Human VEGFR1/Flt-1 Quantikine ELISA Kit
Catalog # DVR100B | R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Assay Length: | 4.5 hours |
Human VEGFR1/Flt-1 Quantikine ELISA Kit Summary: | The Quantikine Human VEGF R1 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human soluble VEGF R1 in cell culture supernates, serum, plasma, saliva, and follicular fluid. It contains Sf 21-expressed recombinant human VEGF R1/Fc Chimera and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human VEGF R1 showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring soluble VEGF R1. |
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Citations for Human VEGFR1/Flt-1 Quantikine ELISA Kit (81)
Citations are publications that use Bio-Techne products. Selected citations for Human VEGFR1/Flt-1 Quantikine ELISA Kit include:
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Species: Human, Mouse
Sample Types: Cell Culture Supernates, Serum
X Huang et al. (2023-04-14), sFlt-1-enriched exosomes induced endothelial cell dysfunction and a preeclampsia-like phenotype in mice Cytokine, 2023-0166(0):156190.
PMID: 37062152 -
Species: Human
Sample Types: Serum
X Liu et al. (2023-03-20), Interaction between PD-L1 and soluble VEGFR1 in glioblastoma-educated macrophages BMC Cancer, 2023-023(1):259.
PMID: 36941554 -
Species: Human
Sample Types: Plasma
LO Kurlak et al. (2023-02-10), Alterations in Antioxidant Micronutrient Concentrations in Placental Tissue, Maternal Blood and Urine and the Fetal Circulation in Pre-eclampsia International Journal of Molecular Sciences, 2023-024(4).
PMID: 36834991 -
Species: Human
Sample Types: Serum
W Dymara-Kon et al. (2023-01-04), Similar Pro- and Antiangiogenic Profiles Close to Delivery in Different Clinical Presentations of Two Pregnancy Syndromes: Preeclampsia and Fetal Growth Restriction International Journal of Molecular Sciences, 2023-024(2).
PMID: 36674486 -
Species: Human
Sample Types: Serum
J Kaur et al. (2022-06-03), Cholecalciferol supplementation and angiogenic markers in chronic kidney disease PLoS ONE, 2022-017(6):e0268946.
PMID: 35657784 -
Species: Human
Sample Types: Plasma
EO Anto et al. (2022-03-21), Placental lesions and differential expression of pro-and anti-angiogenic growth mediators and oxidative DNA damage marker in placentae of Ghanaian suboptimal and optimal health status pregnant women who later developed preeclampsia PLoS ONE, 2022-017(3):e0265717.
PMID: 35312727 -
Species: Human
Sample Types: Serum
LA Fondjo et al. (2022-03-04), Hematobiochemical variability and predictors of new-onset and persistent postpartum preeclampsia Scientific Reports, 2022-012(1):3583.
PMID: 35246569 -
Species: Human
Sample Types: Protein
AM Nuzzo et al. (2022-01-31), Effect of Placenta-Derived Mesenchymal Stromal Cells Conditioned Media on an LPS-Induced Mouse Model of Preeclampsia International Journal of Molecular Sciences, 2022-023(3).
PMID: 35163594 -
Species: Human
Sample Types: Serum
H Wada et al. (2022-01-20), Impact of Chronic Kidney Disease on the Associations of Cardiovascular Biomarkers With Adverse Outcomes in Patients With Suspected or Known Coronary Artery Disease: The EXCEED-J Study Journal of the American Heart Association, 2022-011(3):e023464.
PMID: 35048713 -
Species: Human
Sample Types: Nuclear Extract
JAF Silva et al. (2021-08-30), Spatial and temporal VEGF receptor intracellular trafficking in microvascular and macrovascular endothelial cells Scientific Reports, 2021-011(1):17400.
PMID: 34462507 -
Species: Human
Sample Types: Cell Culture Supernates
T Jia et al. (2021-08-25), FGF-2 promotes angiogenesis through a SRSF1/SRSF3/SRPK1-dependent axis that controls VEGFR1 splicing in endothelial cells Bmc Biology, 2021-019(1):173.
PMID: 34433435 -
Species: Human
Sample Types: Plasma
S Nabweyambo et al. (2021-05-19), Circulating levels of angiogenic factors and their association with preeclampsia among pregnant women at Mulago National Referral Hospital in Uganda PLoS ONE, 2021-016(5):e0251227.
PMID: 34010327 -
Species: Human
Sample Types: Serum
S Kim et al. (2020-08-31), Circulating miRNAs Associated with Dysregulated Vascular and Trophoblast Function as Target-Based Diagnostic Biomarkers for Preeclampsia Cells, 2020-09(9).
PMID: 32878300 -
Species: Human
Sample Types: Plasma
RC Barbara et al. (2020-06-02), Divergent Impact of Breast Cancer Laterality on Clinicopathological, Angiogenic, and Hemostatic Profiles: A Potential Role of Tumor Localization in Future Outcomes J Clin Med, 2020-09(6).
PMID: 32498398 -
Species: Human
Sample Types: Plasma
DL Wilson et al. (2020-04-27), Sleep-disordered breathing does not impact maternal outcomes in women with hypertensive disorders of pregnancy PLoS ONE, 2020-015(4):e0232287.
PMID: 32339208 -
Species: Human
Sample Types: Placenta
RA Rahman et al. (2020-04-03), Hydroxychloroquine Mitigates the Production of 8-Isoprostane and Improves Vascular Dysfunction: Implications for Treating Preeclampsia Int J Mol Sci, 2020-021(7).
PMID: 32260307 -
Species: Human
Sample Types: Serum
P Nikuei et al. (2020-02-07), Diagnostic accuracy of sFlt1/PlGF ratio as a marker for preeclampsia BMC Pregnancy Childbirth, 2020-020(1):80.
PMID: 32033594 -
Species: Mouse
Sample Types: Tissue Homogenates
MS Dias et al. (2019-09-27), Retina transduction by rAAV2 after intravitreal injection: comparison between mouse and rat Gene Ther., 2019-00(0).
PMID: 31562387 -
Species: Human
Sample Types: Serum
FG Scurt et al. (2019-06-21), Systemic Inflammation Precedes Microalbuminuria in Diabetes Kidney Int Rep, 2019-04(10):1373-1386.
PMID: 31701047 -
Species: Human
Sample Types: Plasma
E Zarychta et al. (2019-02-26), Anti-angiogenic efficacy in invasive breast carcinoma patients depends on clinicopathological determinants Adv Med Sci, 2019-064(2):216-223.
PMID: 30818220 -
Species: Human
Sample Types: Plasma
HW Unger et al. (2019-02-19), Sulphadoxine-pyrimethamine plus azithromycin may improve birth outcomes through impacts on inflammation and placental angiogenesis independent of malarial infection Sci Rep, 2019-09(1):2260.
PMID: 30783215 -
Species: Human
Sample Types: Cell Culture Supernates
M Varas-Godo et al. (2019-01-27), Angiogenic Properties of Menstrual Stem Cells Are Impaired in Women with a History of Preeclampsia Stem Cells Int, 2019-02019(0):1916542.
PMID: 30809262 -
Species: Human
Sample Types: Cell Culture Supernates
C Abou Fayca et al. (2019-01-23), A VEGF-A/SOX2/SRSF2 network controls VEGFR1 pre-mRNA alternative splicing in lung carcinoma cells Sci Rep, 2019-09(1):336.
PMID: 30674935 -
Species: Human
Sample Types: Plasma
P Villie et al. (2018-12-18), ELABELA concentration is not decreased in maternal plasma before the onset of preeclampsia Am. J. Obstet. Gynecol., 2018-1220(3):284-285.
PMID: 30576665 -
Species: Human
Sample Types: Cell Lysates
SHS Lee et al. (2018-11-01), Intravitreal Injection of AAV Expressing Soluble VEGF Receptor-1 Variant Induces Anti-VEGF Activity and Suppresses Choroidal Neovascularization Invest. Ophthalmol. Vis. Sci., 2018-159(13):5398-5407.
PMID: 30452593 -
Species: Mouse
Sample Types: Tissue Homogenates
JA Sandgren et al. (2018-10-04), Arginine vasopressin infusion is sufficient to model clinical features of preeclampsia in mice JCI Insight, 2018-13(19).
PMID: 30282823 -
Species: Mouse, Rabbit
Sample Types: Tissue Homogenates, Vitreous Humor
JA Sullivan et al. (2018-05-22), Rationally designed AAV2 and AAVrh8R capsids provide improved transduction in the retina and brain Gene Ther., 2018-00(0).
PMID: 29785047 -
Species: Human
Sample Types: Serum
GS Stødle et al. (2018-04-23), Placental inflammation in pre-eclampsia by Nod-like receptor protein (NLRP)3 inflammasome activation in trophoblasts Clin. Exp. Immunol., 2018-00(0).
PMID: 29683202 -
Species: Human
Sample Types: Cell Culture Supernates
H Tanaka et al. (2018-03-24), Arginase controls soluble vascular endothelial growth factor receptor 1 (sFlt1) to maintain pregnancy homeostasis Biochem. Biophys. Res. Commun., 2018-00(0).
PMID: 29548823 -
Species: Human
Sample Types: Plasma
H Li et al. (2018-01-23), LIFR increases the release of sEng via the up-regulation of MMP14 expression in PE Reproduction, 2018-00(0).
PMID: 29363569 -
Species: Human
Sample Types: Cell Culture Supernates
M Eslani et al. (2017-10-01), Corneal Mesenchymal Stromal Cells Are Directly Antiangiogenic via PEDF and sFLT-1 Invest. Ophthalmol. Vis. Sci., 2017-158(12):5507-5517.
PMID: 29075761 -
Species: Human
Sample Types: Tissue Culture Supernates
M O'Brien et al. (2017-07-19), Endothelial Dysfunction in Severe Preeclampsia is Mediated by Soluble Factors, Rather than Extracellular Vesicles Sci Rep, 2017-07(1):5887.
PMID: 28725005 -
Species: Human
Sample Types: Plasma
A Dutta et al. (2017-05-29), Household air pollution and angiogenic factors in pregnant Nigerian women: A randomized controlled ethanol cookstove intervention Sci. Total Environ., 2017-0599(0):2175-2181.
PMID: 28575932 -
Species: Human
Sample Types: Cell Culture Supernates
AF Pantho et al. (2017-05-11), Synthetic Receptors Induce Anti Angiogenic and Stress Signaling on Human First Trimester Cytotrophoblast Cells Int J Environ Res Public Health, 2017-014(5).
PMID: 28492503 -
Species: Human
Sample Types: Tissue Homogenates
Shingo Takano (2016-12-19), The anti-angiogenic role of soluble-form VEGF receptor in malignant gliomas Int. J. Oncol, 2016-10(0).
PMID: 28000842 -
Species: Human
Sample Types: Cell Culture Supernates
Sushil Panta (2016-12-18), Low grade inflammation inhibits VEGF induced HUVECs migration in p53 dependent manner Biochem. Biophys. Res. Commun, 2016-10(0).
PMID: 27998768 -
Species: Human
Sample Types: Serum
VS Jammalamad et al. (2016-12-01), Spectrum of Factors Triggering Endothelial Dysfunction in PIH J Clin Diagn Res, 2016-110(12):BC14-BC17.
PMID: 28208844 -
Species: Human
Sample Types: Plasma
(2016-09-26), Albuminuria Is Associated with Endothelial Dysfunction and Elevated Plasma Endothelin-1 in Sickle Cell Anemia PLoS ONE, 2016-011(9):e0162652.
PMID: 27669006 -
Species: Human
Sample Types: Tissue Homogenates
Ingrid C Weel (2016-06-17), Association between Placental Lesions, Cytokines and Angiogenic Factors in Pregnant Women with Preeclampsia PLoS ONE, 2016-011(6):e0157584.
PMID: 27315098 -
Species: Human
Sample Types: Cell Culture Supernates
Bessho H et al. (2015-01-01), Inhibition of placental growth factor in renal cell carcinoma. Anticancer Res, 2015-035(1):531-41.
PMID: 25550599 -
Species: Human
Sample Types: Serum
Sallinen H et al. (2014-09-23), Serum angiopoietin-2 and soluble VEGFR-2 levels predict malignancy of ovarian neoplasm and poor prognosis in epithelial ovarian cancer. BMC Cancer, 2014-014(0):696.
PMID: 25245329 -
Species: Human
Sample Types: Serum
Owen et al. (2014-05-08), FLT1 genetic variation predisposes to neovascular AMD in ethnically diverse populations and alters systemic FLT1 expression. Invest Ophthalmol Vis Sci, 2014-055(6):3543-54.
PMID: 24812550 -
Species: Human
Sample Types: Serum
White W et al. (2014-03-24), Persistent urinary podocyte loss following preeclampsia may reflect subclinical renal injury. PLoS ONE, 2014-09(3):e92693.
PMID: 24664365 -
Species: Human
Sample Types: Plasma
Necchi A et al. (2013-11-14), Analysis of plasma cytokines and angiogenic factors in patients with pretreated urothelial cancer receiving Pazopanib: the role of circulating interleukin-8 to enhance the prognostic accuracy. Br J Cancer, 2013-1110(1):26-33.
PMID: 24231947 -
Species: Human
Sample Types: Serum
Liu et al. (2013-11-06), Integrating multiple 'omics' analyses identifies serological protein biomarkers for preeclampsia. BMC Med, 2013-111(0):236.
PMID: 24195779 -
Species: Human
Sample Types: Serum
El-Tarhouny S et al. (2013-08-13), Placental growth factor and soluble Fms-like tyrosine kinase 1 in diabetic pregnancy: A possible relation to distal villous immaturity. Histol Histopathol, 2013-029(2):259-72.
PMID: 23939615 -
Species: Human
Sample Types: Cell Culture Supernates
Justiniano S et al. (2013-07-31), Fcgamma receptor-induced soluble vascular endothelial growth factor receptor-1 (VEGFR-1) production inhibits angiogenesis and enhances efficacy of anti-tumor antibodies. J Biol Chem, 2013-0288(37):26800-9.
PMID: 23902770 -
Species: Human
Sample Types: Cell Culture Supernates
Huang Q et al. (2013-07-27), Advanced oxidation protein products enhances soluble Fms-like tyrosine kinase 1 expression in trophoblasts: a possible link between oxidative stress and preeclampsia. Placenta, 2013-034(10):949-52.
PMID: 23899470 -
Species: Human
Sample Types: Serum
Suzuki T et al. (2013-04-09), A randomized controlled trial of multicomponent exercise in older adults with mild cognitive impairment. PLoS ONE, 2013-08(4):e61483.
PMID: 23585901 -
Species: Human
Sample Types: Serum
Braicu E et al. (2013-02-14), Role of serum concentration of VEGFR1 and TIMP2 on clinical outcome in primary cervical cancer: results of a companion protocol of the randomized, NOGGO-AGO phase III adjuvant trial of simultaneous cisplatin-based radiochemotherapy vs. carboplatin and paclitaxel containing sequential radiotherapy. Cytokine, 2013-061(3):755-8.
PMID: 23415672 -
Species: Human
Sample Types: Plasma
Patten IS et al. (2012-05-09), Cardiac angiogenic imbalance leads to peripartum cardiomyopathy. Nature, 2012-0485(7398):333-8.
PMID: 22596155 -
Species: Human
Sample Types: Serum
Landt S et al. (2011-08-01), In vitro vascular tube formation testing as a tool for treatment individualisation in patients with cervical cancer. Anticancer Res., 2011-031(8):2609-15.
PMID: 21778312 -
Species: Human
Sample Types: Serum
Landt S et al. (2011-08-01), Prognostic significance of angiogenic factors in uterine cervical cancer. Anticancer Res., 2011-031(8):2589-95.
PMID: 21778309 -
Species: Human
Sample Types: Serum
Rahbari NN et al. (2011-07-05), Expression and prognostic value of circulating angiogenic cytokines in pancreatic cancer. BMC Cancer, 2011-011(0):286.
PMID: 21729304 -
Species: Human
Sample Types: Plasma
Dubois SG et al. (2011-06-20), Phase I and pharmacokinetic study of sunitinib in pediatric patients with refractory solid tumors: a children's oncology group study. Clin. Cancer Res., 2011-017(15):5113-22.
PMID: 21690570 -
Species: Human
Sample Types: Serum
Jeyabalan A et al. (2010-10-12), Effect of smoking on circulating angiogenic factors in high risk pregnancies. PLoS ONE, 2010-15(10):e13270.
PMID: 20967275 -
Species: Human
Sample Types: Serum
Powers RW et al. (2010-10-11), Soluble fms-Like tyrosine kinase 1 (sFlt1), endoglin and placental growth factor (PlGF) in preeclampsia among high risk pregnancies. PLoS ONE, 2010-15(10):e13263.
PMID: 20948996 -
Species: Human
Sample Types: Plasma
Jeevaratnam K et al. (2010-09-28), Periodic assessment of plasma sFlt-1 and PlGF concentrations and its association with placental morphometry in gestational hypertension (GH) - a prospective follow-up study. BMC Pregnancy Childbirth, 2010-010(0):58.
PMID: 20920154 -
Species: Human
Sample Types: Urine
Kosugi T et al. (2009-12-16), Soluble Flt-1 gene therapy ameliorates albuminuria but accelerates tubulointerstitial injury in diabetic mice. Am. J. Physiol. Renal Physiol., 2009-1298(3):F609-16.
PMID: 20015944 -
Species: Human
Sample Types: Serum
Levine RJ et al. (2009-11-17), Pre-eclampsia, soluble fms-like tyrosine kinase 1, and the risk of reduced thyroid function: nested case-control and population based study. BMJ, 2009-1339(0):b4336.
PMID: 19920004 -
Species: Human
Sample Types: Serum
Verlohren S et al. (2009-10-21), An automated method for the determination of the sFlt-1/PIGF ratio in the assessment of preeclampsia. Am. J. Obstet. Gynecol., 2009-1202(2):161.e1-161.e1.
PMID: 19850276 -
Species: Human
Sample Types: Serum
Bourlev V et al. (2009-03-25), Signs of reduced angiogenic activity after surgical removal of deeply infiltrating endometriosis. Fertil. Steril., 2009-094(1):52-7.
PMID: 19324337 -
Species: Human
Sample Types: Plasma
Sandhofer A et al. (2009-02-03), Are plasma VEGF and its soluble receptor sFlt-1 atherogenic risk factors? Cross-sectional data from the SAPHIR study. Atherosclerosis, 2009-0206(1):265-9.
PMID: 19237157 -
Species: Human
Sample Types: Plasma
Sallinen H et al. (2008-12-02), Antiangiogenic gene therapy with soluble VEGFR-1, -2, and -3 reduces the growth of solid human ovarian carcinoma in mice. Mol. Ther., 2008-117(2):278-84.
PMID: 19050699 -
Species: Human
Sample Types: Cell Culture Supernates, Plasma
Muehlenbachs A et al. (2008-09-08), Natural selection of FLT1 alleles and their association with malaria resistance in utero. Proc. Natl. Acad. Sci. U.S.A., 2008-0105(38):14488-91.
PMID: 18779584 -
Species: Human
Sample Types: Plasma
Findley CM et al. (2008-07-29), Plasma levels of soluble Tie2 and vascular endothelial growth factor distinguish critical limb ischemia from intermittent claudication in patients with peripheral arterial disease. J. Am. Coll. Cardiol., 2008-052(5):387-93.
PMID: 18652948 -
Species: Human
Sample Types: Plasma
Jeyabalan A et al. (2008-06-19), Cigarette smoke exposure and angiogenic factors in pregnancy and preeclampsia. Am. J. Hypertens., 2008-021(8):943-7.
PMID: 18566591 -
Species: Human
Sample Types: Serum
Gutman G et al. (2008-03-17), Regulation of vascular endothelial growth factor-A and its soluble receptor sFlt-1 by luteinizing hormone in vivo: implication for ovarian follicle angiogenesis. Fertil. Steril., 2008-089(4):922-6.
PMID: 18343373 -
Species: Human
Sample Types: Serum
Clavel G et al. (2007-06-08), Angiogenesis markers (VEGF, soluble receptor of VEGF and angiopoietin-1) in very early arthritis and their association with inflammation and joint destruction. Clin. Immunol., 2007-0124(2):158-64.
PMID: 17560831 -
Species: Human
Sample Types: Plasma
Caine GJ et al. (2007-01-19), Significant decrease in angiopoietin-1 and angiopoietin-2 after radical prostatectomy in prostate cancer patients. Cancer Lett., 2007-0251(2):296-301.
PMID: 17240049 -
Species: Human
Sample Types: Serum
Wallner W et al. (2007-01-01), Angiogenic growth factors in maternal and fetal serum in pregnancies complicated by intrauterine growth restriction. Clin. Sci., 2007-0112(1):51-7.
PMID: 16928195 -
Species: Human
Sample Types: Serum
Levine RJ et al. (2006-09-07), Soluble endoglin and other circulating antiangiogenic factors in preeclampsia. N. Engl. J. Med., 2006-0355(10):992-1005.
PMID: 16957146 -
Species: Human
Sample Types: Plasma
Caine GJ et al. (2006-08-07), Changes in plasma vascular endothelial growth factor, angiopoietins, and their receptors following surgery for breast cancer. Cancer Lett., 2006-0248(1):131-6.
PMID: 16891056 -
Species: Human
Sample Types: Serum
Masuyama H et al. (2006-02-01), Circulating angiogenic factors in preeclampsia, gestational proteinuria, and preeclampsia superimposed on chronic glomerulonephritis. Am. J. Obstet. Gynecol., 2006-0194(2):551-6.
PMID: 16458660 -
Species: Human
Sample Types: Serum
Mross K et al. (2005-06-01), Phase I clinical and pharmacokinetic study of PTK/ZK, a multiple VEGF receptor inhibitor, in patients with liver metastases from solid tumours. Eur. J. Cancer, 2005-041(9):1291-9.
PMID: 15939265 -
Species: Human
Sample Types: Urine
Buhimschi CS et al. (2005-03-01), Urinary angiogenic factors cluster hypertensive disorders and identify women with severe preeclampsia. Am. J. Obstet. Gynecol., 2005-0192(3):734-41.
PMID: 15746665 -
Species: Human
Sample Types: Cell Culture Supernates
Li H et al. (2005-02-01), Hypoxia-induced increase in soluble Flt-1 production correlates with enhanced oxidative stress in trophoblast cells from the human placenta. Placenta, 2005-026(2):210-7.
PMID: 15708122 -
Species: Human
Sample Types: Urine
Levine RJ et al. (2005-01-05), Urinary placental growth factor and risk of preeclampsia. JAMA, 2005-0293(1):77-85.
PMID: 15632339 -
Species: Human
Sample Types: Cell Culture Supernates
Eubank TD et al. (2004-12-01), GM-CSF induces expression of soluble VEGF receptor-1 from human monocytes and inhibits angiogenesis in mice. Immunity, 2004-121(6):831-42.
PMID: 15589171 -
Species: Human
Sample Types: Serum
Levine RJ et al. (2004-02-05), Circulating angiogenic factors and the risk of preeclampsia. N. Engl. J. Med., 2004-0350(7):672-83.
PMID: 14764923 -
Species: Human
Sample Types: Serum
Maynard SE et al. (2003-03-01), Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. J. Clin. Invest., 2003-0111(5):649-58.
PMID: 12618519
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