Human IL-17A/F Heterodimer ELISA Kit (Colorimetric)
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14633
Key Product Details
Sample Type & Volume Required Per Well
Serum, Plasma, Cell culture supernatant (50 ul)
Sensitivity
6.6 pg/ml
Assay Range
15.6-500 pg/ml
Product Specifications
Assay Type
Sandwich ELISA
Kit Type
ELISA Kit (Colorimetric)
Reactivity
Human
Specificity
Recognizes both natural and recombinant human IL-17A/F Heterodimer
Description
Incubation: 3 hours 45 minutes
Precision
Intra-Assay Precision (Precision within an assay) CV% < 7.5
Inter-Assay Precision (Precision between assays) CV% < 7.2
Recovery for Human IL-17A/F Heterodimer ELISA Kit (Colorimetric)
Recovery
77 to 117%
Scientific Data Images for Human IL-17A/F Heterodimer ELISA Kit (Colorimetric)
![ELISA: Human IL-17A/F Heterodimer ELISA Kit (Colorimetric) [NBP3-14633]](https://resources.bio-techne.com/images/products/Human-IL-17A-F-Heterodimer-ELISA-Kit-Colorimetric-ELISA-NBP3-14633-img0001.jpg "ELISA: Human IL-17A/F Heterodimer ELISA Kit (Colorimetric) [NBP3-14633]")
ELISA: Human IL-17A/F Heterodimer ELISA Kit (Colorimetric) [NBP3-14633]
ELISA: Human IL-17A/F Heterodimer ELISA Kit (Colorimetric) [NBP3-14633] - Example of Human IL-17A/F Heterodimer Standard Curve.Kit Contents for Human IL-17A/F Heterodimer ELISA Kit (Colorimetric)
- Biotinylated secondary antibody
- Buffers
- Controls (where applicable)
- Detailed procedure.
- Pre-coated strip plates
- Standards
- Stop reagents
- Streptavidin-HRP
- TMB
Preparation and Storage
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C. Do not freeze.
Background: IL-17A/F Heterodimer
IL-17A/F is a secreted disulfide-linked heterodimer of the cytokines IL-17A and IL-17F. IL-17A/F and the IL-17A and IL-17F homodimers are produced by IL-23 activated Th17 cells. The widely expressed receptors IL-17 RA and IL-17 RC form a heterodimer for the binding of IL-17A and IL-17F, as well as the heterodimeric IL-17A/F. IL-17A/F is a biologically active protein that induces chemokine production and airway neutrophilia with intermediate potency between IL-17A (most potent) and IL-17F (least potent). It is upregulated in immune cells during inflammatory arthritis and contributes to disease severity.
Long Name
Interleukin 17 A/F
Alternate Names
CTLA8, CTLA8cytotoxic T-lymphocyte-associated serine esterase 8, Cytotoxic T-lymphocyte-associated antigen 8, Cytotoxic T-Lymphocyte-Associated Protein 8, IL17, IL-17, IL-17A, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin 17A, interleukin-17A
Gene Symbol
IL17A
Additional IL-17A/F Heterodimer Products
Product Documents for Human IL-17A/F Heterodimer ELISA Kit (Colorimetric)
Product Specific Notices for Human IL-17A/F Heterodimer ELISA Kit (Colorimetric)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.
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