093507
Species: Mouse
Sample Types: Plasma

Lisa C Burnett (2016-12-12), Deficiency in prohormone convertase PC1 impairs prohormone processing in Prader-Willi syndrome J. Clin. Invest, 2016-10(0).
PMID: 27941249
Species: Mouse
Sample Types: Plasma

(2016-12-09), Positive Prehabilitative Effect of Intense Treadmill Exercise for Ameliorating Cancer Cachexia Symptoms in a Mouse Model J Cancer, 2016-17(15):2378-2387.
PMID: 27994677
Species: Rat
Sample Types: Serum

(2016-12-01), The histone deacetylase inhibitor, sodium butyrate, exhibits neuroprotective effects for ischemic stroke in middle-aged female rats J Neuroinflammation, 2016-113(1):300.
PMID: 27905989
Species: Mouse
Sample Types: Plasma

Li Zhou (2016-11-27), Single chain Fc-dimer-human growth hormone fusion protein for improved drug delivery Biomaterials, 2016-1117(0):24-31.
PMID: 27923197
Species: Mouse
Sample Types: Amniotic Fluid

(2016-11-15), First steps to define murine amniotic fluid stem cell microenvironment Sci Rep, 2016-16(0):37080.
PMID: 27845396
Species: Mouse
Sample Types: Serum

MC Fernandez et al. (2016-10-12), The type I insulin-like growth factor regulates the liver stromal response to metastatic colon carcinoma cells Oncotarget, 2016-18(32):52281-52293.
PMID: 28881729
Species: Mouse
Sample Types: Serum

(2016-08-25), Space radiation exposure persistently increased leptin and IGF1 in serum and activated leptin-IGF1 signaling axis in mouse intestine Sci Rep, 2016-06(0):31853.
PMID: 27558773
Species: Mouse
Sample Types: Serum

Tsutomu Hashidume (2016-06-17), Single ingestion of soy ?-conglycinin induces increased postprandial circulating FGF21 levels exerting beneficial health effects Sci Rep, 2016-06(0):28183.
PMID: 27312476
Species: Mouse
Sample Types: Serum

Thor Tejada (2016-06-06), IGF-1 degradation by mouse mast cell protease 4 promotes cell death and adverse cardiac remodeling days after a myocardial infarction Proc Natl Acad Sci USA, 2016-00(0).
PMID: 27274047
Species: Mouse
Sample Types: Cell Culture Supernates

(2016-05-19), Radiation Exposure Decreases the Quantity and Quality of Cardiac Stem Cells in Mice PLoS ONE, 2016-011(5):e0152179.
PMID: 27195709
Species: Mouse
Sample Types: Plasma

(2016-05-19), Cluster Differentiating 36 (CD36) Deficiency Attenuates Obesity-Associated Oxidative Stress in the Heart PLoS ONE, 2016-011(5):e0155611.
PMID: 27195707
Species: Mouse
Sample Types: Plasma

(2016-05-18), Fibroblast growth factor 21 has no direct role in regulating fertility in female mice Mol Metab, 2016-05(8):690-8.
PMID: 27656406
Species: Mouse
Sample Types: Serum

Baker D et al. (2016-02-03), Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan. Nature, 2016-0530(7589):184-9.
PMID: 26840489
Species: Mouse
Sample Types: Plasma

Conti V et al. (2015-06-22), MeCP2 Affects Skeletal Muscle Growth and Morphology through Non Cell-Autonomous Mechanisms. PLoS ONE, 2015-010(6):e0130183.
PMID: 26098633
Species: Mouse
Sample Types: Cell Culture Supernates

Charolidi N et al. (2015-05-26), Microglial Kv1.3 Channels and P2Y12 Receptors Differentially Regulate Cytokine and Chemokine Release from Brain Slices of Young Adult and Aged Mice. PLoS ONE, 2015-010(5):e0128463.
PMID: 26011191
Species: Mouse
Sample Types: Plasma

Sapra et al. (2014-12-09), The small-molecule BGP-15 protects against heart failure and atrial fibrillation in mice. Nat Commun, 2014-15(0):5705.
PMID: 25489988
Species: Mouse
Sample Types: Serum

Nguyen K et al. (2014-12-09), Glucose intolerance in aging male IGFBP-3 transgenic mice: differential effects of human IGFBP-3 and its mutant IGFBP-3 devoid of IGF binding ability. Endocrinology, 2014-1156(2):462-74.
PMID: 25490144
Species: Mouse
Sample Types: Plasma

Nuytens et al. (2014-10-15), The dwarf phenotype in GH240B mice, haploinsufficient for the autism candidate gene Neurobeachin, is caused by ectopic expression of recombinant human growth hormone. PLoS ONE, 2014-19(10):e109598.
PMID: 25333629
Species: Rat
Sample Types: Serum

Hwang D et al. (2014-09-17), Survival of neural stem cell grafts in the lesioned spinal cord is enhanced by a combination of treadmill locomotor training via insulin-like growth factor-1 signaling. J Neurosci, 2014-034(38):12788-800.
PMID: 25232115
Species: Mouse
Sample Types: Plasma

Zgheib S et al. (2014-08-04), Long-term physiological alterations and recovery in a mouse model of separation associated with time-restricted feeding: a tool to study anorexia nervosa related consequences. PLoS ONE, 2014-09(8):e103775.
PMID: 25090643
Species: Mouse
Sample Types: Serum

Baltes J et al. (2014-06-13), sigma1B adaptin regulates adipogenesis by mediating the sorting of sortilin in adipose tissue. J Cell Sci, 2014-0127(0):3477-87.
PMID: 24928897
Species: Mouse
Sample Types: Plasma

Kuno T et al. (2014-05-22), The peroxisome proliferator-activated receptor (PPAR) alpha agonist fenofibrate suppresses chemically induced lung alveolar proliferative lesions in male obese hyperlipidemic mice. Int J Mol Sci, 2014-015(5):9160-72.
PMID: 24857924
Species: Rat
Sample Types: Serum

Fernandez-Perez L et al. (2014-05-09), Lipid profiling and transcriptomic analysis reveals a functional interplay between estradiol and growth hormone in liver. PLoS ONE, 2014-09(5):e96305.
PMID: 24816529
Species: Mouse
Sample Types: Serum

Harvey A et al. (2014-05-07), Calorie restriction decreases murine and human pancreatic tumor cell growth, nuclear factor-kappaB activation, and inflammation-related gene expression in an insulin-like growth factor-1-dependent manner. PLoS ONE, 2014-09(5):e94151.
PMID: 24804677
Species: Mouse
Sample Types: Tissue Homogenates

Gealekman O et al. (2014-04-28), Control of adipose tissue expandability in response to high fat diet by the insulin-like growth factor-binding protein-4. J Biol Chem, 2014-0289(26):18327-38.
PMID: 24778188
Species: Mouse
Sample Types: Tissue Homogenates

Mellott T et al. (2014-04-14), IGF2 ameliorates amyloidosis, increases cholinergic marker expression and raises BMP9 and neurotrophin levels in the hippocampus of the APPswePS1dE9 Alzheimer's disease model mice. PLoS ONE, 2014-09(4):e94287.
PMID: 24732467
Species: Mouse
Sample Types: Tissue Homogenates

Jiang X et al. (2014-04-09), HGF signaling impacts severity of Pseudomonas aeruginosa keratitis. Invest Ophthalmol Vis Sci, 2014-055(4):2180-90.
PMID: 24618323
Species: Rat
Sample Types: Serum

Ogasawara R et al. (2014-04-01), The order of concurrent endurance and resistance exercise modifies mTOR signaling and protein synthesis in rat skeletal muscle. Am J Physiol Endocrinol Metab, 2014-0306(10):E1155-62.
PMID: 24691029
Species: Mouse
Sample Types: Serum

Oduwole O et al. (2014-03-05), Overlapping dose responses of spermatogenic and extragonadal testosterone actions jeopardize the principle of hormonal male contraception. FASEB J, 2014-028(6):2566-76.
PMID: 24599970
Species: Mouse
Sample Types: Cell Culture Supernates

Piccioni A et al. (2014-02-27), Sonic hedgehog gene therapy increases the ability of the dystrophic skeletal muscle to regenerate after injury. Gene Ther, 2014-021(4):413-21.
PMID: 24572787
Species: Mouse
Sample Types: Tissue Homogenates

Brisson et al. (2014-02-25), Viral expression of insulin-like growth factor I E-peptides increases skeletal muscle mass but at the expense of strength. Am J Physiol Endocrinol Metab, 2014-0306(8):E965-74.
PMID: 24569593
Species: Rat
Sample Types: Serum

Izumi et al. (2014-02-12), Time-dependent expression profiles of microRNAs and mRNAs in rat milk whey. PLoS ONE, 2014-09(2):e88843.
PMID: 24533154
Species: Mouse
Sample Types: Serum

Parlee et al. (2014-01-23), Administration of saccharin to neonatal mice influences body composition of adult males and reduces body weight of females. Endocrinology, 2014-0155(4):1313-26.
PMID: 24456165
Species: Mouse
Sample Types: Serum

Hirose J et al. (2013-12-23), Bone resorption is regulated by cell-autonomous negative feedback loop of Stat5-Dusp axis in the osteoclast. J Exp Med, 2013-1211(1):153-63.
PMID: 24367002
Species: Mouse
Sample Types: Plasma

Keipert S et al. (2013-12-17), Skeletal muscle mitochondrial uncoupling drives endocrine cross-talk through the induction of FGF21 as a myokine. Am J Physiol Endocrinol Metab, 2013-1306(5):E469-82.
PMID: 24347058
Species: Mouse
Sample Types: Tissue Homogenates

Burke R et al. (2013-11-11), BMP9 ameliorates amyloidosis and the cholinergic defect in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A, 2013-1110(48):19567-72.
PMID: 24218590
Species: Mouse
Sample Types: Plasma

Steyn et al. (2013-10-09), Growth hormone secretion is correlated with neuromuscular innervation rather than motor neuron number in early-symptomatic male amyotrophic lateral sclerosis mice. Endocrinology, 2013-1154(12):4695-706.
PMID: 24108071
Species: Mouse
Sample Types: Serum

Ock et al. (2013-08-27), IGF-1 receptor deficiency in thyrocytes impairs thyroid hormone secretion and completely inhibits TSH-stimulated goiter. FASEB J, 2013-027(12):4899-908.
PMID: 23982142
Species: Mouse
Sample Types: Serum

Yamamoto et al. (2013-08-26), SIRT1 regulates adaptive response of the growth hormone--insulin-like growth factor-I axis under fasting conditions in liver. Proc Natl Acad Sci U S A, 2013-0110(37):14948-53.
PMID: 23980167
Species: Mouse
Sample Types: Serum

Lloyd J et al. (2013-07-23), Fish oil slows prostate cancer xenograft growth relative to other dietary fats and is associated with decreased mitochondrial and insulin pathway gene expression. Prostate Cancer Prostatic Dis, 2013-016(4):285-91.
PMID: 23877027
Species: Mouse
Sample Types: Plasma

Al-Qusairi L et al. (2013-05-21), Lack of myotubularin (MTM1) leads to muscle hypotrophy through unbalanced regulation of the autophagy and ubiquitin-proteasome pathways. FASEB J, 2013-027(8):3384-94.
PMID: 23695157
Species: Rat
Sample Types: Serum

Crispel et al. (2013-04-29), Effects of breastfeeding on body composition and maturational tempo in the rat. BMC Med, 2013-011(0):114.
PMID: 23627911
Species: Mouse
Sample Types: Cell Lysates

Osuka S et al. (2013-04-01), IGF1 receptor signaling regulates adaptive radioprotection in glioma stem cells. Stem Cells, 2013-031(4):627-40.
PMID: 23335250
Species: Mouse
Sample Types: Serum

Sen S et al. (2013-01-01), Splicing factor SRSF3 is crucial for hepatocyte differentiation and metabolic function. Nat Commun, 2013-04(0):1336.
PMID: 23299886
Species: Rat
Sample Types: Cell Culture Supernates

Takehara et al. (2012-11-19), The restorative effects of adipose-derived mesenchymal stem cells on damaged ovarian function. Lab Invest, 2012-193(2):181-93.
PMID: 23212100
Species: Mouse
Sample Types: Serum

Al-Dwairi et al. (2012-10-04), Cytosolic Malic Enzyme 1 (ME1) Mediates High Fat Diet-Induced Adiposity, Endocrine Profile, and Gastrointestinal Tract Proliferation-Associated Biomarkers in Male Mice. PLoS ONE, 2012-17(10):e46716.
PMID: 23056418
Species: Rat
Sample Types: Serum

Ma B et al. (2012-03-19), Strontium fructose 1,6-diphosphate prevents bone loss in a rat model of postmenopausal osteoporosis via the OPG/RANKL/RANK pathway. Acta Pharmacol. Sin., 2012-033(4):479-89.
PMID: 22426695
Species: Mouse
Sample Types: Serum

Hua Y et al. (2011-10-05), Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model. Nature, 2011-1478(7367):123-6.
PMID: 21979052
Species: Mouse
Sample Types: Serum

Maurer GD et al. (2011-07-26), Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy. BMC Cancer, 2011-011(0):315.
PMID: 21791085
Species: Mouse
Sample Types: Serum

De Lorenzo M et al. (2011-06-10), Caloric restriction reduces growth of mammary tumors and metastases. Carcinogenesis, 2011-032(9):1381-7.
PMID: 21665891
Species: Mouse
Sample Types: Plasma

Nguyen KH et al. (2011-03-29), Human IGF Binding Protein-3 Overexpression Impairs Glucose Regulation in Mice via an Inhibition of Insulin Secretion. Endocrinology, 2011-0152(6):2184-96.
PMID: 21447640
Species: Mouse
Sample Types: Serum

Sato H et al. (2011-01-25), Physiological roles of group X-secreted phospholipase A2 in reproduction, gastrointestinal phospholipid digestion, and neuronal function. J. Biol. Chem., 2011-0286(13):11632-48.
PMID: 21266581
Species: Mouse
Sample Types: Serum

Yasuda T et al. (2010-08-04), Rim2alpha determines docking and priming States in insulin granule exocytosis. Cell Metab., 2010-012(2):117-29.
PMID: 20674857
Species: Mouse
Sample Types: Plasma

Chambon C et al. (2010-07-26), Myocytic androgen receptor controls the strength but not the mass of limb muscles. Proc. Natl. Acad. Sci. U.S.A., 2010-0107(32):14327-32.
PMID: 20660752
Species: Mouse
Sample Types: Tissue Homogenates

Doverhag C et al. (2010-01-04), Galectin-3 contributes to neonatal hypoxic-ischemic brain injury. Neurobiol. Dis., 2010-038(1):36-46.
PMID: 20053377
Species: Mouse
Sample Types: Tissue Homogenates

Koronyo-Hamaoui M et al. (2009-09-24), Attenuation of AD-like neuropathology by harnessing peripheral immune cells: local elevation of IL-10 and MMP-9. J. Neurochem., 2009-0111(6):1409-24.
PMID: 19780903
Species: Mouse
Sample Types: Serum

Yang H et al. (2008-06-17), Reduction in hypophyseal growth hormone and prolactin expression due to deficiency in ghrelin receptor signaling is associated with Pit-1 suppression: Relevance to the immune system. Brain Behav. Immun., 2008-00(0).
PMID: 18602461
Species: Mouse
Sample Types: Serum

Ashare A et al. (2008-04-24), Insulin-like growth factor-1 improves survival in sepsis via enhanced hepatic bacterial clearance. Am. J. Respir. Crit. Care Med., 2008-0178(2):149-57.
PMID: 18436791
Species: Mouse
Sample Types: Tissue Homogenates

Cheung WW et al. (2008-04-23), Modulation of melanocortin signaling ameliorates uremic cachexia. Kidney Int., 2008-074(2):180-6.
PMID: 18432186
Species: Rat
Sample Types: Serum

Paintlia AS et al. (2008-01-31), Inhibition of rho family functions by lovastatin promotes myelin repair in ameliorating experimental autoimmune encephalomyelitis. Mol. Pharmacol., 2008-073(5):1381-93.
PMID: 18239032
Species: Mouse
Sample Types: Plasma

Kubota Y et al. (2008-01-15), Low-dose GH supplementation reduces the TLR2 and TNF-alpha expressions in visceral fat. Biochem. Biophys. Res. Commun., 2008-0368(1):81-7.
PMID: 18201559
Species: Rat
Sample Types: Plasma

Lanz TA et al. (2007-11-12), Peripheral elevation of IGF-1 fails to alter Abeta clearance in multiple in vivo models. Biochem. Pharmacol., 2007-175(5):1093-103.
PMID: 18076866
Species: Mouse
Sample Types: Serum

Dixit VD et al. (2007-10-01), Ghrelin promotes thymopoiesis during aging. J. Clin. Invest., 2007-1117(10):2778-90.
PMID: 17823656
Species: Mouse
Sample Types: Serum

Wang J et al. (2007-09-20), Microcytosis in ank/ank mice and the role of ANKH in promoting erythroid differentiation. Exp. Cell Res., 2007-0313(20):4120-9.
PMID: 17950726
Species: Rat
Sample Types: Plasma

Yamaleyeva LM et al. (2007-07-13), Ovariectomy is protective against renal injury in the high-salt-fed older mRen2.Lewis rat. Am. J. Physiol. Heart Circ. Physiol., 2007-0293(4):H2064-71.
PMID: 17630347
Species: Mouse
Sample Types: Serum

Engesser-Cesar C et al. (2006-11-28), Wheel running and fluoxetine antidepressant treatment have differential effects in the hippocampus and the spinal cord. Neuroscience, 2006-1144(3):1033-44.
PMID: 17137724

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Customer Reviews for Mouse/Rat IGF-I/IGF-1 Quantikine ELISA Kit (8)

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Mouse/Rat IGF-I/IGF-1 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: Cell culture supernatant

Verified Customer | Posted 06/28/2022
Mouse/Rat IGF-I/IGF-1 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: HUVEC human umbilical vein endothelial cells

Verified Customer | Posted 12/11/2021
Mouse/Rat IGF-I/IGF-1 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: Serum

Verified Customer | Posted 07/06/2021
Mouse/Rat IGF-I/IGF-1 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: rat spinal cord,Spinal cord tissue

Verified Customer | Posted 12/09/2020

Used on rat spinal cord samples and had excellent results.
Mouse/Rat IGF-I/IGF-1 Quantikine ELISA Kit

Name: Jonatan Dereke

Sample Tested: EDTA Plasma

Verified Customer | Posted 11/17/2020

The performance of this analysis was great with samples in the log part of the standard curve.
Mouse/Rat IGF-I/IGF-1 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: EDTA Plasma

Verified Customer | Posted 04/10/2019

We routinely use this ELISA to quantify mouse IGF-1 levels. We have published data from this ELISA. The data shown here confirms previously published data suggesting that IGFBP-1-KO causes increase in IGF-1 levels
Mouse/Rat IGF-I Quantikine ELISA Kit

Name: Leslie Priddy

Sample Tested: Serum

Verified Customer | Posted 04/01/2018
Mouse/Rat IGF-I Quantikine ELISA Kit

Name: Adam Guess

Sample Tested: Cell Culture Supernates

Verified Customer | Posted 11/08/2016

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FAQs for Mouse/Rat IGF-I/IGF-1 Quantikine ELISA Kit

Does this assay recognize total or free IGF-I?

This assay measures total IGF-I. IGF-I bound to IGF Binding Proteins and free IGF-I are detected.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Mouse/Rat IGF-I/IGF-1 Quantikine ELISA Kit Best Seller

Catalog # MG100 | R&D Systems, Inc. a Bio-Techne Brand

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Background: IGF-I/IGF-1

Citations for Mouse/Rat IGF-I/IGF-1 Quantikine ELISA Kit (169)

Customer Reviews for Mouse/Rat IGF-I/IGF-1 Quantikine ELISA Kit (8)

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Mouse/Rat IGF-I/IGF-1 Quantikine ELISA Kit

Mouse/Rat IGF-I/IGF-1 Quantikine ELISA Kit

Mouse/Rat IGF-I/IGF-1 Quantikine ELISA Kit

Mouse/Rat IGF-I/IGF-1 Quantikine ELISA Kit

Mouse/Rat IGF-I/IGF-1 Quantikine ELISA Kit

Mouse/Rat IGF-I/IGF-1 Quantikine ELISA Kit

Mouse/Rat IGF-I Quantikine ELISA Kit

Mouse/Rat IGF-I Quantikine ELISA Kit

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